909 Results for "

Cell-Surface

" in MedChemExpress (MCE) Product Catalog:
Products (909)

909 Results for "Cell-Surface" in MCE Product Catalog:

Cat. No.: HY-P86715
Synonyms: CD8 antigen, alpha polypeptide(p32); CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T Cell antigen; p32; T Cell antigen Leu2; T Cell co receptor; T-Cell Surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T Cell antigen.

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P705298
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD1D; HMC Class I Antigen-Like Glycoprotein CD1D; CD1d Molecule; T-Cell Surface Glycoprotein CD1d; Antigen-Presenting Glycoprotein CD1d; Thymocyte Antigen CD1D; CD1D Antigen, D Polypeptide; CD1d; CD1d Antigen; R3; R3G1; B2M; Beta 2-Microglobulin; Beta-2-M
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P89395M
Synonyms: CD8 antigen, alpha polypeptide(p32); CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T Cell antigen; p32; T Cell antigen Leu2; T Cell co receptor; T-Cell Surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T Cell antigen.

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-168384
CAS No.: 875158-73-9
M04 is an agonist of STING. It induces the expression of the IFN reporter gene in HEK293T cells expressing wild-type human STING, but does not induce this expression in HEK293T cells expressing the R71H-G230A-R293Q (HAQ) STING variant or in mouse RAW 264.7 cells, indicating that its activity is dependent on allelic and species variations. M04 induces the production of TNF-α, IL-10, IL-1β, and IL-12p70 in human peripheral blood mononuclear cells (PBMCs). At a concentration of 50 µM, M04 stimulates dendritic cells isolated from PBMCs to express the MHC class II cell surface receptor HLA-DR and co-stimulatory molecules CD40, CD80, and CD86, and also enhances their ability to activate T cells in an ex vivo assay. M04 can be used in research on inflammatory immune diseases .
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Cat. No.: HY-P81132
Synonyms: CD90 / Thy1; CD7; CD90 antigen; CDw90; FLJ33325; MGC128895; T25; Theta antigen; Thy-1; Thy 1; Thy 1 Cell Surface antigen; Thy-1 membrane glycoprotein; Thy 1 membrane glycoprotein precursor; Thy 1.2; Thy-1 T-Cell antigen; Thy1 antigen; Thy1 T Cell antigen; Thy1.1; Thy1.2; Thymus Cell antigen 1, theta; THY1_RAT; THY1_HUMAN.

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-P86708
Synonyms: BB2; CD54 antigen; CD54; ICAM1; ICAM 1; ICAM-1; Cell Surface glycoprotein P3.58; Human rhinovirus receptor; InterCellular adhesion molecule 1; Major group rhinovirus receptor; MALA2; MyD10; P3.58; Surface antigen of activated B Cells; ICAM1_HUMAN; MALA-2; MyD10; interCellular adhesion molecule 1 precursor; interCellular adhesion molecule 1(CD54), human rhinovirus receptor; major group rhinovirus receptor.

Host:  

Mouse

Application:  

IHC-P, IHC-F, IF-Tissue

Reactivity:  

Human

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Cat. No.: HY-P86708A
Synonyms: BB2; CD54 antigen; CD54; ICAM1; ICAM 1; ICAM-1; Cell Surface glycoprotein P3.58; Human rhinovirus receptor; InterCellular adhesion molecule 1; Major group rhinovirus receptor; MALA2; MyD10; P3.58; Surface antigen of activated B Cells; ICAM1_HUMAN; MALA-2; MyD10; interCellular adhesion molecule 1 precursor; interCellular adhesion molecule 1(CD54), human rhinovirus receptor; major group rhinovirus receptor.

Host:  

Mouse

Application:  

IHC-P, IHC-F, IF-Tissue

Reactivity:  

Human

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Cat. No.: HY-P705292
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD8A; Leu2 T-Lymphocyte Antigen; Prev. CD8; T-Cell Antigen Leu2; T-Cell Surface Glycoprotein CD8 Alpha Chain; T Cell Co-Receptor; T-Lymphocyte Differentiation Antigen T8/Leu-2; T8 T-Cell Antigen; CD8alpha; CD8a Antigen; P32; IMD116; CD8 Antigen, Alpha Polypeptide (P32); Leu2; CD8a Molecule; MAL; CD8 Subunit Alpha; OKT8 T-Cell Antigen
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-164729
FZ-AD005 is a DLL3-targeting antibody-drug conjugate (ADC) with high selectivity, composed of the anti-DLL3 antibody FZ-A038 (HY-P990896), a dipeptide linker (Val-Ala), and DXd (HY-13631D). The Kd value of FZ-AD005 for human DLL3 ranges from 13.29 to 58.3 pmol/L. After binding to DLL3 on the cell surface, FZ-AD005 mediates endocytosis, and the payload DXd is released via cleavage by lysosomal cathepsins. DXd inhibits topoisomerase TopI to induce double-strand DNA breaks, cell cycle arrest and apoptosis, and FZ-AD005 exhibits bystander killing activity against adjacent DLL3-negative cells. FZ-AD005 shows stable circulation in vivo, has good tolerance and acceptable pharmacokinetic profiles in rats and cynomolgus monkeys, and effectively inhibits the growth of DLL3-expressing tumor cells. FZ-AD005 serves as a promising candidate molecule for research on small cell lung cancer and human neuroendocrine prostate cancer .
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Cat. No.: HY-B0633D
CAS No.: 9067-32-7
Hyaluronic acid sodium (MW 200-1560) is a biopolymer composed of repeating disaccharide units, with a molecular weight of 200-1560. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid sodium exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid sodium activates PI3K-Akt signaling. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid sodium is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid sodium can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid sodium can lubricate the corneal endothelium. Hyaluronic acid sodium can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid sodium has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid sodium can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .
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Cat. No.: HY-B0633E
CAS No.: 9004-61-9
Synonyms: Hyaluronan, low endotoxin; Hyaluronate, low endotoxin
Hyaluronic acid, low endotoxin (Hyaluronan, low endotoxin) is a biopolymer composed of repeating disaccharide units containing low levels of endotoxin. Hyaluronic acid is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid activates PI3K-Akt signaling. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid can lubricate the corneal endothelium. Hyaluronic acid can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .
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Cat. No.: HY-P85834
Synonyms: ADMCKD; ADMCKD1; Breast carcinoma associated antigen DF3; Breast carcinoma-associated antigen DF3; CA 15-3; CA15 3; CA15 3 antigen; CA15-3; CA15.3; Cancer antigen 15-3; Carcinoma associated mucin; Carcinoma-associated mucin; CD 227; CD227; DF3 antigen; EMA; Episialin; Epithelial Membrane Antigen; H23 antigen; H23AG; KL 6; KL-6; KL6; Krebs von den Lungen-6; MAM 6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease 1; autosomal dominant; Medullary cystic kidney disease, autosomal dominant; MUC 1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; MUC1_HUMAN; Mucin 1; Mucin 1 Cell Surface associated; Mucin 1 transmembrane; Mucin 1, Cell Surface associated; Mucin-1 subunit beta; Peanut reactive urinary mucin; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor associated epithelial membrane antigen; Tumor associated epithelial mucin; Tumor associated mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin

Host:  

Mouse

Application:  

IHC-P, WB, ICC/IF, ELISA

Reactivity:  

Human

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Cat. No.: HY-165613
CAS No.: 656831-18-4
Synonyms: Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine
Pam2Cys (Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine) is a TLR2 agonist and immunostimulant. Pam2Cys binds to TLR2 to activate dendritic cells and trigger the TLR2-dependent NF-κB signaling pathway. Pam2Cys also induces dendritic cell maturation by upregulating the expression of cell surface MHC II molecules. Pam2Cys activates innate immune signaling pathways, drives pro-inflammatory and antimicrobial responses, enhances the expression of macrophage activation markers, increases phagocytic activity, induces the release of IL-12 and pro-inflammatory cytokines, and polarizes macrophages into a pro-inflammatory, antimicrobial phenotype without interfering with IL-10-induced macrophage polarization. Pam2Cys also serves as the lipid moiety in synthetic lipopeptide vaccines and possesses self-adjuvant properties. Pam2Cys enhances the immunogenicity of conjugated peptide segments and induces cellular and humoral immune responses. However, it does not activate CD4 T cells in mouse splenocyte cultures when used alone. Pam2Cys activates pulmonary TLR2 signaling pathways, triggers innate immune responses, recruits neutrophils and macrophages, induces the secretion of various cytokines, alleviates symptoms and damages associated with influenza A virus infection in mice without impairing adaptive immunity. Pam2Cys can be used in studies related to tuberculosis and influenza A virus infection .
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Cat. No.: HY-P70857
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; Receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SErbB3; HER3; P85-SErbB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ErbB-3 R31; Tyrosine Kinase-Type Cell Surface Receptor HER3; MDA-BF-1; Human Epidermal Growth Factor Receptor 3; C-ErbB3; Receptor Tyrosine-Protein Kinase ErbB-3; ErbB3-S; Proto-Oncogene-Like Protein C-ErbB-3; ErbB-3; C-ErbB-3; FERLK; CDNA FLJ43038 Fis, Clone BRTHA3002955, Highly Similar To Receptor Tyrosine-Protein Kinase ErbB-3; VSCN1; Lethal Congenital Contracture Syndrome 2; Erb-B2 Receptor Tyrosine Kinase 3; P180-ErbB3
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P74894
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; Receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SErbB3; HER3; P85-SErbB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ErbB-3 R31; Tyrosine Kinase-Type Cell Surface Receptor HER3; MDA-BF-1; Human Epidermal Growth Factor Receptor 3; C-ErbB3; Receptor Tyrosine-Protein Kinase ErbB-3; ErbB3-S; Proto-Oncogene-Like Protein C-ErbB-3; ErbB-3; C-ErbB-3; FERLK; CDNA FLJ43038 Fis, Clone BRTHA3002955, Highly Similar To Receptor Tyrosine-Protein Kinase ErbB-3; VSCN1; Lethal Congenital Contracture Syndrome 2; Erb-B2 Receptor Tyrosine Kinase 3; P180-ErbB3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P706044
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ERBB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180erbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 4; V-Erb-A Erythroblastic Leukemia Viral Oncogene Homolog 4; Tyrosine Kinase-Type Cell Surface Receptor HER4; Receptor Protein-Tyrosine Kinase; Human Epidermal Growth Factor Receptor 4; Uncharacterized Protein ERBB4; Receptor Tyrosine-Protein Kinase ErbB-4; Alternative Protein ERBB4
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P83741
Synonyms: 17 1A antibody; 323/A3 antibody; Adenocarcinoma associated antigen antibody; Antigen identified by monoclonal antibody; AUA1 antibody; CD326 antibody; Cell Surface glycoprotein Trop 1 antibody; CO17A antibody; DIAR5 antibody; EGP 2 antibody; EGP antibody; EGP2 antibody; EGP314 antibody; EGP40 antibody; EPCAM antibody; Epithelial Cell adhesion molecule antibody; ESA antibody; GA733 1 antibody; gp4 antibody; hEGP 2 antibody; hEGP314 antibody; HNPCC8 antibody; KS1/4 antibody; KSA antibody; Ly74 antibody; M1S 1 antibody; M1S2 antibody; M4S1 antibody; mEGP314 antibody; MIC18 antibody; MK 1 antibody; Protein 289A antibody; TACD1 antibody; TACSTD1 antibody; TROP1 antibody

Host:  

Rabbit

Application:  

IHC-P, ICC/IF, FC

Reactivity:  

Human

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Cat. No.: HY-P86719
Synonyms: Erb-B2 Receptor Tyrosine Kinase 2; NGL; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; Tyrosine Kinase-Type Cell Surface Receptor HER2; Neuro/Glioblastoma Derived Oncogene Homolog; Human Epidermal Growth Factor Receptor 2; Metastatic Lymph Node Gene 19 Protein; Proto-Oncogene C-ErbB-2; Proto-Oncogene Neu; EC 2.7.10.1; P185erbB2; MLN 19; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Receptor Tyrosine-Protein Kinase ErbB-2; C-Erb B2/Neu Protein; CD340 Antigen; Herstatin; EC 2.7.10; CD340; HER-2; MLN19; TKR1;

Host:  

Mouse

Application:  

WB, IHC-P, IHC-F, IF-Tissue

Reactivity:  

Human

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Cat. No.: HY-P86719A
Synonyms: Erb-B2 Receptor Tyrosine Kinase 2; NGL; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; Tyrosine Kinase-Type Cell Surface Receptor HER2; Neuro/Glioblastoma Derived Oncogene Homolog; Human Epidermal Growth Factor Receptor 2; Metastatic Lymph Node Gene 19 Protein; Proto-Oncogene C-ErbB-2; Proto-Oncogene Neu; EC 2.7.10.1; P185erbB2; MLN 19; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Receptor Tyrosine-Protein Kinase ErbB-2; C-Erb B2/Neu Protein; CD340 Antigen; Herstatin; EC 2.7.10; CD340; HER-2; MLN19; TKR1;

Host:  

Mouse

Application:  

WB, IHC-P, IHC-F, IF-Tissue

Reactivity:  

Human

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Cat. No.: HY-P705359
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HLA-A; MHC Class 1 Antigen; Major Histocompatibility Complex, Class I, A; MHC ClassI Antigen; HLA Class I Histocompatibility Antigen, A Alpha Chain; Lymphocyte Antigen; MHC Class I Antigen HLA-A Heavy Chain; HLA-A*6602 Antigen; Leukocyte Antigen Class I-A; HLA-Aw34.2 Antigen; HLAA; HLA-A-6802 Protein; Major Histocompatibility Complex Class I HLA-A-32 Protein; HLA-A-0203 Protein; HLA Class I Histocompatibility Antigen, A-1 Alpha Chain; MHC Class1 Antigen; HLA Class I Histocompatibility Antigen A Alpha Chain; Leukocyte Antigen; Signal Peptide Alpha1 And Alpha2 Domain; HLA-A26.4 Antigen; HLA Class I Histocompatibility Antigen; HLA-A10SA Antigen; MHC HLA-A Cell Surface Glycoprotein; MHC Class I HLA-A; HLA Class I A Locus Antigen A*68new; HLA-A26.3 Antigen; MHC Class I Human Leukocyte Antigen; HLA-A30.2 Antigen; Ig-Like Domain-Containing Protein; HLA-A2new Protein; MHC Class I Antigen Null Protein; Leucocyte Antigen; HLA-A Alpha1 And Alpha2 Domains; HLA-A9HH Antigen; MHC Class I Antigen Heavy Chain; MHC Class I Anti; Leucocyte Antigen A Alpha Chain; HLA-A29 Variant; Truncated MHC Class I Antigen; HLA-A25 Protein; Truncated MHC Class I Protein; MHC Alpha Chain; MHC Class I Antigen Precusor; HLA-A*02:01NEW; MHC Class I Protein (HLA-A); HLA-A Protein; HLA-A Locus Alpha 2 Domain; HLA Class I A; Lymphocyte Antigen M7-A2.2; Alpha1 Domain; MHC Class I Antigen R69772; MHC Class I; Human Leukocyte Antigen A; HLA-A*24var; HLA-A*24:02:01:01 Variant; HLA-A*0210; MHC Class I Antigen HLA-A; HLA-A*2903; Cell Surface Glycoprotein; HLA-A-6802; Leucocyte Antigen Class I; HLA-A-0203; Leukocyte Antigen Class I; HLA-A*3303; Transplantation Antigen; HLA-A*0218; HLA Class I Heavy Chain; HLA-A2 SLU; HLA-A11 Antigen A11.2; HLA-A-02; MHC Class I Antigen A; HLA-A-32; MHC Leukocyte Antigen; HLA-A30; MHC Class II Antigen; HLA-A25; MHC Class I Antigene; HLA-A26; Cell Surface Antigen; HLA-A*; HLA-A Alpha 1 Domain; HLA-A2; MHC Class I Antigen; A1102; MHC Class I Protein; Hla-A; HLA Class I Antigen; HLA-H; Leucocyte Antigen A; HLA_A; MCH Class I Antigen; HLA; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr Beta Chain
Species:  
Human
Source:  
HEK293
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