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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
326 Results for "
dimer
" in MedChemExpress (MCE) Product Catalog:
Products (326)
326 Results for "dimer" in MCE Product Catalog:
Cat. No.: HY-138291
CAS No.: 74681-77-9
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Ethoxyquin dimer is a dimer of Ethoxyquin (HY-B1425). Ethoxyquin dimer is an antioxidant. Ethoxyquin dimer can more readily accumulate in liver and adipose tissue compared with Ethoxyquin. Ethoxyquin above 10 mg/kg shows hepatotoxicity in mice .
Cat. No.: HY-175004
CAS No.: 1821339-88-1
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PBD dimer-4 (Compound 7) is a C1-subsitituted PBD dimer. PBD dimer-4 has high DNA-binding affinity, DNA cross-linking ability and potent cytotoxicity against MDA-MB-231 cells (IC50: 236 nM). PBD dimer-4 can be used as a payload of ADC Loncastuximab tesirine (HY-P99349) to treat several different cancer types .
Cat. No.: HY-N10638
CAS No.: 916888-49-8
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N-Acetyldopamine dimer-2 (compound 2) is a N-acetyldopamine dimer that can be isolated from the yellow powder form Periostracum Cicadae with antioxidant and anti-inflammatory activities. N-Acetyldopamine dimer-2 inhibits oxidized low-density lipoprotein (LDL) oxidation, ROS generation, NO production, and NF-κB activity .
Cat. No.: HY-W020940
CAS No.: 12012-95-2
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Allylpalladium(II) chloride dimer is a palladium catalytic precursor that serves as a catalyst for the Heck reaction. Allylpalladium(II) chloride dimer is also a transition metal allyl complex .
Cat. No.: HY-136113
CAS No.: 2031255-23-7
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Ibrutinib dimer is an impurity of Ibrutinib (HY-10997). Ibrutinib is a tyrosine kinase inhibitor. Ibrutinib can be used for research on B-cell malignancies .
Cat. No.: HY-W033831
CAS No.: 142214-04-8
Synonyms: Rh2(TPA)4
Rhodium(II) triphenylacetate dimer (Rh2(TPA)4) is an important catalyst with high C–H activation reaction activity. Rhodium(II) triphenylacetate dimer is widely used in organic synthesis to achieve the construction of complex molecules. Rhodium(II) triphenylacetate dimer can also be used to catalyze the synthesis of certain biologically active molecules and improve the preparation efficiency of compounds. Rhodium(II) triphenylacetate dimer exhibits excellent selectivity and reaction rate in catalytic reactions.
Cat. No.: HY-W587729
CAS No.: 24388-68-9
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Ethylene terephthalate cyclic dimer is a intermediate of polyethylene terephthalate (PET). PET is a common plastic used in fibers and packaging materials.
Synonyms: (E)-2-Undecenoic acid; (E)-Undec-2-enoic acid
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trans-2-Undecenoic acid ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid and is characterized by acid dimers. The corresponding dimers are connected via intermolecular hydrogen bonds of the carboxylic groups C=O···H-O .
Cat. No.: HY-Y1094
CAS No.: 12092-47-6
Synonyms: Chloro(1,5-cyclooctadiene)rhodium(I) dimer
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[Rh(cod)Cl]2 (Chloro (1,5-cyclooctadiene) rhodium (I) dimer) is an organometallic rhodium (I) dimer precursor and platelet aggregation inhibitor. [Rh(cod)Cl]2 inhibits PAF-induced aggregation in washed rabbit platelets. [Rh(cod)Cl]2 inhibits aggregation induced by PAF, Thrombin, ADP and Collagen in human platelet-rich plasma. [Rh(cod)Cl]2 acts as a catalyst precursor for the hydrogenation of aromatic hydrocarbons, phenols, olefins and BINOL derivatives. [Rh(cod)Cl]2 is used in the research of cardiovascular diseases such as thromboinflammation-related disorders, tumor metastasis and atherosclerosis .
Cat. No.: HY-E70578
CAS No.: 52227-85-7
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T4 Endonuclease V is a dual-activity DNA glycosylase that combines the activities of DNA N-glycosylase and AP lyase. T4 Endonuclease V can repair ultraviolet (UV)-induced cyclobutane pyrimidine dimers in DNA .
Cat. No.: HY-174293
CAS No.: 2564638-97-5
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Osimertinib dimer is a dimer of Osimertinib (HY-15772). Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer .
Cat. No.: HY-N10637
CAS No.: 315188-82-0
N-Acetyldopamine dimer-1 is a 2-(3',4'-dihydroxyphenyl)-1,4-benzodioxane derivative. N-Acetyldopamine dimer-1 is optically active, can be isolated from crude agent "Zentai," a cast-off shell of the cicada of Cryptotympana sp. (Cicadidae) .
Cat. No.: HY-P5213
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Cat. No.: HY-126678
CAS No.: 3026416-27-0
Synonyms: Dimethyl-PBD dimer
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Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly potent DNA alkylator, and is used as an antibody-drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylator which inhibits DNA replication .
Cat. No.: HY-P3223A
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Cat. No.: HY-W025817
CAS No.: 99-11-6
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Citrazinic acid is a weakly fluorescent compound whose optical properties are dependent on aggregation states and chemical environment. Citrazinic acid strongly tends to form dimers at high concentrations .
Cat. No.: HY-N10766
CAS No.: 151487-08-0
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Cat. No.: HY-164492
CAS No.: 1455031-68-1
LSN3074753, an analog of LY3009120 (HY-12558), is a pan-RAF and Raf dimer inhibitor. LSN3074753 demonstrates activity against tumor cells with MAPK pathway activation driven by BRAF monomer or RAF dimers including BRAF- or KRAS-mutant colorectal cancer. LSN3074753 combined with Cetuximab (HY-P9905) shows additive and synergistic effects for colorectal cancer PDX models, particularly those with KRAS or BRAF mutation .
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Cat. No.: HY-D1660
CAS No.: 57576-49-5
Synonyms: NSC 219743
Acridine homodimer (NSC 219743), acridine dimer, is a fluorescence dye. Acridine homodimer emits a blue-green fluorescence when bound to DNA. Acridine homodimer has extremely high affinity for AT-rich regions of nucleic acids, can be used for chromosome banding .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
