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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
87 Results for "
Curcumin
" in MedChemExpress (MCE) Product Catalog:
Products (87)
87 Results for "Curcumin" in MCE Product Catalog:
Cat. No.: HY-N0006S
CAS No.: 2470243-19-5
Synonyms: Curcumin II-d7; DesmethoxyCurcumin-d7; MonodemethoxyCurcumin-d7
Cat. No.: HY-163451
CAS No.: 3126845-21-1
Apoptosis inducer 17 is a Curcumin-Piperlongumine hybrid molecule that increases cell cycle arrest and apoptosis through activating JNK signaling pathway in lung cancer cells .
Cat. No.: HY-W009731R
CAS No.: 120-46-7
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Cat. No.: HY-100977S
CAS No.: 3006902-95-7
Synonyms: DiMC-d6; CHC 004-d6; Di-O-methylCurcumin-d6
Cat. No.: HY-W030796AR
CAS No.: 150436-68-3
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Bisdemethoxycucurmin (Standard) is the analytical standard of Bisdemethoxycucurmin. This product is intended for research and analytical applications. Bisdemethoxycucurmin (Curcumin III), a curcuminoid, has antioxidant and antiinflammatory activities .
Cat. No.: HY-W721191
Cat. No.: HY-116117
CAS No.: 1236545-54-2
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Cat. No.: HY-163458
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Anti-inflammatory agent 77 (C12) is a β-cycloacinamide derived mono-carbonyl curcumin analog and an inhibitor of interleukin-6 (IL-6). Anti-inflammatory agent 77 can be used in the study of wound healing .
Category:
Human Gut Microbiota Metabolites Microorganisms Monophenols Pseudostellaria heterophylla (Miq.) Pax Ketones, Aldehydes, Acids Phenols Plants Endogenous metabolite Caryophyllaceae
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Cat. No.: HY-W745860
CAS No.: 2469279-20-5
Cat. No.: HY-139804
CAS No.: 1297262-16-8
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CTK7A is a curcumin derivative with anticancer activity by inhibiting the HAT activity of p300 and reducing the autoacetylation of p300, thereby affecting its interaction with HIF-1α. The inhibition of CTK7A leads to decreased HIF-1α accumulation and activity, which can be used for cancer research .
Cat. No.: HY-W440901
DSPE-PEG5000-SPDP is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents. The core can encapsulate hydrophilic nutrients, such as protein/peptide and mRNA/DNA/siRNA etc. while the lipid bilayer can solubilize hydrophobic drugs, such as doxorubicin, curcumin etc. The SPDP moiety can react with thiol molecule to form a disulfide bond.
Cat. No.: HY-123715
CAS No.: 1983924-20-4
Anticancer agent 255 is a monocarbonylated curcumin-1,2,3-oxazole conjugate with significant anticancer activity. The IC50 values of Anticancer agent 255 in prostate cancer cells PC-3 and DU-145 are 8.8μM and 9.5μM respectively. The IC50 values of Anticancer agent 255 against breast cancer cells MCF-7, MDA-MB-231 and 4T1 are 6μM, 10μM and 6.4μM, showing good anti-cancer activity Effect. Anticancer agent 255 can induce mitochondria-mediated apoptosis in cancer cells and prevent cell cycle progression. Anticancer agent 255 down-regulated the cell proliferation marker PCNA and inhibited the activation of cell survival proteins. Anticancer agent 255 up-regulated the pro-apoptotic protein Bax and down-regulated the anti-apoptotic protein Bcl-2 .
Cat. No.: HY-178924
Antibacterial agent 298 exhibits significant antibacterial activity against Pseudomonas putida (ATCC 25922) with an IC50 4.48 µg/mL. Antibacterial agent 298 shows strong antibiofilm activity. Antibacterial agent 298 also inhibits approximately 50% of biofilm formation in L. lactis and P. putida. Antibacterial agent 298 can be used for the study of Bacterial infections caused by multidrug-resistant bacteria (MDR) .
Cat. No.: HY-134635R
CAS No.: 1080-12-2
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Dehydrozingerone (Standard) is the analytical standard of Dehydrozingerone. This product is intended for research and analytical applications. Dehydrozingerone (Compound 10), a structural half analogue of Curcumin (HY-N0005), is a phenolic compound with antibacterial, anticancer, antioxidant, anti-Alzheimer’s and antifungal activity, which is isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone shows moderate inhibitory activities on the secretion of HBsAg in HepG 2 cells with an IC50 value of 0.50 mM .
Cat. No.: HY-N0894A
CAS No.: 408324-14-1
Synonyms: (3R,5R)-HexahydrobisdemethoxyCurcumin
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Cat. No.: HY-186288
CAS No.: 3061366-78-4
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DYRK2 ligand 2 is a curcumin analog and an inhibitor targeting DYRK2, which serves as a ligand for target protein for PROTAC against DYRK2. DYRK2 ligand 2 is applicable to studies related to PROTAC synthesis, such as for PROTAC DYRK2 degrader-2 (HY-186287) .
Cat. No.: HY-N17436
CAS No.: 138870-92-5
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Cat. No.: HY-N18668
CAS No.: 84775-52-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
