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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
369 Results for "
CI
" in MedChemExpress (MCE) Product Catalog:
Products (369)
369 Results for "CI" in MCE Product Catalog:
Cat. No.: HY-105226
CAS No.: 130332-27-3
Synonyms: PD134308
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CI-988 (PD134308) is a potent, selective and orally active CCK2R (cholecystokinin 2 receptor) antagonist with an IC50 of 1.7 nM for mouse cortex CCK2. CI-988 shows >1600-fold selectivity for CCK2 over CCK1 receptor. CI-988 has anxiolytic and anti-tumor effects .
Cat. No.: HY-105235
CAS No.: 124378-77-4
Synonyms: CI-977
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Enadoline (CI-977) is a highly selective, brain-penetrating, and nonpeptide kappa-opioid receptor (KOR) agonist (Ki=1.25 nM). Antinociceptive effects .
Synonyms: CI-1004 mesylate
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Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50 = 0.19 μM) but is much less potent with PGHS-1 (IC50= 20 μM).
Cat. No.: HY-105403
CAS No.: 253450-09-8
Synonyms: CI-1041; Co 200461; PD 0196860
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Besonprodil (CI-1041) is a potent NMDA antagonist .
Cat. No.: HY-W001273
CAS No.: 72869-16-0
Synonyms: CI-879 sulfate
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Pramiracetam (CI-879) sulfate Pramiracetam is a PREP (prolyl endopeptidase) inhibitor. Pramiracetam sulfate improves cognitive impairment caused by traumatic brain injury. Pramiracetam sulfate can be used in the study of neurodegenerative diseases .
Cat. No.: HY-115231
CAS No.: 1009832-82-9
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ci-IP3/PM is a caged and cell permeable derivative of IP3. ci-IP3/PM can induce Ca 2+ release from internal stores .
Cat. No.: HY-U00364
CAS No.: 104961-19-5
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CI-949 is an allergic mediator release inhibitor, which inhibits histamine, leukotriene C4/D4 (LTC4/LTD4), and thromboxane B2 (TXB2) release with IC50s of 11.4 μM, 0.5 μM and 0.1 μM, respectively.
Cat. No.: HY-118047
CAS No.: 115787-68-3
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CI 972 anhydrous is a potent, orally active, and competitive inhibitor of purine nucleoside phosphorylase (PNP) (Ki=0.83 μM) under development as a T cell-selective immunosuppressive agent .
Cat. No.: HY-106995
CAS No.: 200195-01-3
Synonyms: CI 1030
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PD 172760 (CI 1030) is a selective D4 receptor antagonist. PD 172760 along with the action of other neurotransmitter receptors may be important in study psychosis .
Cat. No.: HY-D0508
CAS No.: 15792-43-5
Cat. No.: HY-10373A
CAS No.: 1658520-97-8
Synonyms: CI-898 trihydrochloride
Trimetrexate (CI-898) trihydrochloride is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate trihydrochloride can also inhibit the growth of various cancer cells. Trimetrexate trihydrochloride can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer .
Cat. No.: HY-D0482
CAS No.: 12222-00-3
Cat. No.: HY-100161
CAS No.: 89239-35-0
Synonyms: (±)-CI-943
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CI-943 is a potential antipsychotic agent.
Cat. No.: HY-122133
CAS No.: 47739-68-4
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CI 750 is an orally active antidiarrheal agent. CI 750 exhibits antidiarrheal activity in monkeys and rats. CI 750 can be used for the research of diarrhea .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
