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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1680 Results for "
precursor
" in MedChemExpress (MCE) Product Catalog:
Products (1680)
1680 Results for "precursor" in MCE Product Catalog:
Cat. No.: HY-N9551
CAS No.: 14917-41-0
Category:
Flavonoids Chalcones Metabolic Disease Phenols Polyphenols Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Plants Umbelliferae Disease Research Fields
Target:
Cat. No.: HY-P11590
Cat. No.: HY-P990301
Target:
Research Areas:
Cat. No.: HY-W002304R
CAS No.: 4042-36-8
Target:
Cat. No.: HY-W013159S
Synonyms: 5′-dGMP-13C10,15N5 disodium
Cat. No.: HY-W015924R
CAS No.: 594-61-6
Cat. No.: HY-W027592
CAS No.: 61-82-5
Cat. No.: HY-W753956
CAS No.: 3044090-39-0
Cat. No.: HY-W778990
CAS No.: 478510-94-0
Cat. No.: HY-P703601
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBA3; NEDD8-Activating Enzyme E1 Subunit 2; Prev. UBE1C; NEDD8-Activating Enzyme E1C; NEDD8-Activating Enzyme E1 Catalytic Subunit; UBA3, Ubiquitin-Activating Enzyme E1 Homolog; HUba3; Ubiquitin-Like Modifier Activating Enzyme 3; NAE2; Ubiquitin-Like Modifier-Activating Enzyme 3; Ubiquitin-Activating Enzyme E1C (Homologous To Yeast UBA3); Ubiquitin-Activating Enzyme E1C; Ubiquitin-Activating Enzyme E1C (UBA3 Homolog, Yeast); Nedd8-Activating Enzyme HUba3; Ubiquitin Like Modifier Activating Enzyme 3; Ubiquitin-Activating Enzyme 3; NAE1; Proto-Oncogene Protein 1; Prev. APPBP1; NEDD8-Activating Enzyme E1 Subunit; APP-BP1; Alternative Protein NAE1; Ula-1; Protooncogene Protein 1; Amyloid Beta precursor Protein-Binding Protein 1, 59 KDa; A-116A10.1; Amyloid Beta precursor Protein Binding Protein 1, 59kDa; NEDFIH; NEDD8-Activating Enzyme E1 Regulatory Subunit; HPP1; Amyloid Protein-Binding Protein 1; NEDD8 Activating Enzyme E1 Subunit 1; Amyloid Beta precursor Protein-Binding Protein 1, 59kD
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-N17580
CAS No.: 150415-40-0
Category:
Target:
Cat. No.: HY-P81215
Synonyms: Bone Marrow Serine Protease; ELA 2; ELA2; ELANE; Elastase 2; Elastase-2; Elastase 2 neutrophil; Elastase neutrophil expressed; Elastase-2; ELNE_HUMAN; GE antibody Granulocyte derived elastase; HLE; HNE; Human leukocyte elastase; Leukocyte elastase; Leukocyte Elastase precursor; Medullasin; NE; Neutrophil elastase; Neutrophill elastase; PMN E; PMN Elastase; Polymorphonuclear elastase; SCN1; Serine protease; SERP1.
Cat. No.: HY-P86747
Synonyms: beta-Amyloid(1-42); A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid beta A4 Protein precursor; Amyloid beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid; beta APP; Cerebral Vascular Amyloid Peptide; CTFgamma; CVAP; PN II; PN2; PreA4; Protease nexin II; A beta; Amyloid 1-42.Aβ
Cat. No.: HY-183283
Target:
Carbonic Anhydrase Apoptosis NOD-like Receptor (NLR) Interleukin Related Reactive Oxygen Species (ROS)
Research Areas:
CAII-IN-15 is a potent carbonic anhydrase II (CA II) inhibitor with a hCA II IC50 of 10 nM. CAII-IN-15 elevates cGMP levels, releases nitric oxide, reduces oxidative stress, and exhibits neuroprotective activity in vitro. CAII-IN-15 inhibits NLRP3 inflammasome activation, reduces neuronal apoptosis. CAII-IN-15 reduces Intraocular pressure (IOP) in rabbits. CAII-IN-15 can be used for the research of glaucoma .
Cat. No.: HY-P5007
CAS No.: 78362-34-2
Research Areas:
Cat. No.: HY-P5007A
Target:
Research Areas:
Copeptin (human) acetate is a peptide biochemical reagent corresponding to the 39 amino acid sequence at the C-terminus of human pre-provasopressin, which serves as a stable surrogate biomarker reflecting the secretion of arginine vasopressin (AVP). Copeptin (human) acetate can be used in studies related to AVP secretion, fluid and osmotic homeostasis, stress responses, and cardiovascular biomarkers .
Research Areas:
2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) is a metal chelator precursor containing a DOTA macrocyclic structure. DOTA can form highly stable complexes with metal ions (such as 68Ga, 177Lu) through four nitrogen atoms and four carboxylic acid groups to mediate targeted delivery of radionuclides. The tert-butyl ester group (tBu ester) of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) also protects the carboxylic acid group during synthesis, and forms a free carboxyl group after deprotection reaction for coupling with targeting molecules (such as antibodies, peptides). 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) may be combined with tumor pre-targeting systems through bioorthogonal reactions (such as reverse electron demand Diels-Alder reaction) to study radioactive imaging or therapy of tumor tissues, and is mainly used in tumor pre-targeting research in the field of nuclear medicine .
Cat. No.: HY-151744
CAS No.: 1993119-45-1
Target:
Research Areas:
N3-TFBA-O2Oc is a click chemistry reagent containing an azide group and an aryl group. Aryl azides are well-known precursors of nitrenes and have been introduced by Fleet et al. as versatile photoaffinity labeling agents to probe biological receptors. This type of compounds has been used as photo-cross linker (λmax=258 nm) in estrogen receptor studies and for direct surface coating of carbon and organic based polymers . N3-TFBA-O2Oc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-165624B
CAS No.: 136296-43-0
Target:
Research Areas:
(R)-LY-41, R-enantiomer of LY-41 (HY-165624), is 2-Sminotetralin (HY-W022362) derivative and 8-OH-DPAT (HY-112061) analogue. (R)-LY-41 is a potent and selective 5-HT1A receptor agonist. (R)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (R)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (R)-LY-41 can induce the 5-HT behavioral syndrome but is weaker than (S)-LY-41 (HY-165624A). (R)-LY-41 can be used for the research of neurological disease, such as depression and anxiety .
Cat. No.: HY-D2984
CAS No.: 1308789-62-9
Synonyms: SNAP-PEG-NH2
Target:
Research Areas:
BG-PEG-NH2 (SNAP-PEG-NH2) is an amino-terminal fluorescent probe building block and a precursor for site-specific labeling of SNAP-tag fusion proteins. BG-PEG-NH2 undergoes one-step coupling with activated carboxyl esters to form customized SNAP-tag substrates, which covalently bind to SNAP tags via a thioether bond formed at the Cys145 site. After coupling with a caged carboxyfluorescein, BG-PEG-NH2 forms a probe with Ex/Em = 500/524 nm following ultraviolet uncaging. Coupling of BG-PEG-NH2 with SeTau-647-NHS enables visualization of GPCR signal transduction. BG-PEG-NH2 is suitable for coupling reactions in aqueous phases or buffers, conjugation of labels, and labeling of intracellular or cell-surface proteins .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
