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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
163 Results for "
DOTA
" in MedChemExpress (MCE) Product Catalog:
Products (163)
163 Results for "DOTA" in MCE Product Catalog:
Research Areas:
2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) is a metal chelator precursor containing a DOTA macrocyclic structure. DOTA can form highly stable complexes with metal ions (such as 68Ga, 177Lu) through four nitrogen atoms and four carboxylic acid groups to mediate targeted delivery of radionuclides. The tert-butyl ester group (tBu ester) of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) also protects the carboxylic acid group during synthesis, and forms a free carboxyl group after deprotection reaction for coupling with targeting molecules (such as antibodies, peptides). 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) may be combined with tumor pre-targeting systems through bioorthogonal reactions (such as reverse electron demand Diels-Alder reaction) to study radioactive imaging or therapy of tumor tissues, and is mainly used in tumor pre-targeting research in the field of nuclear medicine .
Cat. No.: HY-W999782
CAS No.: 911197-00-7
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Propargyl-DOTA-tris(tBu)ester is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging .
Cat. No.: HY-158077
CAS No.: 148408-89-3
Synonyms: (R)-tetraMe-DOTA
Cat. No.: HY-173383
Synonyms: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt
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DOPE-DOTA sodium is a chelated lipid that serves as a key contrast agent in magnetic resonance imaging (MRI). DOPE-DOTA sodium can be used for cancer, blood-brain barrier disruption, abnormalities such as aneurysms or plaque buildup, inflammation in arthritis, and liver function and lesions study
Cat. No.: HY-173384
Synonyms: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt
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DSPE-DOTA sodium (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt) is a chelating lipid used as a key contrast agent in magnetic resonance imaging (MRI). DSPE-DOTA sodium can be used for imaging detection of tumors, neurological and inflammatory diseases .
Cat. No.: HY-P11591
CAS No.: 3110124-60-9
Synonyms: PSMA-DOTA-PEI2
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Cat. No.: HY-P10131
CAS No.: 2803421-14-7
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Cat. No.: HY-P10951
CAS No.: 2647371-60-4
Synonyms: (R)-PSMA I&T; (R)-PNT-2002
Cat. No.: HY-P11969
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10YX is a cyclic peptide probe targeting glypican-3 (GPC3) (Kd = 300.4 nM for human GPC3). It achieves tumor targeting by binding to GPC3 sitemap2 and serves as a PET imaging probe for tumor visualization and intrahepatic lesion localization. 10YX is useful for research on hepatocellular carcinoma .
Cat. No.: HY-P11769
CAS No.: 1186600-65-6
Synonyms: RM2
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Cat. No.: HY-P11846
Target:
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Synonyms: DO3A tert-butyl; DO3A-t-Bu-ester
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DOTA tert-Butyl ester is a cyclic tosamide benzyl derivative.
Cat. No.: HY-P12129
Research Areas:
Zaregreptide dizuxetan is a SSTR-targeting peptide-DOTA variant conjugate. Zaregreptide dizuxetan can be conjugated with 177Lutetium for the study of SSTR-positive neuroendocrine tumors .
Cat. No.: HY-P2218
CAS No.: 1821136-83-7
Synonyms: Pentixather
Research Areas:
Anditixafortide (Pentixather) is an endoradiotherapeutic vector. Anditixafortide is a CXCR4-targeting peptide derivative . Anditixafortide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
Cat. No.: HY-W726767
CAS No.: 112193-75-6
Cat. No.: HY-W250844A
CAS No.: 217973-03-0
Cat. No.: HY-W046355
CAS No.: 198544-42-2
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Cat. No.: HY-131673A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
