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Cat. No.: HY-N12669

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Curcumin monoglucoside

Curcumin monoglucoside is a flavonoid derivative possessing antioxidant, anti-apoptotic, neuroprotective effects, and antibacterial activity. Curcumin monoglucoside can be used in research on Parkinson's disease.

For research use only. We do not sell to patients.

CAS No.: 387818-26-0
Formula: C₂₇H₃₀O₁₁
Molecular Weight:530.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Curcumin monoglucoside Chemical Structure

CAS No.: 387818-26-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All JNK Isoforms :

All Caspase Isoforms :

In Vitro

Curcumin monoglucoside (5µM; 24 h) exhibits anti-apoptotic effects in N27 cells by inhibiting the activation of caspase 3 through the prevention of JNK and c-jun phosphorylation^[1].
Curcumin monoglucoside (0.25-5µM; 24 h) significantly protects N27 cells from ROT (500 nM; 24 h)-induced neuronal death, demonstrating neuroprotective effects^[1].
Curcumin monoglucoside exhibits antibacterial activity, with MIC (Minimum Inhibitory Concentration) values of 5, 5, and 10 μg/mL respectively against penicillin-sensitive, penicillin-intermediate, and penicillin-resistant strains of Streptococcus pneumoniae^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Curcumin monoglucoside (500µM) exerts antioxidant effects in the ROT Drosophila model by increasing GSH levels and decreasing ROS^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 387818-26-0
Molecular Weight 530.52
Formula C₂₇H₃₀O₁₁
SMILES

COC(C=C(C=C1)/C=C/C(CC(/C=C/C2=CC(OC)=C(C=C2)O)=O)=O)=C1O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO
Structure Classification
- Saccharides
- Monosaccharides
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pandareesh MD, et al. Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson's Disease. Neurochem Res. 2016 Nov;41(11):3113-3128. [Content Brief]

[2]. Li L M, et al. Antimicrobial and molecular interaction studies on derivatives of curcumin against Streptococcus pneumoniae which caused pneumonia[J]. Electronic Journal of Biotechnology, 2016, 19: 8-14.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References

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Curcumin monoglucoside

All JNK Isoforms

All Caspase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Curcumin monoglucoside Related Classifications

HY-N12669 Related Classifications