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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9407 Results for "
Modified Oligonucleotide
" in MedChemExpress (MCE) Product Catalog:
Products (9407)
9407 Results for "Modified Oligonucleotide" in MCE Product Catalog:
Synonyms: RG6091 sodium; RO7248824 sodium
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Rugonersen sodium is a locked-nucleic acid (LNA)- modified antisense oligonucleotides (ASOs), and results in reduction of ubiquitin-protein ligase E3A (UBE3A) silencing. Angelman syndrome (AS) sodium is a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A, Rugonersen has been used for AS reasearch .
Cat. No.: HY-D2328A
CAS No.: 407628-16-4
Synonyms: Alexa Fluor 680 succinimidyl ester diTEA
Phosphoramidite is a modified phosphoramidite monomer used for the oligonucleotide synthesis.
Cat. No.: HY-D1089
CAS No.: 113394-23-3
Cat. No.: HY-139785
CAS No.: 2378664-12-9
Synonyms: AST-008
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Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.
Cat. No.: HY-W881465
CAS No.: 2172373-55-4
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5'(E)-VP-2'-OMe-U Phosphoramidite is a phosphoramidite nucleotide precursor compound, mainly used to synthesize stable and functionalized modified oligonucleotides for the research and synthesis of nucleic acid drugs.
Cat. No.: HY-RI00057
hsa-miR-107 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
Cat. No.: HY-W115309
CAS No.: 144089-96-3
Synonyms: 5'-DMT-2'-F-ibu-dG
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DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets .
Cat. No.: HY-W141393
CAS No.: 128219-77-2
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2'-OMe-dmf-G-CE-phosphoramidite is a phosphoramidite monomer used in the preparation or synthesis of oligonucleotides. As a chemically protected guanosine phosphoramidite derivative, 2'-OMe-dmf-G-CE-phosphoramidite is employed in the solid-phase synthesis of 2'-O-methyl-modified oligonucleotides.
Cat. No.: HY-W881466
CAS No.: 2419895-65-9
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5'(E)-VP-2'-OMe-Bz-A Phosphoramidite is a phosphoramidate nucleotide precursor compound, which is mainly used to synthesize stable and functionalized modified oligonucleotides and is used in the development and synthesis of nucleic acid drugs .
Cat. No.: HY-W1119950
CAS No.: 1644649-86-4
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3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite is an adenine nucleotide monomer precursor used in solid-phase synthesis of oligonucleotides, particularly modified oligonucleotides, such as those with DNA chain end modifications. 3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite, with trityl (Tr), cyanoethyl (CE), and dimethylformamidine (DMF) protecting groups, is a ddNTP adenosine nucleoside useful in applications such as solid-phase oligonucleotide synthesis, probe design, and chain-termination sequencing .
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Mal-amido-PEG1-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules
Cat. No.: HY-139785A
Synonyms: AST-008 sodium
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Cavrotolimod sodium is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.
Cat. No.: HY-W744780
CAS No.: 160801-26-3
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Docosahexaenoic Acid N-Succinimide is the succinimide analog of Docosahexaenoic Acid. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Cat. No.: HY-W800819
CAS No.: 69888-87-5
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Arachidic Acid N-Hydroxysuccinimide Ester is a lipid comprised of a saturated fatty acid with a 20-carbon chain with a terminal NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Cat. No.: HY-148828
CAS No.: 1235945-37-5
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LSP-GR3 is a novel chemically-modified RNA oligonucleotides, called splice modulating oligomers (SMOs), which potently and specifically modulate GluR alternative splicing to GluR3-flip expression throughout the CNS.
Cat. No.: HY-148828A
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LSP-GR3 sodium is a novel chemically-modified RNA oligonucleotides, called splice modulating oligomers (SMOs), which potently and specifically modulate GluR alternative splicing to GluR3-flip expression throughout the CNS.
Cat. No.: HY-W784562
CAS No.: 159639-78-8
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5'-O-DMTr-2'-O-TBDMS-5-Me-U-3'-CE Phosphoramidite is a nucleoside phosphoramidite monomer modified with protecting groups and can be used in RNA oligonucleotide synthesis.
Cat. No.: HY-W749072
CAS No.: 2227463-25-2
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BP Fluor 568 NHS ester is an amine-reactive, orange fluorescent dye routinely used to label proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules (Ex/Em: 578 nm/602 nm) .
Cat. No.: HY-W1119943
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2'-OMe-8-Me-DMF-G Phosphoramidite is a phosphoramidite compound containing modified guanine (G) and a dimethoxytrityl (DMT) group. 2'-OMe-8-Me-DMF-G Phosphoramidite can be used in RNA oligonucleotide synthesis.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
