127 Results for "

cotransporter

" in MedChemExpress (MCE) Product Catalog:
Products (127)

127 Results for "cotransporter" in MCE Product Catalog:

Cat. No.: HY-122613
CAS No.: 655237-16-4
Target:  

SGLT

Research Areas:  

Metabolic Disease

YM543 free base is a potent and orally active sodium-glucose cotransporter (SGLT) 2 inhibitor. YM543 free base reduces blood glucose levels. YM543 free base can be used in research of diabetes .
loading...
    loading...
Cat. No.: HY-12611
CAS No.: 408504-26-7
Purity:  99.64%
Synonyms: GW-869682X
Target:  

SGLT

Research Areas:  

Metabolic Disease

Sergliflozin etabonate (GW-869682X) is a potent and orally active sodium glucose cotransporter (SGLT2) inhibitor. Sergliflozin etabonate shows antidiabetic and antihyperglycemic effects. Sergliflozin etabonate significantly reduces non-fasting blood glucose levels in diabetic mice. Sergliflozin etabonate has the potential for the research of diabetes .
loading...
    loading...
Cat. No.: HY-W727334
CAS No.: 41745-47-5
Research Areas:  

Others

H-Glu-Pro-OH is a Xaa-Pro dipeptide with affinity for the intestinal H +/peptide cotransporter (PEPT1), with a Ki value of 0.26 mM .
loading...
    loading...
Cat. No.: HY-18172A
CAS No.: 1228439-71-1
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

(+)-KCC2 blocker 1 is a selective K +-Cl - cotransporter KCC2 blocker with an IC50 of 0.4 μM. (+)-KCC2 blocker 1 is a benzyl prolinate and a enantiomer of KCC2 blocker 1 .
loading...
    loading...
Cat. No.: HY-114308
CAS No.: 1240305-17-2
Target:  

SGLT

Research Areas:  

Metabolic Disease

SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. SGL5213 has potential to treat type 2 diabetes treatment .
loading...
    loading...
Cat. No.: HY-100322
CAS No.: 643727-55-3
Target:  

Chloride Channel

Research Areas:  

Cardiovascular Disease

H100 is a Cl - transport inhibitor, with partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger, but no effect against KCl cotransporter, in human erythrocytes.
loading...
    loading...
Cat. No.: HY-168989
CAS No.: 2035989-50-3
Target:  

SGLT

Research Areas:  

Metabolic Disease

Olorigliflozin is a sodium glucose co-transporter inhibitor with anti-hyperglycemic effects .
loading...
    loading...
Cat. No.: HY-19298
CAS No.: 151165-96-7
S-8921 is an ileal Na +/bile acid cotransporter (IBAT) inhibitor.
loading...
    loading...
Cat. No.: HY-15409S1
Synonyms: BI 10773-13C6
Empagliflozin- 13C6 (BI 10773- 13C6) is 13C labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2 .
loading...
    loading...
Cat. No.: HY-15409S2
Synonyms: BI 10773-d6
Empagliflozin-d6 (BI 10773-d6) is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2 .
loading...
    loading...
Cat. No.: HY-109092A
CAS No.: 2730989-98-5
Synonyms: rel-LIK066
Target:  

SGLT

rel-Licogliflozin is a relative configuration of Licogliflozin (HY-109092). Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor .
loading...
    loading...
Cat. No.: HY-112807
CAS No.: 2247314-23-2
Target:  

SGLT

Research Areas:  

Metabolic Disease

SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively .
loading...
    loading...
Cat. No.: HY-B1477R
CAS No.: 636-54-4
Clopamide (Standard) is the analytical standard of Clopamide. This product is intended for research and analytical applications. Clopamide is an orally active thiazide-like diuretic agent that inhibits the sodium-coupled chloride cotransporter SLC12A3. Clopamide has the potential for hypertension and cardiac failure research .
loading...
    loading...
Cat. No.: HY-178167
Target:  

SGLT

Research Areas:  

Metabolic Disease

SGLT2-IN-3 is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. SGLT2-IN-3 can inhibit glucose uptake. SGLT2-IN-3 can be used for the research of metabolic disease, such as diabetes .
loading...
    loading...
Cat. No.: HY-17468A
CAS No.: 28434-74-4
Synonyms: Ro 10-6338 sodium; PF 1593 sodium
Target:  

NKCC

Bumetanide sodium, a highly potent loop diuretic, is a Na +-K +-Cl + cotransporter (NKCC) blocker. Bumetanide sodium is a selective NKCC1 inhibitor, and also inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively .
loading...
    loading...
Cat. No.: HY-15461S
CAS No.: 1298086-22-2
Synonyms: PF-04971729-d5
Ertugliflozin-d5 is the deuterium labeled Ertugliflozin . Ertugliflozin (PF-04971729) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2 . Has the potential for the treatment of type 2 diabetes mellitus .
loading...
    loading...
Cat. No.: HY-15461S1
Synonyms: PF-04971729-d9
Ertugliflozin-d9 is deuterated labeled Ertugliflozin (HY-15461). Ertugliflozin (PF-04971729) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2 . Has the potential for the treatment of type 2 diabetes mellitus .
loading...
    loading...
Cat. No.: HY-10450S5
Dapagliflozin- 13C6-1 is 13C labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
loading...
    loading...
Cat. No.: HY-10450S2
CAS No.: 1224234-25-6
Synonyms: BMS-512148-d4
Dapagliflozin-d4 (BMS-512148-d4) is deuterium labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
loading...
    loading...
Cat. No.: HY-10450S3
Synonyms: BMS-512148-13C6
Dapagliflozin- 13C6 (BMS-512148- 13C6) is 13C labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
loading...
    loading...