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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
163 Results for "
enterococcus
" in MedChemExpress (MCE) Product Catalog:
Products (163)
163 Results for "enterococcus" in MCE Product Catalog:
Cat. No.: HY-161263
Antibacterial agent 182 (compound 8c) is an antibacterial agent that shows antibacterial activity against various Gram-positive bacteria, particularly against Vancomycin-resistant Enterococcus faecalis (MIC ≤0.125 μg/mL). Antibacterial agent 182 inhibits biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa at sub-MIC doses .
Cat. No.: HY-162429
Antibacterial agent 205 (Compound 10d) is a indolylacryloyl-derived oxacins, which exhibits broad antibacterial spectrum with MIC of 0.25-0.5 μg/mL. Antibacterial agent 205 reduces the exopolysaccharide, eliminates the biofilm, and thus attenuates the drug resistance. Antibacterial agent 205 exhibits antibacterial activity through destory of membrane integrity, accumulation of reactive oxygen species ROS, and inhibition of DNA replication .
Cat. No.: HY-162430
Antibacterial agent 206 (Compound 10e) is a indolylacryloyl-derived oxacins, which exhibits broad antibacterial spectrum with MIC of 0.25-1 μg/mL. Antibacterial agent 206 reduces the exopolysaccharide, eliminates the biofilm, and thus attenuates the drug resistance. Antibacterial agent 206 exhibits antibacterial activity through destory of membrane integrity, accumulation of reactive oxygen species ROS, and inhibition of DNA replication .
Cat. No.: HY-N7188
CAS No.: 405072-57-3
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Cat. No.: HY-N12320
CAS No.: 1596355-59-7
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Cat. No.: HY-173225
MRSA/VRE-IN-1 (Compound 3e) is an inhibitor against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). The MIC/MBC of MRSA/VRE-IN-1 against VRE is 3.6/7.3 µM, and against MRSA is 7.3/14.6 µM. MRSA/VRE-IN-1 can be used in the research of the anti-infection field .
Cat. No.: HY-N10561
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Cat. No.: HY-N14163
CAS No.: 220766-06-3
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Cat. No.: HY-13766A
CAS No.: 183313-30-6
Synonyms: VX-853-2
Timcodar mesylate (VX-853-2) and its analog VX-710 are mammalian multidrug-resistant bacterial efflux pump inhibitors that directly inhibit ethidium bromide efflux in Staphylococcus aureus. Timcodar mesylate has the potential to enhance antibiotic activity by inhibiting bacterial efflux pumps, effectively reducing the minimum inhibitory concentration of some antibiotics against Gram-positive pathogens such as Staphylococcus aureus, Enterococcus and Streptococcus pneumoniae .
Cat. No.: HY-N10560
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Cat. No.: HY-P5356
CAS No.: 97055-77-1
Synonyms: Plasmin substrate
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H-D-Val-Leu-Lys-AFC (Plasmin substrate) is a plasmin-specific fluorescent substrate. H-D-Val-Leu-Lys-AFC can be cleaved to generate a fluorescent signal, which is used to determine plasmin activity. Abs/Em=380/500 nm .
Cat. No.: HY-N6846
CAS No.: 22518-06-5
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Cat. No.: HY-E71010
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NADH Peroxidase, Enterococcus faecalis (EC 1.11.1.1) catalyzes the reversible conversion of NADH and hydrogen peroxide into NAD+ and water.
Cat. No.: HY-187666
CAS No.: 506429-34-1
YycG-IN-1 is a selective YycG inhibitor, with an IC50 of 42.9 μM and a Kd of 86.4 μM against YycG from Enterococcus faecalis. YycG-IN-1 inhibits the kinase activity and autophosphorylation activity of YycG, suppresses biofilm formation of Enterococcus faecalis, inhibits the planktonic growth of Enterococcus faecalis, and exerts effects on multiple mutant strains of Enterococcus faecalis. YycG-IN-1 can be used in studies related to Enterococcus faecalis infection .
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Methyl acetazolamide (Propazolamide) is a carbonic anhydrase inhibitor with Ki values of 37.5 nM against Enterococcus faecium α-CA, 250.1 nM against Enterococcus faecium γ-CA, 235.4 nM against human CA I, and 37.2 nM against human CA II. Methyl acetazolamide can be used for the research of enterococcus infections .
Cat. No.: HY-10391
CAS No.: 128311-86-4
E3709 is an antibacterial agent. E3709 exhibits significant inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA), Enterococcus faecalis, streptococci, Clostridia, and diphtheroids. E3709 can be used for research related to Gram-positive bacterial infections .
Cat. No.: HY-N19136
CAS No.: 163768-83-0
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Cat. No.: HY-187563
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RNP-11 is a selective COX-2 inhibitor with an IC50 of 42.85 μg/mL against human COX-2, and also acts as a bactericide and anti-inflammatory agent. RNP-11 inhibits the production of pro-inflammatory cytokines (IL-6, TNF-α, IL-1β, disrupts bacterial cell membranes and induces bacterial cell death. RNP-11 exhibits activity against strains of Staphylococcus and Enterococcus, including Methicillin (HY-121544)-resistant Staphylococcus aureus and Vancomycin (HY-B0671)-resistant Enterococcus faecium. RNP-11 reduces the load of Staphylococcus aureus, exerting dual effects of pathogen clearance and inflammatory response alleviation in a mouse skin infection model,. RNP-11 can be used in research related to infections caused by Staphylococcus, Staphylococcus aureus and Enterococcus faecium .
Cat. No.: HY-187641
CAS No.: 299419-24-2
ST056083 is a small-molecule inhibitor of the c-di-AMP synthase DisA. The apparent KD of ST056083 binding to DisA is 21 μM. ST056083 reduces c-di-AMP production in Enterococcus faecalis ATCC 29212, and inhibits bacterial growth, biofilm formation, bacterial viability within biofilms, and the synthesis of water-insoluble extracellular polysaccharides. ST056083 is applicable to studies on bacterial c-di-AMP signaling and E. faecalis-associated infections .
Cat. No.: HY-183459
CAS No.: 591207-81-7
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LB 11058 is a Cephalosporin Antibacterial agent. LB 11058 inhibits the growth of pathogenic bacteria, including multidrug-resistant staphylococci and streptococci, but shows weak activity against Enterococcus faecium, Corynebacterium species, Enterobacteriaceae and non-fermenting Gram-negative bacilli. LB 11058 can be used in bacterial infection research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
