Search Result

Results for "

β Glucan

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (17) AP-1 (1) Apoptosis (1) Bacterial (7) Biochemical Assay Reagents (6) Cholinesterase (ChE) (1) Endogenous Metabolite (14) Environmental Pollutants (1) Fungal (36) GLUT (1) Glycosidase (5) Glycosyltransferase (1) HIV (1) IKK (1) Interleukin Related (1) Isotope-Labeled Compounds (2) JNK (1) NO Synthase (1) p38 MAPK (1) Phospholipase (1) PIN1 (1) PPAR (1) Reactive Oxygen Species (ROS) (2) Reference Standards (5) Sirtuin (1) TGF-beta/Smad (1) TGF-β Receptor (1) Toll-like Receptor (TLR) (4)
By Research Areas:	Cancer (13) Cardiovascular Disease (1) Infection (38) Inflammation/Immunology (5) Metabolic Disease (15) Neurological Disease (1)

By Targets:

Antibiotic (17)

AP-1 (1)

Apoptosis (1)

Bacterial (7)

Biochemical Assay Reagents (6)

Cholinesterase (ChE) (1)

Endogenous Metabolite (14)

Environmental Pollutants (1)

Fungal (36)

GLUT (1)

Glycosidase (5)

Glycosyltransferase (1)

HIV (1)

IKK (1)

Interleukin Related (1)

Isotope-Labeled Compounds (2)

JNK (1)

NO Synthase (1)

p38 MAPK (1)

Phospholipase (1)

PIN1 (1)

PPAR (1)

Reactive Oxygen Species (ROS) (2)

Reference Standards (5)

Sirtuin (1)

TGF-beta/Smad (1)

TGF-β Receptor (1)

Toll-like Receptor (TLR) (4)

By Research Areas:

Cancer (13)

Cardiovascular Disease (1)

Infection (38)

Inflammation/Immunology (5)

Metabolic Disease (15)

Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W145521

β-1,3-Glucan 1 Publications Verification β Glucan	Biochemical Assay Reagents IKK NO Synthase Bacterial	Infection Inflammation/Immunology Cancer
β-1,3-Glucan (β Glucan) is an orally active polysaccharide composed of glucose polymers. β-1,3-Glucan increase the activity of IKKβ kinase, enhances the production of nitric oxide. β-1,3-Glucan improves resistance to *Vibrio harveyi* infection. β-1,3-Glucan enhances immune response, promotes blood pressure recovery, reduces lung, kidney and liver damage, inhibits the growth of syngeneic tumors .

HY-17006

Caspofungin diacetate 5+ Cited Publications MK-0991 diacetate; L-743872 diacetate	Fungal Antibiotic Bacterial	Infection Cancer
Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-119109

Laminaran 1 Publications Verification	Environmental Pollutants Endogenous Metabolite	Cancer
Laminaran is an *β-1-3-glucan* and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities . Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .

HY-E70013

Lichenase, Microorganism endo-1,3:1,4-β-D-Glucanase	Endogenous Metabolite	Metabolic Disease
Lichenase, Microorganism (endo-1,3:1,4-β-D-Glucanase) is a specific, endo-(1-3),(1-4)-β-D-glucan 4-glucanohydrolase. Lichenase, Microorganism solubilizes β-glucans from cereal grains and gives gluco-oligosaccharides (GOS). Lichenase, Microorganism can be used in the degradation of polysaccharides in the cell walls .

HY-139413

β-D-Glucan 1 Publications Verification	Toll-like Receptor (TLR)	Cancer
β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery . β-d-glucan is an enteric delivery vehicle for probiotics .

HY-16321

Micafungin sodium Maximum Cited Publications 20 Publications Verification FK 463 sodium	Fungal Antibiotic	Infection Cancer
Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.

HY-17579

Micafungin Maximum Cited Publications 20 Publications Verification FK463	Fungal Antibiotic	Infection Cancer
Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.

HY-17006A

Caspofungin 5+ Cited Publications MK-0991; L-743872	Antibiotic Fungal Bacterial	Infection Cancer
Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-107126

Ibrexafungerp MK 3118; SCY-078	Fungal	Infection
Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections .

HY-107126A

Ibrexafungerp citrate MK 3118 citrate; SCY-078 citrate	Fungal	Infection
Ibrexafungerp citrate (MK 3118 citrate) is an orally active *β-1,3-glucan* synthesis** inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections .

HY-P3004

Endo-1,3-β-glucanase Lyticase	Endogenous Metabolite Fungal	Infection
Endo-1,3-β-glucanase (Lyticase) is an endoenzyme that can specifically cleave β-1,3-glycosidic bonds. Endo-1,3-β-glucanase recognizes and binds to β-1,3-glucan chains, catalyzing the cleavage of glycosidic bonds and hydrolyzing polysaccharides into oligosaccharides. Endo-1,3-β-glucanase eliminates vaginal Candida. Endo-1,3-β-glucanase can be used in the study of recurrent Candida vaginitis .

HY-W050145

Levoglucosan 1,6-Anhydro-β-D-glucopyranose; 1,6-Anhydro-β-D-glucose	Endogenous Metabolite	Metabolic Disease
Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-147295

Odetiglucan BTH 1677; Imprime PGG	Toll-like Receptor (TLR)	Inflammation/Immunology Cancer
Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response .

HY-165126

Schizophyllan SPG	Endogenous Metabolite Sirtuin JNK p38 MAPK PPAR AP-1	Infection Metabolic Disease Inflammation/Immunology Cancer
Schizophyllan (SPG) is an orally active extracellular β-glucan produced by the fungus Schizophyllum commune. Schizophyllan improves mitochondrial function and protects against metabolic liver injury by activating the SIRT3 pathway. Schizophyllan inhibits osteoclastogenesis and promotes osteoblast differentiation by suppressing the phosphorylation of JNK/p38, as well as downregulating PGC1β/PPARγ, c-Fos and NFATc1. Recognized via Dectin-1, schizophyllan enables precise delivery of oligonucleotide drugs and antigens to antigen-presenting cells, thus holding great potential in the treatment of inflammatory diseases and vaccine development .

HY-W050145S

Levoglucosan-d7 1,6-Anhydro-β-D-glucopyranose-d₇; 1,6-Anhydro-β-D-glucose-d₇	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Levoglucosan-d₇ is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-N8537

Enfumafungin	Fungal	Infection
Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis .

HY-N15135

Arabinoxylan (Medium viscosity)	Interleukin Related Toll-like Receptor (TLR) Fungal	Metabolic Disease
Arabinoxylan Medium viscosity is an orally active Dectin-1 splice variant modulator, glucose absorption inhibitor, and chyme viscosity enhancer. Arabinoxylan Medium viscosity inhibits particulate β-glucan-induced Dectin-1A activation and mildly suppresses Dectin-1B activation. In human dendritic cells stimulated with particulate β-glucan, Arabinoxylan Medium viscosity reduces the production of IL-10 and TNF-α, and increases the production of IL-4 and IL-23. Arabinoxylan Medium viscosity also supports antifungal immune responses without activating TLR2, TLR4 or TLR5, and does not induce cytokine production when used to stimulate human dendritic cells alone. Arabinoxylan Medium viscosity increases small intestinal chyme viscosity, gets degraded in the large intestine to produce short-chain fatty acids, reduces glucose absorption and insulin response, and improves glucose homeostasis. Arabinoxylan Medium viscosity supports microbial fermentation and the growth of beneficial microbiota in the gastrointestinal tract, prevents bile acid reabsorption, and delays starch digestion. Arabinoxylan Medium viscosity can be used in research related to type 2 diabetes, impaired glucose tolerance, and metabolic syndrome .

HY-N6924

Zingibroside R1 1 Publications Verification	HIV PIN1 Fungal GLUT Reactive Oxygen Species (ROS)	Infection Neurological Disease Metabolic Disease Cancer
Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .

HY-134655

D75-4590 1 Publications Verification	Fungal	Infection Inflammation/Immunology
D75-4590, a pyridobenzimidazole derivative and a *β-1,6-glucan* synthesis inhibitor, possesses antifungal activity .

HY-163462

Poacic acid	Fungal	Infection
Poacic Acid is a plant-derived stilbenoid with an antifungal activity. Poacic Acid localizes to the yeast cell wall and disrupts the production and assembly of β-1,3-glucan in the fungal cell walls. Poacic Acid exhibits fungicidal activity to Saccharomyces cerevisiae and plasma membrane-compromised Candida albicans mutants .

HY-E70013A

Licheninase EC 3.2.1.73	Glycosidase	Others
Licheninase (EC 3.2.1.73) is a glycoside hydrolase is active on the β-glucan cell wall of cereals, fungi, and seaweed. Licheninase specifically hydrolyzes β(1→4) linkages in mixed linkage β(1→3)/β(1→4)-glucans. Licheninase improves cellulose degradation .

HY-125723

Echinocandin B SL 7810; A-30912 A	Endogenous Metabolite Fungal Antibiotic	Infection
Echinocandin B (SL 7810) is a lipopeptide antifungal antibiotic. Echinocandin B is produced by Aspergillus nidulans. Echinocandin B inhibits *β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B exhibits activity against a variety of Aspergillus species .

HY-17006S

Caspofungin-d4 diacetate MK-0991-d4 diacetate; L-743872-d4 diacetate	Fungal Bacterial Antibiotic	Infection
Caspofungin-d₄ (acetate) is the deuterium labeled Caspofungin diacetate . Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-N8279

β-1,3-1,4-Glucanase Endo-β-1,3-1,4-Glucanase	Glycosidase	Metabolic Disease
β-1,3-1,4-glucanase (Endo-β-1,3-1,4-glucanase) is a glycoside hydrolase family 16 enzyme (some members belong to subfamily 25). β-1,3-1,4-glucanase shows high substrate specificity toward mixed‑linked β‑glucans and cleaves β‑1,4 glycosidic bonds adjacent to β‑1,3 linkages in an endo‑type pattern. β-1,3-1,4-glucanase can be used in industrial enzyme applications and monogastric animal feed supplementation .

HY-P3906

Melittin free acid	Fungal Apoptosis Phospholipase Reactive Oxygen Species (ROS)	Infection
Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .

HY-P11003

PTD-N5-1	Toll-like Receptor (TLR)	Inflammation/Immunology
PTD-N5-1 (N5-1) is an IRF5 inhibitory peptide. PTD-N5-1 blocks β-glucan-induced IL-12 production in IFN-γ primed wild-type and Clec2d-difecient bone-marrow-derived dendritic cells (BMDCs). PTD-N5-1 regulates antifungal immunity through suppression of IRF5-mediated IL-12 production .

HY-145348

MK-5204	Fungal	Infection
MK-5204 is an orally active β-1,3-glucan synthesis inhibitor.

HY-P2763

beta-Glucanase	Glycosidase Fungal	Infection Cardiovascular Disease
beta-Glucanase belongs to glycosyl hydrolase family that hydrolyzes β-glucan polysaccharide, producing 3-O-cellotriosyl-d-glucose and 3-O-cellobiosyl-d-glucose. beta-Glucanase is capable of protecting plants against different fungal pathogens .

HY-16321R

Micafungin sodium (Standard) FK 463 sodium (Standard)	Reference Standards Fungal Antibiotic	Infection Cancer
Micafungin (sodium) (Standard) is the analytical standard of Micafungin (sodium). This product is intended for research and analytical applications. Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.

HY-W050145R

Levoglucosan (Standard) 1,6-Anhydro-β-D-glucopyranose (Standard); 1,6-Anhydro-β-D-glucose (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Levoglucosan (Standard) is the analytical standard of Levoglucosan. This product is intended for research and analytical applications. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-17006R

Caspofungin diacetate (Standard) MK-0991 diacetate (Standard); L-743872 diacetate (Standard)	Reference Standards Fungal Antibiotic Bacterial	Infection Cancer
Caspofungin (diacetate) (Standard) is the analytical standard of Caspofungin (diacetate). This product is intended for research and analytical applications. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-107126B

Ibrexafungerp phosphate MK 3118 phosphate; SCY-078 phosphate	Fungal	Infection
Ibrexafungerp phosphate is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp phosphate can be used for research of Candida and Aspergillus infections .

HY-P3179

1,3-β-Glucanase	Bacterial	Infection
1,3-β-Glucanase is one of the primary components in C. albicans biofilm extrapolymeric substance (EPS). 1,3-β-Glucanase can degrade β-1,3-glucan so as to disrupt the Candida biofilm matrix and increase the effect of the antimicrobial agent. 1,3-β-Glucanase can be used as an antibiofilm agent .

HY-N14472

Fusacandin B	Fungal	Infection
Fusacandin B inhibits (1,3)-β-glucan synthetase and has antifungal properties .

HY-135141

Tetrahydroechinocandin B L-687901	Fungal	Infection
Tetrahydroechinocandin B (L 687,901) is a potent antifungal agent. Tetrahydroechinocandin B inhibits 1,3-beta-D-glucan synthesis with an IC₅₀ of 0.85 μg/mL .

HY-W050145S2

Levoglucosan-13C6 1,6-Anhydro-β-D-glucopyranose-¹³C₆; 1,6-Anhydro-β-D-glucose-¹³C₆	Endogenous Metabolite	Metabolic Disease
Levoglucosan- ¹³C₆ is the ¹³C labeled Levoglucosan . Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-E71303

*β-Glucan-transporting ATPase*	Biochemical Assay Reagents	Others
β-Glucan-transporting ATPase (EC 7.5.2.3) can be used to investigate the application of β-glucan-transporting ATPase in carbohydrate transport research.

HY-E71152

*1,3-β-D-Glucan* phosphorylase**	Biochemical Assay Reagents	Others
1,3-β-D-Glucan phosphorylase (EC 2.4.1.97) acts on a range of β-1,3-oligoglucans, and on glucans of laminarin type.

HY-N5160

Arborcandin A	Antibiotic Fungal	Infection
Arborcandin A is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin A exhibits IC₅₀** values of 0.25 μg/mL and 0.05 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin A has an MIC of 4-8 μg/mL against the genus Candida .

HY-N5165

Arborcandin F	Antibiotic Fungal	Infection
Arborcandin F is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin F exhibits IC₅₀** values of 0.012 μg/mL against both Candida albicans and Aspergillus fumigatus. Additionally, Arborcandin F has an MIC of 2-4 μg/mL against the genus Candida .

HY-N5163

Arborcandin D	Antibiotic Fungal	Infection
Arborcandin D is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin D exhibits IC₅₀** values of 3 μg/mL and 0.35 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin D has an MIC of 4 μg/mL against the genus Candida .

HY-N5162

Arborcandin C	Antibiotic Fungal	Infection
Arborcandin C is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin C exhibits IC₅₀** values of 0.15 μg/mL and 0.015 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin C has an MIC of 1-2 μg/mL against the genus Candida .

HY-N5161

Arborcandin B	Antibiotic Fungal	Infection
Arborcandin B is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC₅₀** values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida .

HY-N5164

Arborcandin E	Antibiotic Fungal	Infection
Arborcandin E is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin E exhibits IC₅₀** values of 0.1 μg/mL and 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin E has an MIC of 0.5-2 μg/mL against the genus Candida .

HY-17006AS

Caspofungin-d4 MK-0991-d₄; L-743872-d₄	Isotope-Labeled Compounds Fungal Antibiotic Bacterial	Infection
Caspofungin-d₄ (MK-0991-d₄; L-743872-d₄) is a deuterium labeled Caspofungin (HY-17006A). Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-N8537R

Enfumafungin (Standard)	Reference Standards Fungal	Infection
Enfumafungin (Standard) is the analytical standard of Enfumafungin. This product is intended for research and analytical applications. Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis[1][2].

HY-E71154

*1,3-β-Glucan* synthase**	Glycosyltransferase	Metabolic Disease
1,3-β-Glucan synthase (EC 2.4.1.34) belongs to the family of glycosyltransferases, specifically the hexosyltransferases.

HY-P992076

Anti-Candida auris β-1, 3 glucans Antibody (2G8)	TGF-β Receptor TGF-beta/Smad Cholinesterase (ChE) Fungal	Infection Cancer
Anti-Candida auris β-1,3-glucans Antibody (2G8) is an antibody targeting Candida auris β-1,3-glucans, and also acts as an inhibitor of AChE and TGF-β receptor 2. Anti-Candida auris β-1,3-glucans Antibody (2G8) also targets fungal cell wall components, effectively inhibits fungal growth and interferes with capsule formation, thereby significantly reducing the fungal load in mouse tissues. Anti-Candida auris β-1,3-glucans Antibody (2G8) not only blocks TGF-β receptor binding to inhibit the Smad signaling pathway, reduces fibroblast activation and collagen deposition, but also induces epithelial differentiation of tumor cells and reduces pancreatic tumor metastasis. Anti-Candida auris β-1,3-glucans Antibody (2G8) specifically binds to the conserved N-linked glycoepitope on AChE to inhibit its activity without interfering with BChE, and can be used in studies of cryptococcosis and related tumor mechanisms .The isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).

HY-E70928

Laminarinase,Trichoderma sp.	Biochemical Assay Reagents	Metabolic Disease
Laminarinase,Trichoderma sp. (EC 3.2.1.6) degrades β-1,4-glucans of cellulose, xyloglucan and β-1,4-xylan. β-Glucanase represents a group of carbohydrate enzymes which break down glycosidic bonds within beta-glucan.

HY-E71366

Endo-1,4-β-D-glucanase	Glycosidase Endogenous Metabolite	Metabolic Disease
Endo-1,4-β-D-glucanase is a glycoside hydrolase that cleaves internal β-1,4-glycosidic bonds in cellulose and related β-D-glucans (β-D-Glucan) (HY-139413). Endo-1,4-β-D-glucanase randomly cuts long, insoluble cellulose polymer chains into shorter, soluble fragments such as oligosaccharides, thereby paving the way for further digestion into glucose .

Cat. No.	Product Name	Type

HY-W145521

β-1,3-Glucan

1 Publications Verification

β Glucan

Biochemical Assay Reagents

β-1,3-Glucan (β Glucan) is an orally active polysaccharide composed of glucose polymers. β-1,3-Glucan increase the activity of IKKβ kinase, enhances the production of nitric oxide. β-1,3-Glucan improves resistance to Vibrio harveyi infection. β-1,3-Glucan enhances immune response, promotes blood pressure recovery, reduces lung, kidney and liver damage, inhibits the growth of syngeneic tumors .

HY-139413

β-D-Glucan 1 Publications Verification	Biochemical Assay Reagents
β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery . β-d-glucan is an enteric delivery vehicle for probiotics .

Cat. No.	Product Name	Target	Research Area

HY-P3906

Melittin free acid	Fungal Apoptosis Phospholipase Reactive Oxygen Species (ROS)	Infection
Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .

HY-P11003

PTD-N5-1	Toll-like Receptor (TLR)	Inflammation/Immunology
PTD-N5-1 (N5-1) is an IRF5 inhibitory peptide. PTD-N5-1 blocks β-glucan-induced IL-12 production in IFN-γ primed wild-type and Clec2d-difecient bone-marrow-derived dendritic cells (BMDCs). PTD-N5-1 regulates antifungal immunity through suppression of IRF5-mediated IL-12 production .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992076

Anti-Candida auris β-1, 3 glucans Antibody (2G8)	TGF-β Receptor TGF-beta/Smad Cholinesterase (ChE) Fungal	Infection Cancer
Anti-Candida auris β-1,3-glucans Antibody (2G8) is an antibody targeting Candida auris β-1,3-glucans, and also acts as an inhibitor of AChE and TGF-β receptor 2. Anti-Candida auris β-1,3-glucans Antibody (2G8) also targets fungal cell wall components, effectively inhibits fungal growth and interferes with capsule formation, thereby significantly reducing the fungal load in mouse tissues. Anti-Candida auris β-1,3-glucans Antibody (2G8) not only blocks TGF-β receptor binding to inhibit the Smad signaling pathway, reduces fibroblast activation and collagen deposition, but also induces epithelial differentiation of tumor cells and reduces pancreatic tumor metastasis. Anti-Candida auris β-1,3-glucans Antibody (2G8) specifically binds to the conserved N-linked glycoepitope on AChE to inhibit its activity without interfering with BChE, and can be used in studies of cryptococcosis and related tumor mechanisms .The isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-119109

Laminaran 1 Publications Verification	Structural Classification Polysaccharides Microorganisms other families Classification of Application Fields Plants Disease Research Fields Saccharides Source Classification Cancer	Environmental Pollutants Endogenous Metabolite
Laminaran is an *β-1-3-glucan* and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities . Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .

HY-W050145

Levoglucosan 1,6-Anhydro-β-D-glucopyranose; 1,6-Anhydro-β-D-glucose	Natural Products Microorganisms Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-N8537

Enfumafungin	Infection Triterpenes Microorganisms Classification of Application Fields Terpenoids Disease Research Fields Source Classification	Fungal
Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis .

HY-N15135

Arabinoxylan (Medium viscosity)	Structural Classification Polysaccharides Antibiotics Leguminosae Pisum sativum Linn Plants Saccharides Other Antibiotics Source Classification	Interleukin Related Toll-like Receptor (TLR) Fungal
Arabinoxylan Medium viscosity is an orally active Dectin-1 splice variant modulator, glucose absorption inhibitor, and chyme viscosity enhancer. Arabinoxylan Medium viscosity inhibits particulate β-glucan-induced Dectin-1A activation and mildly suppresses Dectin-1B activation. In human dendritic cells stimulated with particulate β-glucan, Arabinoxylan Medium viscosity reduces the production of IL-10 and TNF-α, and increases the production of IL-4 and IL-23. Arabinoxylan Medium viscosity also supports antifungal immune responses without activating TLR2, TLR4 or TLR5, and does not induce cytokine production when used to stimulate human dendritic cells alone. Arabinoxylan Medium viscosity increases small intestinal chyme viscosity, gets degraded in the large intestine to produce short-chain fatty acids, reduces glucose absorption and insulin response, and improves glucose homeostasis. Arabinoxylan Medium viscosity supports microbial fermentation and the growth of beneficial microbiota in the gastrointestinal tract, prevents bile acid reabsorption, and delays starch digestion. Arabinoxylan Medium viscosity can be used in research related to type 2 diabetes, impaired glucose tolerance, and metabolic syndrome .

HY-N6924

Zingibroside R1 1 Publications Verification	Infection Structural Classification Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Classification of Application Fields Panax japonicas C. A. Mey. Metabolic Disease Plants Disease Research Fields Saccharides Araliaceae Source Classification	HIV PIN1 Fungal GLUT Reactive Oxygen Species (ROS)
Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .

HY-125723

Echinocandin B SL 7810; A-30912 A	Structural Classification Monophenols Microorganisms Phenols Source Classification	Endogenous Metabolite Fungal Antibiotic
Echinocandin B (SL 7810) is a lipopeptide antifungal antibiotic. Echinocandin B is produced by Aspergillus nidulans. Echinocandin B inhibits *β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B exhibits activity against a variety of Aspergillus species .

HY-W050145R

Levoglucosan (Standard) 1,6-Anhydro-β-D-glucopyranose (Standard); 1,6-Anhydro-β-D-glucose (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Levoglucosan (Standard) is the analytical standard of Levoglucosan. This product is intended for research and analytical applications. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-N14472

Fusacandin B	Microorganisms Antibiotics Other Antibiotics Source Classification	Fungal
Fusacandin B inhibits (1,3)-β-glucan synthetase and has antifungal properties .

HY-N5160

Arborcandin A	Natural Products Microorganisms Source Classification	Antibiotic Fungal
Arborcandin A is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin A exhibits IC₅₀** values of 0.25 μg/mL and 0.05 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin A has an MIC of 4-8 μg/mL against the genus Candida .

HY-N5165

Arborcandin F	Natural Products Microorganisms Source Classification	Antibiotic Fungal
Arborcandin F is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin F exhibits IC₅₀** values of 0.012 μg/mL against both Candida albicans and Aspergillus fumigatus. Additionally, Arborcandin F has an MIC of 2-4 μg/mL against the genus Candida .

HY-N5163

Arborcandin D	Natural Products Microorganisms Source Classification	Antibiotic Fungal
Arborcandin D is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin D exhibits IC₅₀** values of 3 μg/mL and 0.35 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin D has an MIC of 4 μg/mL against the genus Candida .

HY-N5162

Arborcandin C	Natural Products Microorganisms Source Classification	Antibiotic Fungal
Arborcandin C is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin C exhibits IC₅₀** values of 0.15 μg/mL and 0.015 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin C has an MIC of 1-2 μg/mL against the genus Candida .

HY-N5161

Arborcandin B	Structural Classification Microorganisms Antibiotics Source Classification	Antibiotic Fungal
Arborcandin B is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC₅₀** values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida .

HY-N5164

Arborcandin E	Natural Products Microorganisms Source Classification	Antibiotic Fungal
Arborcandin E is a *1,3-β-glucan* synthase inhibitor that serves as an antifungal antibiotic. Arborcandin E exhibits IC₅₀** values of 0.1 μg/mL and 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin E has an MIC of 0.5-2 μg/mL against the genus Candida .

HY-N8537R

Enfumafungin (Standard)	Triterpenes Microorganisms Terpenoids Source Classification	Reference Standards Fungal
Enfumafungin (Standard) is the analytical standard of Enfumafungin. This product is intended for research and analytical applications. Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis[1][2].

HY-125723A

Echinocandin B (purity>85%) SL 7810 (purity>85%); A-30912 A (purity>85%)	Structural Classification Monophenols Microorganisms Phenols Source Classification	Antibiotic Fungal Endogenous Metabolite
Echinocandin B (purity>85%) (SL 7810 (purity>85%)) is a lipopeptide antifungal antibiotic. Echinocandin B (purity>85%) is produced by Aspergillus nidulans. Echinocandin B (purity>85%) inhibits *β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>85%) exhibits activity against a variety of Aspergillus species .

HY-125723B

Echinocandin B (purity>65%) SL 7810 (purity>65%); A-30912 A (purity>65%)	Structural Classification Monophenols Microorganisms Phenols Source Classification	Antibiotic Fungal Endogenous Metabolite
Echinocandin B (purity>65%) (SL 7810 (purity>65%)) is a lipopeptide antifungal antibiotic. Echinocandin B (purity>65%) is produced by Aspergillus nidulans. Echinocandin B (purity>65%) inhibits *β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>65%) exhibits activity against a variety of Aspergillus species .

Species:	Human (3) Mouse (1)
Tag:	Tag Free (1) Fc (3)
Source:	HEK293 (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P700694

	Dectin-1/CLEC7A Protein, Mouse (HEK293, Fc) Beta-Glucan receptor; DC-associated C-type lectin 1; Dectin-1; Dectin1; CD369; BGR; CLECSF12; DECTIN1; CANDF4	Mouse	HEK293
	Dectin-1/CLEC7A acts as a lectin and specifically recognizes β-1,3-linked and β-1,6-linked glucans in bacterial and fungal cell walls. Dectin-1/CLEC7A is critical for Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting SYK through its immunoreceptor tyrosine-based activation motif (ITAM), thereby activating NF-kappa-B. Dectin-1/CLEC7A Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P70101

	Dectin-1/CLEC7A Protein, Human (HEK293, Fc) 1 Publications Verification rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-Glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; DECTIN1CANDF4	Human	HEK293
	The Dectin-1/CLEC7A protein is a lectin and pattern recognition receptor that targets β-1,3- and β-1,6-linked glucans in bacterial and fungal cell walls. It triggers Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting splenic tyrosine kinase (SYK) and activating the CARD domain-BCL10-MALT1 (CBM) signalosome. Dectin-1/CLEC7A Protein, Human (HEK293, Fc) is the recombinant human-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P704035

	Dectin-1/CLEC7A Protein, Human (HEK293) rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-Glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; DECTIN1CANDF4	Human	HEK293
	The Dectin-1/CLEC7A protein is a lectin and pattern recognition receptor that targets β-1,3- and β-1,6-linked glucans in bacterial and fungal cell walls. It triggers Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting splenic tyrosine kinase (SYK) and activating the CARD domain-BCL10-MALT1 (CBM) signalosome. Dectin-1/CLEC7A Protein, Human (HEK293) is the recombinant human-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with no tag.

HY-P704036

	Dectin-1/CLEC7A Protein, Human (HEK293, hFc) rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-Glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; DECTIN1CANDF4	Human	HEK293
	The Dectin-1/CLEC7A protein is a lectin and pattern recognition receptor that targets β-1,3- and β-1,6-linked glucans in bacterial and fungal cell walls. It triggers Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting splenic tyrosine kinase (SYK) and activating the CARD domain-BCL10-MALT1 (CBM) signalosome. Dectin-1/CLEC7A Protein, Human (HEK293, hFc) is the recombinant human-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with hFc tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-W050145S

Levoglucosan-d7
Levoglucosan-d₇ is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-17006S

Caspofungin-d4 diacetate
Caspofungin-d₄ (acetate) is the deuterium labeled Caspofungin diacetate . Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-W050145S2

Levoglucosan-13C6
Levoglucosan- ¹³C₆ is the ¹³C labeled Levoglucosan . Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-17006AS

Caspofungin-d4
Caspofungin-d₄ (MK-0991-d₄; L-743872-d₄) is a deuterium labeled Caspofungin (HY-17006A). Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P89743

	Dectin-1 Antibody (YA9087) Beta-Glucan receptor, Bgr, CD369, Clec7a, Clecsf12	WB	mouse
	Dectin-1 Antibody (YA9087) is a Rat-derived and non-conjugated IgG2b monoclonal antibody, targeting to Dectin-1.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

β Glucan

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
Products