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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
169 Results for "
PC-3
" in MedChemExpress (MCE) Product Catalog:
Products (169)
169 Results for "PC-3" in MCE Product Catalog:
Cat. No.: HY-RS19122
Target:
Research Areas:
Cbx8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cbx8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-175826
Research Areas:
USP30-IN-20 is an orally active USP30 inhibitor (Kd = 1.61 μM, IC50 = 12.8 μM). USP30-IN-20 induces ferroptosis by promoting ubiquitination-mediated degradation of GPX4. USP30-IN-20 inhibits the proliferation, migration, invasion, and stemness of prostate cancer cells. USP30-IN-20 induces G0/G1 cell cycle arrest and ROS levels in prostate cancer cells. USP30-IN-20 exhibits significant anti-tumor efficacy in PC3 cell subcutaneous xenografts in mice. USP30-IN-20 can be used for the study of advanced prostate cancer .
Cat. No.: HY-403733C
CAS No.: 2020353-42-6
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JJ-450 is a non-competitive antagonist androgen receptor (AR) that inhibits the transcriptional activity of wild-type AR and mutant AR F876L. JJ-450 has an IC50 of approximately 1-10 μM in inhibiting AR transcriptional activity in PC3 cells. It is selective for AR binding and does not compete with androgens for binding to the ligand binding domain (LBD) of AR. JJ-450 inhibits the transcriptional activity of AR and its splice variants (such as AR F876L) by inhibiting AR nuclear translocation and promoting the degradation of unliganded AR in the nucleus. JJ-450 can be used in castration-resistant prostate cancer (CRPC) studies that are resistant to Enzalutamide (MDV3100) (HY-70003) .
Cat. No.: HY-P77462
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PCSK1; SPC3; Prev. NEC1; Proprotein Convertase 1/3; Neuroendocrine Convertase 1; Prohormone Convertase 3; Prohormone Convertase 1; Proprotein Convertase 1; PC1; BMIQ12; PC1/3; NEC 1; Proprotein Convertase Subtilisin/Kexin Type 1; PC3
Species:
Human
Source:
HEK293
Cat. No.: HY-RS02015
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Research Areas:
CBX8 Human Pre-designed siRNA Set A contains three designed siRNAs for CBX8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00229
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Research Areas:
ACTR1B Human Pre-designed siRNA Set A contains three designed siRNAs for ACTR1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01663
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Research Areas:
BTG2 Human Pre-designed siRNA Set A contains three designed siRNAs for BTG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20698
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Research Areas:
Btg2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Btg2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25020
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Research Areas:
Pcsk1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pcsk1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P1793
CAS No.: 83471-50-5
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Cat. No.: HY-P1793A
Research Areas:
Cat. No.: HY-RS27209
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Research Areas:
Btg2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Btg2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-157880
Synonyms: Azido-PC
Target:
Research Areas:
N3-PC (Azido-PC) is a photoactivatable phosphatidylcholine that can be used in the synthesis of cell membrane structures. N3-PC (Azido-PC) is a click chemistry reagent containing an azide group .
Cat. No.: HY-RS10170
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Research Areas:
PCSK1 Human Pre-designed siRNA Set A contains three designed siRNAs for PCSK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18538
Target:
Research Areas:
Pcsk1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pcsk1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N7535
CAS No.: 96801-92-2
Target:
Cat. No.: HY-RS07458
Target:
Research Areas:
KRT6A Human Pre-designed siRNA Set A contains three designed siRNAs for KRT6A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-175555
Target:
Research Areas:
Tubulin-IN-54 is a tubulin inhibitor. Tubulin-IN-54 exhibits anti-proliferative activity against various cancer cells. Tubulin-IN-54 inhibits tubulin polymerization, disrupts microtubule networks, induces G2/M cell cycle arrest, and promotes cancer cell apoptosis. Tubulin-IN-54 demonstrates significant anti-tumor efficacy in mice bearing PC-3/TxR xenografts. Tubulin-IN-54 can be used for the study of taxane-resistant cancers (prostate cancer, melanoma) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
