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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
109 Results for "
DNA alkylating
" in MedChemExpress (MCE) Product Catalog:
Products (109)
109 Results for "DNA alkylating" in MCE Product Catalog:
Cat. No.: HY-17364R
CAS No.: 85622-93-1
Synonyms: NSC 362856 (Standard); CCRG 81045 (Standard); TMZ (Standard)
Research Areas:
Temozolomide (Standard) is the analytical standard of Temozolomide. This product is intended for research and analytical applications. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects .
Cat. No.: HY-136291
Target:
Research Areas:
Sulfo-SPDB-DGN462 is a agent-linker conjugate for ADC. Sulfo-SPDB-DGN462 consists a toxin DGN462 (HY-101150) conjugated to the cleavable Sulfo-SPDB linker. DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML).
Cat. No.: HY-13567S
CAS No.: 2070015-32-4
Synonyms: SDX-105-d4 free base
Cat. No.: HY-E70605
Target:
Research Areas:
Human alkyl adenine DNA glycosylase is a monomeric DNA glycosylase that corrects a broad range of alkylated and deaminated nucleobases to maintain genomic integrity .
Cat. No.: HY-16117A
CAS No.: 203258-38-2
Synonyms: PNU-166196
Target:
Research Areas:
Brostallicin (PNU-166196) is a DNA alkylating agent with potent cytotoxicity and low myelotoxicity .
Cat. No.: HY-19577
CAS No.: 85754-59-2
Synonyms: PTT119
Target:
Ambamustine (PTT119) is a bifunctional alkylating agent and induces DNA damage by alkylating mechanisms. Ambamustine interferes with late steps in murine mammary tumor virus (MuMTV) processing and maturation and reduces production of the B-type retrovirus MuMTV. Ambamustine possesses cytolytic and antiviral activities .
Cat. No.: HY-N15366
CAS No.: 115722-78-6
Category:
Target:
Cat. No.: HY-W701673
CAS No.: 1276372-62-3
Cat. No.: HY-W588285
CAS No.: 2958-98-7
Synonyms: 3-MG
Target:
Research Areas:
3-Methylguanine is a DNA damage product caused by alkylation. 3-Methylguanine is cytotoxic and causes cell death by inhibiting DNA replication. 3-Methylguanine can be used to study the mechanism of DNA damage caused by alkylating agents and its repair pathways .
Cat. No.: HY-161051
CAS No.: 3034231-46-1
Target:
Research Areas:
Anticancer agent 177 (Compound 11b) is a NAMPT inhibitor and DNA alkylating agent. Anticancer agent 177 has antitumor activity in vitro and in vivo .
Cat. No.: HY-101002
CAS No.: 81965-43-7
Synonyms: SarCNU; Sarmustine
Target:
Research Areas:
Sarcosinamide chloroethylnitrosourea is an orally active alkylating agent. Sarcosinamide chloroethylnitrosourea can induce apoptosis by promoting DNA alkylation. Sarcosinamide chloroethylnitrosourea can be used in cancer-related research .
Cat. No.: HY-B0077S1
CAS No.: 1185068-23-8
Synonyms: SDX-105-d8
Cat. No.: HY-13567S1
CAS No.: 1134803-33-0
Synonyms: SDX-105-d8 free base
Research Areas:
Bendamustine (hydrochloride) (Standard) is the analytical standard of Bendamustine (hydrochloride). This product is intended for research and analytical applications. Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties .
Cat. No.: HY-119696R
CAS No.: 3413-72-7
Target:
Research Areas:
MTIC (Standard) is the analytical standard of MTIC. This product is intended for research and analytical applications. MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity
[1][2][3][4].
Cat. No.: HY-16513R
CAS No.: 23261-20-3
Synonyms: Dianhydrodulcitol (Standard); Dianhydrogalactitol (Standard)
Research Areas:
VAL-083 (Standard) is the analytical standard of VAL-083. This product is intended for research and analytical applications. VAL-083 is an alkylating agent that creates N7 methylation on DNA, with antitumor activity.
Cat. No.: HY-13567R
CAS No.: 16506-27-7
Synonyms: SDX-105 free base (Standard)
Research Areas:
Bendamustine (Standard) is the analytical standard of Bendamustine. This product is intended for research and analytical applications. Bendamustine (SDX-105 free base), a purine analogue, is a DNA cross-linking agent. Bendamustine activates DNA-damage stress response and apoptosis. Bendamustine has potent alkylating, anticancer and antimetabolite properties .
Category:
Cat. No.: HY-W738282
Synonyms: SDX-105-d7
Research Areas:
Pipobroman (Standard) is the analytical standard of Pipobroman. This product is intended for research and analytical applications. Pipobroman is a bromide derivative of piperazine and acts as an alkylating agent. Pipobroman plays its role by inhibiting DNA and RNA polymerase or by reducing pyrimidine nucleotide incorporation into DNA. Pipobroman can be used for the cancer research, including polycythemia vera, myeloproliferative neoplasm, and AML et.al .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
