91 Results for "

hydrated matrices

" in MedChemExpress (MCE) Product Catalog:
Products (91)

91 Results for "hydrated matrices" in MCE Product Catalog:

Cat. No.: HY-N19343
CAS No.: 94492-22-5
Cistanoside C is a phenylpropanoid glycoside with free radical scavenging, DNA repair and DNA minor groove binding activities. Cistanoside C scavenges hydrated electrons and hydroxyl radicals. Cistanoside C inhibits the proliferation of cancer cells. Cistanoside C can be used in research related to leukemia, liver cancer, lung adenocarcinoma and gastric adenocarcinoma .
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Cat. No.: HY-187855
CAS No.: 17364-19-1
Synonyms: 18:0-LPC
1-Stearoyl-lysophosphatidylcholine (18:0-LPC) is a lysophosphatidylcholine generated by iPLA2β-mediated hydrolysis of phosphatidylcholine and present in circulating LDL; under different hydration conditions, it can form a bilayer gel phase, bilayer liquid crystalline phase, or micellar phase, and serves as a key metabolic node in the JSRV-induced OPA protein-metabolite network. 1-Stearoyl-lysophosphatidylcholine can be used in research on nonalcoholic steatohepatitis and ovine pulmonary adenocarcinoma .
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Cat. No.: HY-W108862
CAS No.: 66204-44-2
Target:  

Bacterial

Research Areas:  

Infection

3,3'-Methylenebis[5-methyloxazolidine] is a bisoxazolidine-based hydrogen sulfide scavenger and fungicide derived from monoisopropanolamine (MIPA). 3,3'-Methylenebis[5-methyloxazolidine] exists as a mixture of structural isomers. 3,3'-Methylenebis[5-methyloxazolidine] is oil-soluble and serves as an oil-soluble alternative to hydrated hexahydrotriazine-based scavengers. 3,3'-Methylenebis[5-methyloxazolidine] can scavenge hydrogen sulfide and methanethiol via chemical reactions, and its scavenging efficiency increases after hydrolysis to MIPA-triazine in water .
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Cat. No.: HY-L098
440 compounds

A drug metabolite is a byproduct of the body breaking down, or “metabolizing” a drug into a different substance. Most drugs undergo chemical alteration by various bodily systems as a way to create compounds that are more easily excreted from the body. Drugs can be metabolized by oxidation, reduction, hydrolysis, hydration, conjugation, condensation, or isomerization. Drug metabolism can produce metabolites with physicochemical and pharmacological properties that differ substantially from those of the parent drug, and consequently have important implications for both drug safety and efficacy.

MCE offers a unique collection of 440 drug metabolites which is a useful tool for drug safety and efficacy study and drug repurposing.

Cat. No.: HY-79587
CAS No.: 134-81-6
Research Areas:  

Others

Benzil is a 1,2-diketone compound with multiple functions including photo-peroxidation initiator, crosslinking initiator and pattern-forming agent, and is commonly used as a precursor for photodegradable network crosslinkers. In oxygen-purged polymer films or glassy matrices, Benzil reacts with molecular oxygen under illumination at wavelengths greater than 370 nm or 400 nm, and converts to benzoyl peroxide in nearly quantitative yield. Subsequently, the generated benzoyl peroxide groups produce free radicals via thermal or photochemical decomposition, thereby enabling crosslinking of polymer chains, grafting of new monomers, and preparation of patterned polymers on solid surfaces using mask irradiation. Benzil also induces crosslinking of photodegradable poly (phenyl vinyl ketone) to form a stable photodegradable polymer network .
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Cat. No.: HY-184870
CAS No.: 31621-87-1
Target:  

Others

Research Areas:  

Inflammation/Immunology

Polydioxanone is a colorless, crystalline semi-crystalline thermoplastic poly (ether-ester) bioabsorbable polymer. Polydioxanone serves as a hemostatic agent, biodegradable agent, degradant, lumen patency maintainer, as well as a temporary inducer of tracheal tissue injury and inflammation. Polydioxanone controls bone bleeding in biocompatible matrices, degrades via random hydrolytic scission and end-chain scission, with accelerated degradation occurring at pH <1.67, maintains tracheal lumen patency, and induces reversible tracheal epithelial necrosis, inflammation, fibrous tissue hyperplasia, and goblet cell hyperplasia. Polydioxanone can be used in research on bone bleeding, non-malignant tracheal stenosis, tracheobronchial stenosis, tracheobronchomalacia, and airway obstruction associated with vascular compression .
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Cat. No.: HY-W016589
CAS No.: 1879-09-0
Synonyms: 6-tert-Butyl-2,4-xylenol
2-(tert-Butyl)-4,6-dimethylphenol (6-tert-Butyl-2,4-xylenol) is an electrophilic alkylating agent, gasoline antioxidant and hydration substrate. 2-(tert-Butyl)-4,6-dimethylphenol inhibits SERCA activity in rabbit hindleg microsomes with an IC50 of 53 μM. Oxidation of 2-(tert-Butyl)-4,6-dimethylphenol generates the intermediate BDMP-QM, which covalently modifies nitrogen sites of proteins, polypeptides and free amino acids via Michael addition, triggering covalent modification of macromolecules and mediating cytotoxicity. 2-(tert-Butyl)-4,6-dimethylphenol is widely used in toxicological and biochemical studies of alkylphenols .
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Cat. No.: HY-108036AR
CAS No.: 868156-46-1
Synonyms: (S)-Hydroxypropyl tetrahydropyrantriol (Standard)
(S)-Pro-xylane (Standard) is the analytical standard of (S)-Pro-xylane (HY-108036A). This product is intended for research and analytical applications. (S)-Pro-xylane ((S)-Hydroxypropyl tetrahydropyrantriol) is a bioactive C-glycoside that targets the biosynthesis pathway of glycosaminoglycans/mucopolysaccharides (GAGs) in the sKin matrix and can be absorbed transdermally. (S)-Pro-xylane stimulates the biosynthesis of GAGs in fibroblasts, enhances the structural stability of the sKin extracellular matrix, improves sKin elasticity and moisturizing ability, and delays wrinkle formation. (S)-Pro-xylane can effectively promote the synthesis of collagen fibers and hyaluronic acid in the dermis. (S)-Pro-xylane is used in the field of anti-aging cosmetics to improve sKin hydration and elasticity. (S)-Pro-xylane is eco-friendly and biodegradable .
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Cat. No.: HY-N21668
CAS No.: 114297-65-3
6-O-(E)-p-Hydroxy-cinnamoyl-glucose is a phenylpropanoid glycoside isolated from Aristolochia manshuriensis Kom., acting as a free radical scavenger. 6-O-(E)-p-Hydroxy-cinnamoyl-glucose scavenges hydrated electrons, sulfate radical anions, and hydroxyl radicals by forming phenoxyl radicals at its conjugated carbonyl/keto group. 6-O-(E)-p-Hydroxy-cinnamoyl-glucose repairs oxidative DNA damage, DNA radical cations and anions, as well as deoxynucleotide radical cations (dAMP, dGMP, dCMP) and anions through electron transfer. 6-O-(E)-p-Hydroxy-cinnamoyl-glucose is useful for research on DNA damage-related diseases .
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Cat. No.: HY-D3090
CAS No.: 2757682-04-3
Target:  

Fluorescent Dye

Research Areas:  

Others

NRLD is a lipid droplet-targeting solvatochromic fluorescent probe developed based on Nile Red (HY-D0718), which can target lipid droplets and sense the non-polar lipid microenvironment inside lipid droplets. NRLD exhibits superior lipid droplet-targeting selectivity compared to the parent Nile Red dye in HeLa cell imaging. NRLD achieves detection relying on the solvatochromic effect generated by excited-state charge transfer, and its emission wavelength shifts according to the local polarity changes of the microenvironment it locates in: the more compact and ordered the lipid packing and the lower the environmental polarity, the more blue-shifted the emission; the looser the lipid packing or the stronger the hydration and the higher the environmental polarity, the more red-shifted the emission. NRLD shows blue shift in the non-polar oil core of lipid droplets and red shift in high-polarity environments such as phosphate buffer .
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Cat. No.: HY-N18667
CAS No.: 84696-21-9
Centella asiatica extract is an orally active herbal extract. Centella asiatica extract scavenges free radicals, increases stratum corneum hydration, improves epidermal barrier function, and reduces skin redness and skin pH. Centella asiatica extract inhibits pro-inflammatory cytokines, suppresses p38 MAPK phosphorylation, reduces mast cell infiltration, and decreases the expression of TNF-α, IL-4, IL-5, IL-6, IL-17, CXCL9, iNOS and COX-2. Centella asiatica extract upregulates the expression of BDNF and downregulates the expression of VGLUT1, and exhibits neuroprotective effects under hypoxic conditions. Centella asiatica extract inhibits pro-inflammatory M1 macrophage polarization and prevents adipose tissue senescence. Centella asiatica extract can be used in studies related to hypoxia-induced neurological dysfunction, atopic dermatitis, and obesity-induced insulin resistance .
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