1680 Results for "

Precursor

" in MedChemExpress (MCE) Product Catalog:
Products (1680)

1680 Results for "Precursor" in MCE Product Catalog:

Cat. No.: HY-110189S1
CAS No.: 1485492-21-4
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate-d4 sodium
Pregnenolone monosulfate-d4 sodium is the deuterium labeled Pregnenolone monosulfate sodium (HY-110189) . Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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Cat. No.: HY-130245
Purity:  98.33%
Target:  

HyT PCSK9

Research Areas:  

Metabolic Disease

PCSK9 degrader 1 is a HyT-like PCSK9 degrader with a Ki of 107 nM. PCSK9 degrader 1 binds to the allosteric pocket between the catalytic domain and C-terminal domain of PCSK9. While maintaining key interactions with this protein, it extends the proteasome-recruiting moiety, thereby driving degradation via the proteasomal pathway. PCSK9 degrader 1 induces the degradation of both the precursor and mature forms of PCSK9, with DC50 values of 4.8 μM and 3.4 μM respectively, and does not significantly affect cell viability or the expression of housekeeping proteins. PCSK9 degrader 1 can be used in the research of coronary heart disease .
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Cat. No.: HY-138615S3
Synonyms: dTTP-15N2,d15 dilithium
Deoxythymidine-5'-triphosphate- 15N2,d15 dilithium (dTTP- 15N2,d15 dilithium) is the deuterated, 15N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is a deoxyribonucleoside triphosphate and a thymidine analog, which serves as a direct precursor for DNA synthesis. Deoxythymidine-5'-triphosphate can be used for DNA amplification in the DNA polymerase chain reaction (PCR). Deoxythymidine-5'-triphosphate is also applicable to research related to diseases such as leukemia .
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Cat. No.: HY-150177
CAS No.: 3672-15-9
Mannose 6 phosphate is an essential precursor for mannosyl glycoconjugates, including lipid-linked oligosaccharides (LLO; glucose3mannose9GlcNAc2-P-P-dolichol) used for protein N-glycosylation. Mannose 6 phosphate causes specific LLO cleavage. Mannose 6 phosphate causes specific degradation of G3M9Gn2-P-P-Dol. Complexes containing Mannose 6 phosphate can remodel the dermal collagen network, improve skin biomechanical properties, and reverse visible signs of aging. Mannose 6 phosphate can be used in research related to skin aging .
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Cat. No.: HY-78726S2
Synonyms: Amprenavir phosphate-13C6; GW 433908-13C6
Fosamprenavir- 13C6 is the 13C-labeled Fosamprenavir (HY-78726). Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection .
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Cat. No.: HY-B1716S2
CAS No.: 1246818-91-6
Synonyms: L-5-HTP-d4; Oxitriptan-d4
L-5-Hydroxytryptophan-d4 (L-5-HTP-d4; Oxitriptan-d4) is a deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
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Cat. No.: HY-N0902
CAS No.: 3606-45-9
Synonyms: 13,14-Dihydrosanguinarine
Dihydrosanguinarine (13,14-Dihydrosanguinarine) is an alkaloid with antibacterial and anti-inflammatory activities, and also an important precursor of Sanguinarine (HY-N0052). Dihydrosanguinarine targets and regulates the TNF/IL-17/PI3K signaling pathway, downregulates the levels of pro-inflammatory factors such as IL-17A, TNF-α and IL-6, upregulates the expression of TGF-β, inhibits myeloperoxidase activity, and regulates the transcription of multiple inflammation-related genes. Dihydrosanguinarine exhibits antibacterial activity against a variety of oral microorganisms. Dihydrosanguinarine can be used in research related to liver inflammation and oral flora dysbiosis .
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Cat. No.: HY-P10489
CAS No.: 374675-19-1
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

Kisspeptin-14 human is a peptide hormone encoded by the KiSS-1 gene. Kisspeptin-14 human, along with several other similar peptide hormones, is produced from a common precursor protein by cleavage by different proteases. Kisspeptin-14 human is an endogenous ligand of KISS1R. Kisspeptin-14 human has the same receptor binding efficiency and potency as full-length kisspeptin. Kisspeptin-14 human binds to its receptor GPR54 and is able to activate this G protein-coupled receptor and activate multiple intracellular signaling pathways. Kisspeptin-14 human can be used to study reproductive development and tumor metastasis .
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Cat. No.: HY-W013222
CAS No.: 55066-53-0
Research Areas:  

Others

(R,Z)-Ethyl 12-hydroxyoctadec-9-enoate is a naturally occurring organic compound belonging to the class of fatty acid esters. It is derived from oleic acid, a common unsaturated fatty acid found in various animal and plant sources. (R,Z)-Ethyl 12-hydroxyoctadec-9-enoate contains an ethyl group and a hydroxyl group at specific positions in the fatty acid chain. It has various applications in industry and biomedicine, especially as a precursor for the synthesis of other bioactive compounds. (R,Z)-Ethyl 12-hydroxyoctadec-9-enoate is also used in the formulation of certain types of cosmetic and personal care products, such as skin creams and lotions.
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Cat. No.: HY-W067445
CAS No.: 122-85-0
Synonyms: 4-Acetamidobenzaldehyde
N-(4-Formylphenyl) acetamide (4-Acetamidobenzaldehyde) is an organic ligand bearing aldehyde and acetamide functional groups. N-(4-Formylphenyl) acetamide can be used to functionalize Fe3O4@SiO2 nanoparticles for selective fluorescence quenching detection of Hg 2+. N-(4-Formylphenyl) acetamide serves as a precursor for the synthesis of benzimidazole, benzothiazole and Schiff base derivatives, which exhibit antioxidant, AChE/BChE inhibitory and DNA-binding activities. N-(4-Formylphenyl) acetamide can be applied in studies related to Alzheimer's disease .
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Cat. No.: HY-Y0543R
CAS No.: 620-02-0
5-Methylfurfural (Standard) is the analytical standard of 5-Methylfurfural. This product is intended for research and analytical applications. 5-Methylfurfural is a chemical that can be utilized as food additive, intermediate in the production of agrochemicals, and precursor of certain anti-cancer natural products. 5-Methylfurfural is formed during the photoexposition of ranitidine hydrochloride. 5-Methylfurfural is an organic compound. 5-Methylfurfural has a strong tendency to be further hydrogenated to 2,5-dimethylfuran (DMF). 5-Methylfurfural can predominantly evoke skin inflammation and barrier disintegration. 5-Methylfurfural degrades native DNA through the formation of single-strand breaks .
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Cat. No.: HY-P70660
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-P81176
Synonyms: Integrin alpha-X; integrin alpha-X Precursor; ITGAX; SLEB6; CD11C (p150) alpha polypeptide; complement receptor 4; integrin aX; CD11 antigen-like family member C; leukocyte adhesion receptor p150,95; leukocyte adhesion glycoprotein p150,95 alpha chain; ITAX_HUMAN.

Host:  

Rabbit

Application:  

FC

Reactivity:  

Human, Rat

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Cat. No.: HY-P705391
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:  
Cynomolgus
Source:  
E. coli
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Cat. No.: HY-124370
CAS No.: 13058-52-1
Purity:  99.2%
Synonyms: 9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease Cancer

9 (Z),11 (E)-Conjugated linoleic acid methyl ester (9Z,11E-CLA; Methyl 9 (Z),11 (E)-octadecadienoate; (9Z,11E)-SFE 19:2) is an isomer of Linoleic acid (HY-N0729), and is a conjugated linoleic acid mainly found in meat and dairy products. Conjugated linoleic acid is a bioactive fatty acid that improves body composition, enhances immune system function, and exhibits anti-cancer and anti-atherosclerotic effects .
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Cat. No.: HY-W1057999
CAS No.: 104149-14-6
Research Areas:  

Cancer

Bromofosfamide is a prodrug-type alkylating agent and also an analog of Ifosfamide (HY-17419). Bromofosfamide exhibits potent in vivo anti-tumor activity against lymphoid leukemia and can be used for the research of lymphoid leukemia .
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Cat. No.: HY-P704889
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704891
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P704892
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P704894
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:  
Human
Source:  
E. coli
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