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  4. DO3A trisodium

DO3A (trisodium)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO3A (trisodium) can be used for conjugation of peptides and radionuclides.

For research use only. We do not sell to patients.

DO3A trisodium

DO3A trisodium Chemical Structure

CAS No. : 217973-03-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
1 g In-stock
5 g In-stock
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50 g   Get quote  

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Description

DO3A (trisodium)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO3A (trisodium) can be used for conjugation of peptides and radionuclides.

Molecular Weight

412.32

Formula

C14H23N4Na3O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CN1CCNCCN(CCN(CC1)CC(O[Na])=O)CC(O[Na])=O)O[Na]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (242.53 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4253 mL 12.1265 mL 24.2530 mL
5 mM 0.4851 mL 2.4253 mL 4.8506 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4253 mL 12.1265 mL 24.2530 mL 60.6325 mL
5 mM 0.4851 mL 2.4253 mL 4.8506 mL 12.1265 mL
10 mM 0.2425 mL 1.2127 mL 2.4253 mL 6.0633 mL
15 mM 0.1617 mL 0.8084 mL 1.6169 mL 4.0422 mL
20 mM 0.1213 mL 0.6063 mL 1.2127 mL 3.0316 mL
25 mM 0.0970 mL 0.4851 mL 0.9701 mL 2.4253 mL
30 mM 0.0808 mL 0.4042 mL 0.8084 mL 2.0211 mL
40 mM 0.0606 mL 0.3032 mL 0.6063 mL 1.5158 mL
50 mM 0.0485 mL 0.2425 mL 0.4851 mL 1.2127 mL
60 mM 0.0404 mL 0.2021 mL 0.4042 mL 1.0105 mL
80 mM 0.0303 mL 0.1516 mL 0.3032 mL 0.7579 mL
100 mM 0.0243 mL 0.1213 mL 0.2425 mL 0.6063 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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DO3A trisodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DO3A trisodium217973-03-0Biochemical Assay ReagentsInhibitorinhibitorinhibit

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