81 Results for "

PSI

" in MedChemExpress (MCE) Product Catalog:
Products (81)

81 Results for "PSI" in MCE Product Catalog:

Cat. No.: HY-15236S1
Synonyms: RO 2433--d1,13C,15N2; GS-331007--d1,13C,15N2
PSI-6206-d1, 13C, 15N2 is 15N and 13C labeled PSI-6206 (HY-15236). PSI-6206 (RO 2433) is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibits HCV replicon with EC90 of >100 μM.
loading...
    loading...
Cat. No.: HY-P0192
CAS No.: 213130-17-7
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 is a nociceptin receptor (ORL1) agonist. [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 strongly depresses the nociceptive flexor reflex in rats. [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 can be used for analgesia research .
loading...
    loading...
Cat. No.: HY-P5510
CAS No.: 188530-20-3
Synonyms: HCV NS3 protease substrate
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. (This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM.
loading...
    loading...
Cat. No.: HY-I1196
Target:  

HCV

Research Areas:  

Infection

Sofosbuvir impurity L, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
loading...
    loading...
Cat. No.: HY-I0406
CAS No.: 1337482-17-3
Target:  

HCV

Research Areas:  

Infection

Sofosbuvir impurity F, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
loading...
    loading...
Cat. No.: HY-I0408
CAS No.: 1337482-15-1
Target:  

HCV

Research Areas:  

Others

Sofosbuvir impurity G, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
loading...
    loading...
Cat. No.: HY-I0938
CAS No.: 2225762-89-8
Target:  

HCV

Research Areas:  

Infection

Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
loading...
    loading...
Cat. No.: HY-I0975
CAS No.: 1334513-10-8
Target:  

HCV

Research Areas:  

Infection

Sofosbuvir impurity J, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
loading...
    loading...
Cat. No.: HY-10240R
CAS No.: 940908-79-2
Synonyms: RG 7128 (Standard); R-7128 (Standard); PSI 6130 diisobutyrate (Standard)
Target:  

Reference Standards HCV

Research Areas:  

Infection

Mericitabine (Standard) is the analytical standard of Mericitabine. This product is intended for research and analytical applications. Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.
loading...
    loading...
Cat. No.: HY-159153
Research Areas:  

Cancer

Photosensitizer-4 (compound PS-I) is a potent photosensitizer. Photosensitizer-4 effectively kills cancer cells and inhibits tumor growth under light irradiation .
loading...
    loading...
Cat. No.: HY-171362
CAS No.: 1015073-44-5
Target:  

Drug Metabolite

Research Areas:  

Infection

PSI-7410 is the metabolite of PSI-7851 (HY-14308). PSI-7851 is an inhibitor for HCV nonstructural protein 5B (NS5B) and exhibits antiviral activity .
loading...
    loading...
Cat. No.: HY-182565
CAS No.: 1854997-77-5
Target:  

Plasminogen/Plasmin

Research Areas:  

Cancer

PSI-112 is a YO-class μPlm inhibitor, with IC50 values of 0.38 μM, 1.48 μM and 0.37 μM against the wild-type, F587A mutant and K607A mutant, respectively. PSI-112 shows low affinity for uPA. PSI-112 can be used in cancer research .
loading...
    loading...
Cat. No.: HY-10165R
CAS No.: 817204-33-4
Synonyms: R 1656 (Standard)
Target:  

HCV Reference Standards

Research Areas:  

Infection

PSI-6130 (Standard) is the analytical standard of PSI-6130 (HY-10165). This product is intended for research and analytical applications. PSI-6130 is a potent and selective inhibitor of HCV NS5B polymerase, and inhibits HCV replication with a mean IC50 of 0.6 μM.
loading...
    loading...
Cat. No.: HY-N21824
CAS No.: 155158-70-6
(+)-(3S)-ψ-Ribalinine is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with an IC50 of 62.46 μM against electric eel acetylcholinesterase and an IC50 of 150.04 μM against equine butyrylcholinesterase. (+)-(3S)-ψ-Ribalinine can be used for the research of neurological disorders .
loading...
    loading...
Cat. No.: HY-N18959
CAS No.: 4586-65-6
Ψ-Taraxasterol acetate is a pentacyclic triterpene acetate that can be isolated from the kernel of Vitellaria paradoxa (shea tree) .
loading...
    loading...
loading...
    loading...
loading...
    loading...
Cat. No.: HY-E71275
Research Areas:  

Others

β-apo-4'-Carotenal oxygenase (EC 1.2.1.82) is an enzyme with systematic name 4'-apo-beta,psi-carotenal:NAD+ oxidoreductase.
loading...
    loading...
Cat. No.: HY-E71453T
Research Areas:  

Others

23S rRNA (pseudouridine1915-N3)-Methyltransferase (EC 2.1.1.177) specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
loading...
    loading...
Cat. No.: HY-P992396

Target:  

c-Met/HGFR

Research Areas:  

Cancer

KTN0073 is a high-affinity MET receptor tyrosine kinase inhibitor. KTN0073 can be used in studies related to non-small cell lung cancer and human cancers driven by HGF, MET amplification, or exon 14 mutation. KTN0073 binds to the Sema/PSI domain to block the HGF-MET interaction, and induces ubiquitination and degradation of oncogenic MET receptors via an HGF-independent pathway, thereby inhibiting MET-dependent signal transduction. KTN0073 exhibits significant antitumor activity in vivo, and its tumor suppressive activity is superior to that of the IgG1 subtype when grafted to the IgG2 constant region .
loading...
    loading...