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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
AHH
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "AHH" in MCE Product Catalog:
Synonyms: Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin
Category:
Pterogyne nitens Tul. Alkaloids Erinacea anthyllis Link Pyrrole Alkaloids Metabolic Disease Plants Compositae Disease Research Fields
Target:
Cat. No.: HY-N4205
CAS No.: 23434-88-0
Category:
Alkaloids Piperidine Alkaloids Piperaceae Plants Disease Research Fields Piper nigrum Linn. Cancer
Target:
Cat. No.: HY-RS16533
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Research Areas:
Ahr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ahr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W762018
CAS No.: 60851-34-5
Synonyms: 2,3,4,6,7,8-HxCDF
Target:
2,3,4,6,7,8-Hexachlorodibenzofuran (2,3,4,6,7,8-HxCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 2,3,4,6,7,8-Hexachlorodibenzofuran induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 0.687 and 0.575 nM, respectively) .
Cat. No.: HY-W762015
CAS No.: 57117-44-9
Synonyms: 1,2,3,6,7,8-HxCDF
Target:
Research Areas:
1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 1,2,3,6,7,8-Hexachlorodibenzofuran induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 1.47 and 1.24 nM, respectively). 1,2,3,6,7,8-Hexachlorodibenzofuran reduces weight, induces thymic atrophy, and induces the expression of genes encoding the cytochrome P450 (CYP) isoform CYP1A1 and 4-chlorobiphenyl hydroxylase in rats (EC50s = 3.2, 0.9, 0.35, and 0.21 µmol/kg, respectively) .
Cat. No.: HY-RS00484
Target:
Research Areas:
AHRR Human Pre-designed siRNA Set A contains three designed siRNAs for AHRR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Synonyms: Senecionan-11,16-dione, 12-hydroxy- (Standard); Aureine (Standard); Senecionin (Standard)
Category:
Pterogyne nitens Tul. Alkaloids Erinacea anthyllis Link Pyrrole Alkaloids Plants Compositae
Target:
Cat. No.: HY-N4205R
CAS No.: 23434-88-0
Target:
Cat. No.: HY-RS03441
Target:
Research Areas:
CYP1A1 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP1A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-173309
Research Areas:
P53/TLR2 modulator-1 (Compound Z9) is a modulator that targets both the P53 pathway and TLR2 simultaneously, exhibiting anti-radiation activity. P53/TLR2 modulator-1 reduces apoptosis by inhibiting the radiation-induced expression of P53 and Bax. At the same time, it activates the TLR2 pathway, upregulates the expression of downstream proteins MyD88 and P65, and promotes the secretion of cytokines such as IL-6, thus exerting an anti-radiation effect. P53/TLR2 modulator-1 shows significant anti-radiation activity against both AHH-1 cells and HUVECs. It can also increase the survival rate of C57BL/6J mice irradiated with a lethal dose of radiation and reduce the damage to their hematopoietic system, the villous structure of the small intestine, and the spleen caused by radiation. P53/TLR2 modulator-1 can be used in the research of radiation injury-related diseases .
Cat. No.: HY-W517092
CAS No.: 55673-89-7
Synonyms: 1,2,3,4,7,8,9-HpCDF
Research Areas:
1,2,3,4,7,8,9-Heptachlorodibenzofuran (1,2,3,4,7,8,9-HpCDF) is a compound that induces the expression of CYP1A1 and CYP1B1 genes in human peripheral blood lymphocytes, while also promoting the expression of the aryl hydrocarbon receptor repressor (AhRR). 1,2,3,4,7,8,9-Heptachlorodibenzofuran can increase ethoxyresorufin-O-deethylase (EROD) activity in isolated human peripheral blood lymphocytes in a concentration-dependent manner, which serves as a marker of CYP1A1 activity. Furthermore, 1,2,3,4,7,8,9-Heptachlorodibenzofuran exhibits immunosuppressive effects by reducing the number of splenic plaque-forming cells in mice and increasing aryl hydrocarbon hydroxylase (AHH) activity in liver microsomes of mice injected with sheep red blood cells. 1,2,3,4,7,8,9-Heptachlorodibenzofuran can be used in research in the fields of immunology, metabolic diseases, and environmental toxicology .
Cat. No.: HY-RS16737
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Research Areas:
Cyp1a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cyp1a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W100681R
CAS No.: 1450-72-2
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Research Areas:
Tetrahydropiperine (Standard) is the analytical standard of Tetrahydropiperine. This product is intended for research and analytical applications. Tetrahydropiperine, a cyclohexyl analogue of piperine, is the first natural aryl pentanamide from Piper longum . Tetrahydropiperine (compound 14) inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH; IC50=23 µM) .
Cat. No.: HY-RS23174
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Research Areas:
Cyp1a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cyp1a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
