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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
163 Results for "
DOTA
" in MedChemExpress (MCE) Product Catalog:
Products (163)
163 Results for "DOTA" in MCE Product Catalog:
Cat. No.: HY-186088
CAS No.: 3078821-76-5
Target:
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DOTA-tris (t-Bu) ester-PEG3-C2-amine (Compound 9) is a conjugate of DOTA-based chelator and linker, bearing tris (t-Bu) ester and PEG3-C2-amine functional groups. DOTA-tris (t-Bu) ester-PEG3-C2-amine can be conjugated to payloads via bioorthogonal click chemistry for targeted delivery .
Cat. No.: HY-167789
CAS No.: 2389064-47-3
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DOTA(tBu3)-PEG4-TFP is a chelating agent and linker conjugate that can be used in the synthesis of radiopharmaceuticals .
Cat. No.: HY-KD1115
The DOTA rapid labelling kit enables DOTA labelling of proteins. Based on NHS ester chemistry, NHS ester-activated fluorescent dyes react with primary amines on the antibody/protein to form stable amide bonds at pH 7–9, thereby achieving conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2–8 DOTA molecules. The entire procedure can be completed within 2 hours.
Cat. No.: HY-156870
CAS No.: 1392478-00-0
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DOTAGA dihydrochloride is the dihydrochloride salt of DOTAGA, a DOTA-derived macrocyclic chelator. DOTAGA dihydrochloride serves as a synthetic precursor to DOTAGA-anhydride (HY-W087187), which is further used to construct bifunctional DOTA-type chelators suitable for bioconjugation and metal labeling. DOTAGA dihydrochloride is applicable in synthetic research on chelators for molecular imaging and radiometal labeling .
Cat. No.: HY-W460274
CAS No.: 1402393-59-2
Cat. No.: HY-159181
CAS No.: 2194580-71-5
Cat. No.: HY-W586475
Research Areas:
Fluorescein-triazole-PEG5-DOTA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
Cat. No.: HY-W250929
CAS No.: 1613382-10-7
Cat. No.: HY-156038B
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(S)-p-SCN-Bn-DOTA TFA is a bifunctional chelator (BFC), a macrocyclic DOTA (HY-W053583) derivative for tumor pretargeting. (S)-p-SCN-Bn-DOTA TFA can be used for the conjugation of peptides and radionuclides, such as as a linker for In-111 labeled radioimmunoconjugates (RICs) for single photon emission tomography (SPECT) and in vitro biodistribution studies .
Cat. No.: HY-168343
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Ga-DOTA-Olmutinib is a potential PET tracer designed to detect EGFR-positive cancers .
Cat. No.: HY-48876
CAS No.: 181065-46-3
Cat. No.: HY-W782075
CAS No.: 116052-88-1
Cat. No.: HY-W749603
CAS No.: 479081-06-6
Cat. No.: HY-W717760
CAS No.: 446061-19-4
Cat. No.: HY-180447
CAS No.: 2756465-66-2
Research Areas:
Tz-Ph-PEG4-NH-DOTA (Compound 10) is a 1,2,4,5-tetrazine (Tz) derivative. Tz-Ph-PEG4-NH-DOTA can be used in PET imaging and tumor research .
Cat. No.: HY-164599
CAS No.: 2451069-30-8
Research Areas:
TA-DOTA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
Cat. No.: HY-100138R
CAS No.: 173308-19-5
Research Areas:
2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (Standard) is the analytical standard of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (HY-100138). This product is intended for research and analytical applications. 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) is a metal chelator precursor containing a DOTA macrocyclic structure. DOTA can form highly stable complexes with metal ions (such as 68Ga, 177Lu) through four nitrogen atoms and four carboxylic acid groups to mediate targeted delivery of radionuclides. The tert-butyl ester group (tBu ester) of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) also protects the carboxylic acid group during synthesis, and forms a free carboxyl group after deprotection reaction for coupling with targeting molecules (such as antibodies, peptides). 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) may be combined with tumor pre-targeting systems through bioorthogonal reactions (such as reverse electron demand Diels-Alder reaction) to study radioactive imaging or therapy of tumor tissues, and is mainly used in tumor pre-targeting research in the field of nuclear medicine .
Cat. No.: HY-180447A
Research Areas:
Tz-Ph-PEG4-NH-DOTA (Compound 10) tetraTFA is a 1,2,4,5-tetrazine (Tz) derivative. Tz-Ph-PEG4-NH-DOTA tetraTFA can be used in PET imaging and tumor research .
Cat. No.: HY-164594
Research Areas:
TA-DOTA-GA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
