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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
326 Results for "
dimer
" in MedChemExpress (MCE) Product Catalog:
Products (326)
326 Results for "dimer" in MCE Product Catalog:
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1 Cited Publications
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NVS-STG2 is a molecular glue that targets STINGdimer transmembrane domains, effectively acting as a molecular glue. NVS-STGI enhances the activity of cGAMP by inducing the formation of more abundant and larger oligomers. NVS-STG2 produces antitumor activity in animal models .
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1 Cited Publications
Cat. No.: HY-P1441A
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1 Cited Publications
Cat. No.: HY-W040129
CAS No.: 7059-24-7
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1 Cited Publications
Cat. No.: HY-30014
CAS No.: 348640-06-2
Synonyms: PBD dimer
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SGD-1882 is a cytotoxic, DNA minor-groove crosslinking agent pyrrolobenzodiazepine (PBD) dimer, acting as the payload for ADCs.
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N,N'-diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine is a potent, orally active modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits .
Synonyms: DRG16
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SG2057 (DRG16) is a PBD dimer containing a pentyldioxy linkage which binds sequence selectively in the minor groove of DNA forming DNA interstrand and intrastrand cross-linked adducts. SG2057 is a highly active antitumor agent .
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PBD dimer-2 (compound 2c) is a C8-linked pyrrolobenzodiazepine dimer. PBD dimer-2 can span an extra base pair and cross-link the 5′-Pu-GA(T/A)TC-Py sequence. PBD dimer-2 can be used as a payload for antibody–agent conjugates (ADCs), and it can be used for the research of cancer .
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Infection Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
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Synonyms: NCD
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Naphthyridine carbamate dimer (NCD) is a molecular glue. Naphthyridine carbamate dimer induces designed structural changes in target functional DNA, thereby regulating its function. As a molecular glue, naphthyridine carbamate dimer stabilizes non-spontaneously formed GG homologous mismatched double-stranded DNA. Naphthyridine carbamate dimer reduces the formation of toxic RNA foci and regulates CGG repeat instability associated with fragile X syndrome and spinocerebellar ataxia type 31. Naphthyridine carbamate dimer can be used in research related to fragile X syndrome and spinocerebellar ataxia type 31 .
Cat. No.: HY-D0916
CAS No.: 143413-85-8
Synonyms: YOYO 1; YOYO1
Cat. No.: HY-Y1109
CAS No.: 52462-29-0
Synonyms: Tetrachlorobis(mu-4-cymene)diruthenium(II)
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Dichloro(p-cymene)ruthenium(II) dimer (Tetrachlorobis(mu-4-cymene)diruthenium(II)) is a ruthenium-based organometallic catalyst precursor, which is widely applied in the field of organic synthesis .
Cat. No.: HY-P3432
CAS No.: 2035480-78-3
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Cat. No.: HY-W033466
CAS No.: 37366-09-9
Synonyms: Benzeneruthenium(II) chloride dimer
Cat. No.: HY-P3215
CAS No.: 19645-28-4
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Cat. No.: HY-P3222
CAS No.: 20054-93-7
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Cat. No.: HY-W097819
CAS No.: 2092-49-1
Synonyms: Dehydrodivanillin
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Cat. No.: HY-79986
CAS No.: 90614-07-6
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Diiodo(p-cymene)ruthenium(II) dimer is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-W020887
CAS No.: 12246-51-4
Synonyms: Chlorobis(cyclooctene)iridium(I)dimer
[IrCl(COE)2]2 (Chlorobis(cyclooctene)iridium(I)dimer) is a transition metal catalyst with remarkable catalytic activity. It is widely used in catalyzing a variety of organic reactions, especially in the synthesis of unsaturated compounds. In addition, [IrCl(COE)2]2 has shown potential anti-tumor properties in biochemical research.
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Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers . Bis-propargyl-PEG4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
