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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
93 Results for "
antibioti
" in MedChemExpress (MCE) Product Catalog:
Products (93)
93 Results for "antibioti" in MCE Product Catalog:
Cat. No.: HY-106289
CAS No.: 105026-50-4
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Antibiotic MX 2 is an orally active antibiotic that can cross the blood-brain barrier. Antibiotic MX 2 inhibits the growth of drug-sensitive and multidrug-resistant tumor cells, prolongs the survival of tumor-bearing mice, induces single-strand and double-strand DNA breaks, suppresses colony formation of fresh human-derived tumor cells, and overcomes multidrug resistance mediated by P-glycoprotein. Antibiotic MX 2 can be used in research related to L1210 leukemia, Lewis lung cancer, colon adenocarcinoma type 26 and type 38, gastric adenocarcinoma, non-small cell lung cancer, mammary adenocarcinoma, drug-resistant P388 leukemia, renal cancer, melanoma, ovarian cancer, breast cancer, small cell lung cancer, and colorectal cancer .
Cat. No.: HY-L067
748 compounds
Antibiotics are types of antimicrobial products used for the treatment and prevention of bacterial infections. Antibiotics can kill or inhibit bacterial growth. Although the target of an antibiotic is bacteria, some antibiotics also attack fungi and protozoans. However, antibiotics rarely have an effect on viruses. The major mechanism underlying antibiotics is the inhibition or regulation of enzymes involved in cell wall biosynthesis, nucleic acid metabolism and repair, protein synthesis, or disruption of membrane structure. Many of these cellular functions targeted by antibiotics are most active in multiplying cells. Since there is often overlap in these functions between prokaryotic bacterial cells and eukaryotic mammalian cells, it is not surprising that some antibiotics have also been found to be useful as anticancer agents.
MCE supplies a unique collection of 748 antibiotics, including penicillins, cephalosporins, tetracyclines, macrolides, etc. MCE Antibiotics Library is a useful tool for anti-bacterial or anti-cancer drugs discovery.
Cat. No.: HY-181935
CAS No.: 2493985-50-3
Antibiotic adjuvant 4 (Compound 13) is an Antibiotic adjuvant and efflux pump inhibitor. Antibiotic adjuvant 4 exhibits potent efflux pump inhibitory activity. Antibiotic adjuvant 4 significantly downregulates virulence-related genes of Staphylococcus aureus when used alone or in combination with antibiotics. Antibiotic adjuvant 4 enhances the efficacy of Ciprofloxacin (HY-B0356) against multiagent-resistant Staphylococcus aureus strains .
Cat. No.: HY-182675
CAS No.: 2292113-87-0
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Antibiotic adjuvant 5 (Compound 2) acts as an Antibiotic adjuvant. Antibiotic adjuvant 5 enhances the activity of Azithromycin (HY-17506), Clarithromycin (HY-17508), Doripenem (HY-B0187) and Rifampin (HY-B0272) against *Pseudomonas aeruginosa* PAO1. When used in combination with Azithromycin, Antibiotic adjuvant 5 increases the survival rate of *Galleria mellonella* during *Pseudomonas aeruginosa* PAO1 infection. Antibiotic adjuvant 5 is applicable for the research of *Pseudomonas aeruginosa* infection .
Cat. No.: HY-N19237
CAS No.: 83917-57-1
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Cat. No.: HY-106590
CAS No.: 86630-31-1
Synonyms: antibiotic KA 5685
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Cat. No.: HY-111221
CAS No.: 87860-38-6
Synonyms: antibiotic CL 1565T; CL 1565T
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PD 113271 is an active compound.
Cat. No.: HY-103397AR
CAS No.: 98392-26-8
Synonyms: antibiotic YS-02931K-β (Standard)
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Dihydrokalafungin (Standard) is the analytical standard of Dihydrokalafungin (HY-103397A). This product is intended for research and analytical applications. Dihydrokalafungin (Antibiotic YS-02931K-β) is a benzoisochromanequinone that used as a natural substrate in enzyme assays of the ActVB-ActVA system .
Cat. No.: HY-N1724B
CAS No.: 80890-47-7
Synonyms: antibiotic X 4357B (purity≥90%); Folimycin (purity≥90%); X 4357B (purity≥90%)
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Cat. No.: HY-108718R
CAS No.: 49863-47-0
Synonyms: Geneticin (Standard); antibiotic G-418 (Standard)
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G-418 (Standard) is the analytical standard of G-418 (HY-108718). This product is intended for research and analytical applications. G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .
Cat. No.: HY-101938R
CAS No.: 58944-73-3
Synonyms: Adenosyl-Ornithine (Standard); A-9145 (Standard); antibiotic 32232RP (Standard)
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Sinefungin (Standard) is the analytical standard of Sinefungin (HY-101938). This product is intended for research and analytical applications. Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication . Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation .
Cat. No.: HY-B1071B
CAS No.: 33855-11-7
Synonyms: Lasalocid-A ammonium; Ionophore X-537A ammonium; antibiotic X-537A ammonium
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Cat. No.: HY-N6687C
Synonyms: A-23187 quartercalcium quartermagnesium; antibiotic A-23187 quartercalcium quartermagnesium
Calcimycin (A-23187) hemicalcium hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemicalcium hemimagnesium induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemicalcium hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemicalcium hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemicalcium hemimagnesium induces apoptosis and autophagy .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
