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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
152 Results for "
Injection
" in MedChemExpress (MCE) Product Catalog:
Products (152)
152 Results for "Injection" in MCE Product Catalog:
Cat. No.: HY-N16985
CAS No.: 29803-90-5
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Cat. No.: HY-P11614
Cat. No.: HY-P992126
CAS No.: 3059389-31-7
Synonyms: EYE-103; MK-3000
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Remigromig (EYE-103; MK-3000) is a humanized dual-target monoclonal antibody that targets LRP5 and FZD4. Remigromig activates the Wnt/β-catenin signaling pathway by mimicking the natural ligand Norrin, induces tight junction formation and restores blood-retinal barrier function. Administered via intravitreal injection, Remigromig reduces retinal vascular leakage, and demonstrates improvements in best-corrected visual acuity and reductions in retinal thickness in studies of diabetic macular edema. Remigromig can be used for research related to macular degeneration .
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Triamcinolone diacetate is a synthetic derivative of glucocorticoid. Triamcinolone diacetate has anti-inflammatory activity. Triamcinolone diacetate can be used in research on dermatomyositis, Bell's palsy and rheumatoid arthritis .
Cat. No.: HY-143700
CAS No.: 121315-93-3
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18:0 DAP is a cationic or ionizable lipid with no unsaturated bonds in its hydrocarbon chain. The mRNA encapsulation efficiency of 18:0 DAP is 0%. 18:0 DAP cannot form functional lipid nanoparticles suitable for mRNA delivery .
Cat. No.: HY-112142A
CAS No.: 422547-55-5
Synonyms: DVR-23
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(Rac)-AB-423 (DVR-23) is an anti-HBV candidate compound with promising anti-HBV activity. (Rac)-AB-423 showed no induction of CYP1A2, CYP3A4, or CYP2B6 enzyme activity at high concentrations. (Rac)-AB-423 exhibited desirable pharmacokinetic properties, enabling good systemic exposure and high oral bioavailability. (Rac)-AB-423 achieved more than 2 log viral load reduction in the hydrodynamic injection (HDI) HBV mouse model .
Cat. No.: HY-173116
CAS No.: 2051527-54-7
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DOTA-XYIMSR-01 is a molecular probe targeting CAIX that can be labeled with 177Lu for the inhibition and localization of malignant gliomas. The uptake of [177Lu] Lu-XYIMSR-01 in U87MG tumors is 6.19 % of the injected dose per gram (% ID/g), and the tumor-to-muscle uptake ratio is 20.14. In the orthotopic glioma model, combined injection with Temozolomide (HY-17364) can significantly improve the survival rate of mice and inhibit tumor growth. DOTA-XYIMSR-01 shows promise for research in the field of anti-cancer therapy .
Cat. No.: HY-P992142
CAS No.: 3050549-24-8
Synonyms: ANX-007
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Cat. No.: HY-W338446
CAS No.: 22191-97-5
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BF-170 is a selective tau fibril binding agent with an EC50 of 221 nM. It exhibits good blood-brain barrier permeability, and after intravenous injection in mice, the concentration in brain tissue reaches 9.1% ID/g within 2 minutes (with a brain clearance rate of 0.25% ID/g after 30 minutes). BF-170 can be used as a probe for tau protein pathology imaging in Alzheimer's disease (AD). It plays an important role in early-stage AD research and holds potential for imaging studies of tau-related neurodegenerative diseases .
Cat. No.: HY-139439
Purity: 98.83%
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SBI-581 is an orally active and potent selective serine-threonine kinase TAO3 inhibitor, with an IC50 of 42 nM. SBI-581 promotes TKS5α accumulation at RAB11-positive vesicles. SBI-581 inhibits invadopodia formation. SBI-581 shows reasonable pharmacokinetics in mice using IP injection. SBI-581 shows antitumor activity . SBI-581 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-D3068
CAS No.: 3077446-86-4
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LDs-BCA is a BF2-chelated AIE fluorescent probe with a positive solvatochromic effect, which can specifically target intracellular lipid droplets (Ex/Em = 565/620-730 nm). LDs-BCA monitors the dynamic changes in the morphology, size and quantity of intracellular lipid droplets under oleic acid induction and starvation stress. LDs-BCA, after intraperitoneal injection, accumulates in the gastric fat of living obese mice, allowing continuous monitoring via its fluorescent signal. LDs-BCA is applicable to studies related to intracellular lipid droplet polarity imaging and in vivo gastric fat visualization .
Cat. No.: HY-P1426
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Cat. No.: HY-L096
178 compounds
An inactive ingredient is any component of a drug product other than the active ingredient. Inactive ingredients are added during the manufacturing process of pharmaceutical products such as tablets, capsules, suppositories, and injections. In new drug development, once an inactive ingredient has appeared in an approved drug product for a particular route of administration, the inactive ingredient is not considered new and may require a less extensive review the next time it is included in a new drug product.
MCE offers a unique collection of 178 inactive ingredients, which only contain inactive ingredients of the final dosage forms of the drug. MCE Inactive Ingredient library is a powerful tool for aiding in the development of the drug and saving unnecessary time.
Cat. No.: HY-158976
Synonyms: Lactated ringer's solution (LRS)
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Sodium lactate ringer's solution (Lactated ringer's solution (LRS)) is an isotonic crystal intravenous injection and arthroscopic irrigation solution containing racemic sodium lactate and electrolytes such as sodium, potassium, calcium and chloride (130 mEq sodium/L, 274 mOsm/L), which can be used as a cell integrity protectant. Sodium lactate ringer's solution maintains the integrity of human meniscus cells, ensures that they retain normal cell morphology, membrane regularity, size and density, and does not alter the mRNA expression levels of α1 (I) procollagen, α1 (II) procollagen, aggrecan or HSP70. Sodium lactate ringer's solution can be applied to studies related to extracellular fluid deficiency and meniscus tears .
Cat. No.: HY-P11287
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Cat. No.: HY-P1426A
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Cat. No.: HY-P990120
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Cat. No.: HY-182098
DSPE-PEG1000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG1000-GALA can be used for drug delivery .
Cat. No.: HY-182098A
DSPE-PEG2000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG2000-GALA can be used for drug delivery .
Cat. No.: HY-182098B
DSPE-PEG3400-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG3400-GALA can be used for drug delivery .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
