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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
74 Results for "
nucleoside triphosphates
" in MedChemExpress (MCE) Product Catalog:
Products (74)
74 Results for "nucleoside triphosphates" in MCE Product Catalog:
Cat. No.: HY-N6666R
CAS No.: 24356-66-9
Research Areas:
Vidarabine monohydrate (Standard) is the analytical standard of Vidarabine monohydrate (HY-N6666). This product is intended for research and analytical applications. Vidarabine monohydrate is a Purine nucleoside derivative and Antiviral agent. The triphosphate derivative of Vidarabine monohydrate competitively inhibits DNA polymerase, incorporates into the terminus of elongating DNA molecules, and interferes with the early steps of viral DNA synthesis. Vidarabine monohydrate inhibits the replication of herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and vaccinia virus, reduces viral shedding, and accelerates skin healing. Vidarabine monohydrate is metabolized to arabinosyl hypoxanthine, causes minimal impairment of corneal wound healing in rabbit models, and is associated with recurrence of herpes simplex encephalitis. Vidarabine monohydrate can be used in the research of herpetic keratoconjunctivitis, herpes simplex encephalitis, herpetic uveitis, and chronic active hepatitis associated with hepatitis B virus .
Cat. No.: HY-131805A
Target:
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3'-O-Ac-dGTP sodium is an acetylated derivative of the nucleoside triphosphate 2'-deoxyguanosine-5'-triphosphate .
Cat. No.: HY-134278A
Synonyms: 8-Br-ITP tetrasodium; 8-Bromo ITP tetrasodium
Target:
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8-Bromoinosine-5'-O-triphosphate (8-Br-ITP) tetrasodium is a derivative of the nucleoside triphosphate Inosine-5'-triphosphate (ITP) (HY-W013706). 8-Bromoinosine-5'-O-triphosphate tetrasodium can be used in the determination of nucleoside diphosphate kinase (NDPK) activity .
Cat. No.: HY-131806A
Target:
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3'-O-Ac-dTTP sodium is an acetylated derivative of nucleoside 5′-triphosphate .
Cat. No.: HY-157263
CAS No.: 1117893-11-4
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dNaMTP is an unnatural nucleoside triphosphate. dNaMTP forms an unnatural base pair (UBP) and expands the genetic alphabet .
Cat. No.: HY-157264
CAS No.: 1472655-21-2
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dTPT3TP is a non-natural nucleoside triphosphate. dTPT3TP can be used by TdT to extend ssDNA primers .
Cat. No.: HY-E71013
Target:
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Nucleoside monophosphate kinase, Bovine (EC 2.7.4.6) is an enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. Nucleoside monophosphate kinase, Bovine (EC 2.7.4.6) activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when GTP produced in the citric acid (Krebs) cycle is converted to ATP.
Cat. No.: HY-137692A
Synonyms: ddUTPαS tetrasodium
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2',3'-Dideoxyuridine-5'-O-(1-thiotriphosphate) (ddUTPαS) tetrasodium is a sulfur-containing nucleoside triphosphate derivative .
Cat. No.: HY-172731
CAS No.: 3056945-23-1
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8-Oxo-dATP lithium, as an oxidized purine nucleoside triphosphate, is hydrolyzed by MTH1 into monophosphates, thereby preventing errors caused by its misincorporation during DNA replication or transcription .
Cat. No.: HY-E71558
Target:
Research Areas:
2-Hydroxy-dATP diphosphatase (EC 3.6.1.56) hydrolyses oxidized purine nucleoside triphosphates such as 2-hydroxy-dATP, thereby preventing their misincorporation into DNA, and can also recognize 8-oxo-dGTP and 8-oxo-dATP.
Cat. No.: HY-181481
Target:
Research Areas:
2'-Deoxyadenosine-5'-O-diphosphoribose sodium is a TRPM2 agonist. 2'-Deoxyadenosine-5'-O-diphosphoribose sodium enhances calcium-induced currents in inside-out patch-clamp experiments using HEK293 cells expressing human TRPM2. 2'-Deoxyadenosine-5'-O-diphosphoribose sodium is a substrate for Nucleoside Triphosphate Diphosphatase 9 (NUDT9) .
Cat. No.: HY-187164
CAS No.: 78945-99-0
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HCV NS5B polymerase-IN-5 is a HCV NS5B polymerase inhibitor with an IC50 value of 47.9 μM. HCV NS5B polymerase-IN-5 reduces the production of inorganic pyrophosphate and decreases the nucleoside triphosphate incorporation of HCV NS5B polymerase. HCV NS5B polymerase-IN-5 can be used in studies related to hepatitis C virus infection .
Cat. No.: HY-103263R
CAS No.: 1052089-16-3
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
PSB-06126 (Standard) is the analytical standard of PSB-06126 (HY-103263). This product is intended for research and analytical applications. PSB-06126 is a selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with the Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2 and 2.22 μM for NTPDase 3, respectively. PSB-06126 acts on human NTPDase 3 with an IC50 value of 7.76 μM and a Ki value of 4.39 μM .
Cat. No.: HY-185215
CAS No.: 1770840-57-7
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GS-646089 is a broad-spectrum antiviral nucleoside analog that exhibits significant inhibitory activity against respiratory syncytial virus (RSV), human metapneumovirus (hMPV), rhinovirus (enterovirus) and enteroviruses. The IC50 of GS-646089 targeting RNA-dependent RNA polymerase (RdRp) ranges from 43 to 46 nM. GS-646089 blocks viral replication by being converted into a triphosphate metabolite intracellularly, which competes with ATP for incorporation into nascent RNA strands and acts as an immediate chain terminator. GS-646089 is the parent compound of the double prodrug GS-7682 (HY-161877), and is used in studies of acute respiratory viral infections and infections caused by related pathogens .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
