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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
144 Results for "
cellular responses
" in MedChemExpress (MCE) Product Catalog:
Products (144)
144 Results for "cellular responses" in MCE Product Catalog:
Cat. No.: HY-161767
CAS No.: 3069975-17-0
Research Areas:
JWJ-01-306 is a CRBN-recruiting ZBTB11 Molecular Glues degrader. JWJ-01-306 degrades ZBTB11 and reprograms cellular metabolism, thereby reducing the level of Oxidative Phosphorylation and the activity of the tricarboxylic acid cycle. JWJ-01-306 enhances the response of organoids to K-Ras inhibition. JWJ-01-306 inhibits the proliferation of pancreatic ductal adenocarcinoma cells and melanoma cells. JWJ-01-306 can be used in studies related to pancreatic ductal adenocarcinoma and melanoma .
Target:
Research Areas:
Fumarase catalyses the conversion of l-malic acid to fumaric acid. Fumarase participates in the tricarboxylic acid cycle in mitochondria. Fumarase participates in the cellular response to DNA double strand breaks .
Cat. No.: HY-E70625
Target:
Research Areas:
Casein Kinase 2 (CK2) is a serine/threonine protein kinase that is highly conserved among eukaryotes and has roles in many different cellular processes, such as cell survival, cell cycle regulation, cell polarity, stress responses, transcription and translation .
Cat. No.: HY-B0389S8
CAS No.: 106032-61-5
Synonyms: Glucose-d1-4; D-(+)-Glucose-d1-4; Dextrose-d1-4
Cat. No.: HY-B0389S2
CAS No.: 89798-27-6
Synonyms: Glucose-d12-1; D-(+)-Glucose-d12-1; Dextrose-d12-1
Target:
Research Areas:
Phospholipase C (PLCs) is a class of phospholipases. Phospholipase C participates in cellular signaling and regulation by virtue of its ability to hydrolyze membrane phospholipids into di-acyl-glycerol (DAG) and inositol triphosphate (IP3), which further causes the activation of other signaling pathways involved in various processes, including immune response .
Cat. No.: HY-113313R
CAS No.: 52-39-1
Cat. No.: HY-113469B
Purity: 99.07%
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Cyclic GMP (cGMP) TBAOH, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP TBAOH occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .
Cat. No.: HY-B0389S14
CAS No.: 201741-04-0
Synonyms: Glucose-13C2; D-(+)-Glucose-13C2; Dextrose-13C2
Cat. No.: HY-B0389S12
CAS No.: 120388-24-1
Synonyms: Glucose-5-13C; D-(+)-Glucose-5-13C; Dextrose-5-13C
Cat. No.: HY-148980
CAS No.: 30918-54-8
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Research Areas:
Polyinosinic acid is a single stranded homonucleic acid, which is a Toll-like Receptor 3 (TLR3) ligand. Polyinosinic acid enhances cellular immune response through TLR3 and TRIF. Polyinosinic acid has potential applications in immune regulation .
Cat. No.: HY-106765A
Purity: 99.94%
Synonyms: RGH-0205 TFA; TP3 TFA
Target:
Research Areas:
Cat. No.: HY-B0389S4
CAS No.: 51517-59-0
Synonyms: Glucose-d1-2; D-(+)-Glucose-d1-2; Dextrose-d1-2
Cat. No.: HY-B0389S11
CAS No.: 84270-10-0
Synonyms: Glucose-4-13C; D-(+)-Glucose-4-13C; Dextrose-4-13C
Cat. No.: HY-B0389S13
CAS No.: 105931-74-6
Synonyms: Glucose-2-13C; D-(+)-Glucose-2-13C; Dextrose-2-13C
Cat. No.: HY-B0389S9
CAS No.: 478529-47-4
Synonyms: Glucose-13C3-2; D-(+)-Glucose-13C3-2; Dextrose-13C3-2
Cat. No.: HY-123924
CAS No.: 2244984-64-1
Target:
Research Areas:
CSLP37 is a selective RIPK2 inhibitor with an IC50 of 16.3 nM. CSLP37 shows no inhibitory activity against RIPK1 and RIPK3. CSLP37 displays potent suppression of cellular NOD1 and NOD2 responses .
Cat. No.: HY-B0389S17
CAS No.: 106032-62-6
Synonyms: Glucose-6-13C; D-(+)-Glucose-6-13C; Dextrose-6-13C
Cat. No.: HY-147215
CAS No.: 927822-45-5
Target:
Research Areas:
UC-1V150 is a specific TLR7 (Toll-like receptor) agonist that stimulates cellular immune responses and has anti-tumor activity. UC-1V150 can be used to synthesize ISAC (Immune-Stimulating Antibody Conjugates) molecule .
Cat. No.: HY-174620
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Human IL22 mRNA encodes the human interleukin 22 (IL22) protein, a member of the IL10 family of cytokines that mediate cellular inflammatory responses. IL22 functions in antimicrobial defense at mucosal surfaces and in tissue repair. It also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
