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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
74 Results for "
ALK-2
" in MedChemExpress (MCE) Product Catalog:
Products (74)
74 Results for "ALK-2" in MCE Product Catalog:
Cat. No.: HY-183720
CAS No.: 2600795-21-7
Research Areas:
M4K2163 is a ALK2 inhibitor that serves as a target protein ligand for the synthesis of PROTACs, such as M4K3250 (HY-183718). M4K2163 induces cytotoxic effects in glioblastoma cells. M4K2163 can be used in the research of diffuse intrinsic pontine glioma and glioblastoma .
Cat. No.: HY-19928R
CAS No.: 1352608-82-2
Synonyms: EW-7197 (Standard); TEW-7197 (Standard)
Target:
Research Areas:
Vactosertib (Standard) is the analytical standard of Vactosertib (HY-19928). This product is intended for research and analytical applications. Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like Kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect [2].
Cat. No.: HY-13418AR
CAS No.: 866405-64-3
Synonyms: BML-275 (Standard)
Research Areas:
Dorsomorphin (Standard) is the analytical standard of Dorsomorphin (HY-13418A). This product is intended for research and analytical applications. Dorsomorphin (BML-275) is a selective and ATP-competitive AMPK inhibitor (Ki=109 nM in the absence of AMP). Dorsomorphin (BML-275) selectively inhibits BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599) [2].
Cat. No.: HY-12071R
CAS No.: 1062368-24-4
Synonyms: DM-3189 (Standard)
Research Areas:
LDN193189 (Standard) is the analytical standard of LDN193189 (HY-12071). This product is intended for research and analytical applications. LDN193189 (DM-3189) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva [2] .
Cat. No.: HY-12278G
CAS No.: 1431985-92-0
Cat. No.: HY-P72812
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
HEK293
Cat. No.: HY-P72769
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
HEK293
Cat. No.: HY-P7482
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
HEK293
Cat. No.: HY-P705731
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705732
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705733
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705734
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705735
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705993
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
