22 Results for "

27-hydroxycholesterol

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "27-hydroxycholesterol" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-17365
CAS No.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
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10
10 Cited Publications
Cat. No.: HY-N2371
CAS No.: 20380-11-4
Synonyms: 27-OHC
27-Hydroxycholesterol (27-OHC) is a selective estrogen receptor modulator and an agonist of the liver X receptor.
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1
1 Cited Publications
Cat. No.: HY-105055
CAS No.: 77327-05-0
Purity:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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Cat. No.: HY-134124
CAS No.: 92614-59-0
Purity:  95.8%
Research Areas:  

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
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Cat. No.: HY-125586
CAS No.: 21150-22-1
Purity:  ≥96.0%
Research Areas:  

Cancer

β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-176497
CAS No.: 1713317-28-2
Synonyms: G297X
Target:  

Cytochrome P450

Research Areas:  

Metabolic Disease Cancer

GW273297X is a selective CYP27A1 inhibitor. GW273297X blocks 27-hydroxycholesterol biosynthesis and sterol product formation in human macrophages. GW273297X reduces cancer cells colonization by inhibiting pro-metastatic effects of 27-hydroxycholesterol. GW273297X can be used for the researches of cancer and metabolic disease, such as breast cancer .
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Cat. No.: HY-N2371R
CAS No.: 20380-11-4
Synonyms: 27-OHC (Standard)
27-Hydroxycholesterol (27-OHC) is a selective estrogen receptor modulator and an agonist of the liver X receptor.
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Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
Target:  

Phospholipase Fungal

Research Areas:  

Infection

Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold [1][2].
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Cat. No.: HY-N15953
CAS No.: 3056013-53-4
Category:  

Lipids

Target:  

Drug Metabolite

27-Hydroxy oncosterone is a metabolite that inhibits breast cancer (BC) cell proliferation and blocks oncosterone and 27-Hydroxycholesterol (HY-N2371)-induced proliferation in BC cells .
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Cat. No.: HY-P4755
CAS No.: 282726-24-3
Research Areas:  

Others

N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide composed of L-phenyleline and L-leucine bound to aniline groups. N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide can be used to quantitatively determine the N-terminal heme adduct formed upon exposure to propylene oxide (PO) .
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Cat. No.: HY-P3100
CAS No.: 939960-34-6
Target:  

Parasite

Research Areas:  

Infection

Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
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Cat. No.: HY-125357
CAS No.: 148619-41-4
Target:  

Peptides

Research Areas:  

Metabolic Disease

Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes .
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Cat. No.: HY-W414581
CAS No.: 240129-30-0
Synonyms: 3ß,27-Dihydroxy-5-cholesten-7-one
7-Keto-27-hydroxycholesterol (3?,27-Dihydroxy-5-cholesten-7-one) is an important bioactive compound that agonizes the activity of smoothened (SMO) protein in the Hedgehog (Hh) signaling pathway, which is essential for proper cell differentiation in embryonic tissues.
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Cat. No.: HY-158104
Target:  

ATF6

Research Areas:  

Others

LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
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Cat. No.: HY-P2424
CAS No.: 144396-38-3
Synonyms: CCK-J
Target:  

Calcium Channel

Research Areas:  

Others

Cholecystokinin-J (CCK-J), a cholecystokinin, stimulates Ca 2+ release .
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Cat. No.: HY-P10872
Target:  

SARS-CoV

Research Areas:  

Infection

P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC50s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC50 of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models .
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Cat. No.: HY-P10906
CAS No.: 2868285-05-4
Research Areas:  

Others

Talovirtide is a peptide containing L-valyl .
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Cat. No.: HY-P11455
Target:  

Liposome

Research Areas:  

Others

Lipopeptide CPE4 is a PEG-modified peptide E4 [(EIAALEK) 4]. Lipopeptide CPE4 is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 can be used for drug delivery research .
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Cat. No.: HY-P11766
Synonyms: GALA-cholesterol
Research Areas:  

Cancer

GALA-chol is a cholesterol-conjugated pH-responsive fusion peptide that can serve as a delivery adjuvant. GALA-chol enhances the endocytosis of siRNA RET/PTC1-SQ nanoparticles, inhibits cell viability, and undergoes pH-responsive charge conversion in the acidic lysosomal environment, thereby promoting lysosomal escape of small extracellular vesicle (sEV) cargo. GALA-chol anchors to the sEV membrane and maintains the structural integrity and intrinsic homing activity of sEVs. GALA-chol can be used in studies related to adjuvant delivery .
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Cat. No.: HY-P11783
CAS No.: 86711-55-9
Target:  

Fungal

Research Areas:  

Infection

Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .
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