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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
87 Results for "
Curcumin
" in MedChemExpress (MCE) Product Catalog:
Products (87)
87 Results for "Curcumin" in MCE Product Catalog:
Cat. No.: HY-139211
CAS No.: 1170354-22-9
Synonyms: 3,4-Difluorobenzylidene Curcumin
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Difluorinated Curcumin (3,4-Difluorobenzylidene curcumin) is a fluorinated curcumin analog with high bioavailability and anticancer activity. Difluorinated Curcumin inhibits the self-renewal ability of tumor stem/stem-like cells, clonogenicity, invasiveness and angiogenesis of tumor cells. Difluorinated Curcumin also increases cell sensitivity to chemotherapy .
Cat. No.: HY-137315S
CAS No.: 2673270-28-3
Cat. No.: HY-15668
CAS No.: 1370037-59-4
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ST09 is an efficient and low toxicity Curcumin (HY-N0005) derivative. ST09 significantly inhibits cell migration and downregulates the expression of MMP1, MMP2, and Vimentin. ST09 has strong cytotoxicity to breast cancer cells, such as MDA-MB-231, MCF7 and T47D cells. ST09 induces cell apoptosis by upregulating Bax and cleaved caspase-3/9. ST09 can be used in the research of cancer such as breast cancer .
Cat. No.: HY-N0005S1
Synonyms: Diferuloylmethane-d3; Natural Yellow 3-d3; Turmeric yellow-d3
Cat. No.: HY-N0007S
CAS No.: 2470233-08-8
Synonyms: Curcumin III-d8; DidemethoxyCurcumin-d8
Cat. No.: HY-186012
CAS No.: 3032193-08-8
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TPP@CUR is the product formed by the esterification reaction between Curcumin (HY-N0005) and (5-hydroxy-5-oxopentyl)triphenylphosphonium bromide (TPP). TPP@CUR can be used to synthesize Ser@TPP@CUR (HY-151342), which can then be used in studies of acute kidney injury .
Cat. No.: HY-143421
CAS No.: 2171091-50-0
Synonyms: CMG
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Curcumin monoglucuronide is known as a glucuronic acid conjugate, which is one of the in vivo metabolites of curcumin. Curcumin monoglucuronide is used for research on the metabolism of curcumin and examination of its development as a pharmaceutical. Curcumin monoglucuronide has the potential for the research of cancer disease (extracted from patent WO2022004873A1) .
Cat. No.: HY-179398
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Keap1-Nrf2-IN-29 (Compound 1a), a Curcumin (HY-N0005) analog, is a Keap1 protein inhibitor. Keap1-Nrf2-IN-29 exhibits significant inhibitory activity against A549, PC-3 and MCF-7 cells. Keap1-Nrf2-IN-29 can be used for the study of prostate cancer .
Cat. No.: HY-151342
CAS No.: 3032193-12-4
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Ser@TPP@CUR is a Curcumin (HY-N0005) derivative. Ser@TPP@CUR effectively ameliorates injured renal tubular epithelial cells and improves renal functions of acute kidney injury (AKI) mice. Ser@TPP@CUR can be used for the research of AKI .
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Cyclovalone (Beveno) is a synthetic curcumin derivate, which inihibits cyclooxygenase and exhibits anti-inflammatory, antitumor and antioxidant activities . Cyclovalone inhibits cell proliferation in normal and malignant prostatic cells. Cyclovalone ist orally active .
Cat. No.: HY-120914
CAS No.: 170950-29-5
Synonyms: GO-Y015
TrxR1-IN-B19 (GO-Y015) (Compound B19) is a Curcumin (HY-N0005) derivative and colvalent TrxR1 inhibitor. TrxR1-IN-B19 inhibits TrxR1 enzyme activity to elevate oxidative stress, and then induce ROS-mediated ER Stress and mitochondrial dysfunction, subsequently resulting in cell cycle arrest and apoptosis .
Cat. No.: HY-177840
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Liposomal Curcumin is a specialized delivery system that encapsulates Curcumin (HY-N0005) within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of Curcumin. Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
The product size below only indicate the effective content of Curcumin.
The product size below only indicate the effective content of Curcumin.
Cat. No.: HY-150673S
Cat. No.: HY-N12669
CAS No.: 387818-26-0
Cat. No.: HY-150674S
Synonyms: Curcumin-d6-β-di-glucoside tetraacetate; DiglucosylCurcumin-d6 octaacetate
Cat. No.: HY-W749302
CAS No.: 2734308-81-5
Cat. No.: HY-143676S
CAS No.: 1335198-02-1
Cat. No.: HY-122757
CAS No.: 131068-23-0
Synonyms: Curcumin pyrazole
Hydrazinocurcumin (Curcumin pyrazole) is a potent endothelial cell proliferation inhibitor (IC50=520 nM). Hydrazinocurcumin disrupts angiogenic signaling pathways and inhibits endothelial cell migration and tube formation, exerting anti-angiogenic activity. Hydrazinocurcumin is promising for research of tumor angiogenesis inhibition, metastatic cancer, and vascular-dependent diseases such as retinopathies .
Cat. No.: HY-N2317
CAS No.: 60831-46-1
Synonyms: BisdemethylCurcumin; LI-01008
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Cat. No.: HY-W717038
CAS No.: 2734137-34-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
