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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
91 Results for "
Antituberculosis activity
" in MedChemExpress (MCE) Product Catalog:
Products (91)
91 Results for "Antituberculosis activity" in MCE Product Catalog:
Cat. No.: HY-N19992
Synonyms: Rabdosia serra extract
Cat. No.: HY-184411
CAS No.: 3104768-44-4
TB-212 is a potent, orally active anti-tuberculosis agent. TB-212 exhibits activity against both drug-susceptible and drug-resistant Mycobacterium tuberculosis strains, with favorable safety profiles. TB-212 is applicable to the research of tuberculosis .
Cat. No.: HY-N9229
CAS No.: 1612239-23-2
Cat. No.: HY-W013677S1
CAS No.: 285977-82-4
Cat. No.: HY-173205
Antimycobacterial agent - 11 (Compound QM7) is a bacteriostatic agent with anti-tuberculosis activity. Its minimum inhibitory concentration (MIC) against Mycobacterium tuberculosis (Mtb) is 5.58 μg/mL. Antimycobacterial agent - 11 can be used in the research of the anti - infection field, especially in the field of tuberculosis .
Cat. No.: HY-129819
CAS No.: 1333170-15-2
(Rac)-DNDI-8219 is an antituberculosis compound with potent anti-leishmanial activity. (Rac)-DNDI-8219 demonstrated superior efficacy in the Leishmania donovani mouse model. (Rac)-DNDI-8219 showed promising activity in the Leishmania infantum hamster model. (Rac)-DNDI-8219 candidate compound R-6 provided excellent oral efficacy in the same hamster model .
Cat. No.: HY-134940S1
Synonyms: OPC-167832-d4
Cat. No.: HY-187375
Target:
Research Areas:
DL25 is a fungicide with an IC50 of 5.0 μg/mL against Mycobacterium tuberculosis DHQS. DL25 binds with high affinity to mycobacterial targets LysA, LpdA and SecA1. DL25 exhibits broad-spectrum anti-mycobacterial activity against multiple mycobacterial species and shows partial synergy with established anti-tuberculosis drugs. DL25 can be used in studies related to tuberculosis .
Cat. No.: HY-183688
CAS No.: 3104354-58-4
Target:
Research Areas:
MptpB-IN-3 is a selective inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) with an IC50 of 0.19 μM. MptpB-IN-3 blocks MptpB-mediated inhibition of the macrophage MAPK pathway and restores the phosphorylation levels of Erk1/2 and p38. MptpB-IN-3 exhibits direct anti-tuberculosis activity against Mycobacterium tuberculosis and reduces the Mycobacterium tuberculosis load in mouse macrophages. MptpB-IN-3 can be used for tuberculosis research .
Cat. No.: HY-201256
CAS No.: 301312-49-2
UCI-14 is a gltA1/lprQ modulator with in vitro anti-tuberculosis activity against drug-sensitive and multidrug-resistant mycobacteria. UCI-14 upregulates the expression of genes encoding citrate synthase I, downregulates the expression of genes encoding conserved mycobacterial lipoprotein, and alters the carbon metabolism of mycobacteria. UCI-14 reactivates the expression of wild-type p53 target genes in p53-mutated cells. UCI-14 can be used in the research of tuberculosis and cancer .
Cat. No.: HY-179529
EGFR/InhA-IN-1 (Compound 15) is an inhibitor of the anti-cancer target EGFR tyrosine kinase (1M17) (Ki = 0.05 μM) and the anti-tuberculosis target InhA enzyme (1OUZ) (Ki = 0.02 μM). EGFR/InhA-IN-1 exhibits anti-proliferative activity against A549 cells, with an IC50 of 10.38 μM. EGFR/InhA-IN-1 has inhibitory activity against Mycobacterium tuberculosis H37Rv, with a MIC of 6.25 μM. EGFR/InhA-IN-1 can be used for research on non-small cell lung cancer and Mycobacterium tuberculosis infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
