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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
AVE1330A
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "AVE1330A" in MCE Product Catalog:
95
95 Publications Verification
Synonyms: NXL-104; AVE1330A
Target:
Research Areas:
Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
95
95 Publications Verification
Synonyms: NXL-104 free acid; AVE1330A free acid
Target:
Research Areas:
Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
95
95 Publications Verification
Synonyms: NXL-104 hydrate; AVE1330A hydrate
Target:
Research Areas:
Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
Cat. No.: HY-14879C
Synonyms: NXL-104 dihydrate; AVE1330A dihydrate
Target:
Research Areas:
Avibactam sodium (NXL-104) dihydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
Cat. No.: HY-14879E
CAS No.: 1383814-68-3
Synonyms: ent-NXL-104; ent-AVE1330A
Target:
Research Areas:
Ent-Avibactam (NXL-104) sodium is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime (HY-B0593), rel-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC50 value of rel-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid (HY-A0256) and Ticarcillin (HY-139805), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes .
Cat. No.: HY-14879D
CAS No.: 396731-20-7
Synonyms: rel-NXL-104; rel-AVE1330A
Target:
Research Areas:
rel-Avibactam sodium (rel-NXL-104) is an isomer of Avibactam (HY-14879). Avibactam is a β-lactamase inhibitor with an IC50 of 8 nM against TEM-1 β-lactamase and an IC50 of 80 nM against P99 β-lactamase. Avibactam exhibits no significant intrinsic antibacterial activity when used alone. Avibactam restores the activity of Ceftazidime (HY-B0593) against β-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Avibactam does not enhance the activity of Ceftazidime against Acinetobacter spp., Burkholderia spp., or most anaerobic Gram-negative bacilli. Avibactam is used in research related to Gram-negative bacterial infections .
Cat. No.: HY-187660
CAS No.: 396731-14-9
Synonyms: rel-NXL-104 free acid; rel-AVE1330A free acid
Target:
Research Areas:
rel-Avibactam (rel-NXL-104 free acid) is an isomer of Avibactam (HY-14879). Avibactam is a β-lactamase inhibitor with an IC50 of 8 nM against TEM-1 β-lactamase and an IC50 of 80 nM against P99 β-lactamase. Avibactam exhibits no significant intrinsic antibacterial activity when used alone. Avibactam restores the activity of Ceftazidime (HY-B0593) against β-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Avibactam does not enhance the activity of Ceftazidime against Acinetobacter spp., Burkholderia spp., or most anaerobic Gram-negative bacilli. Avibactam is used in research related to Gram-negative bacterial infections .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
