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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
AM0216
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "AM0216" in MCE Product Catalog:
Cat. No.: HY-117222
CAS No.: 1202764-61-1
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AM-0216 is a selective NIK inhibitor (Ki 2.0 nM) that acts on the non-canonical NF‑κB signaling pathway. AM‑0216 selectively inhibits NIK-dependent NF‑κB activation, reduces RelB:p52 activity, and inhibits BAFF receptor-induced NF‑κB activity. AM‑0216 induces apoptosis and NIK-dependent cytotoxicity in myeloma cells, inhibits cell clonogenic formation, and suppresses tumor growth in B-cell malignancies with constitutive NIK activation. AM-0216 can be used for research on mantle cell lymphoma, multiple myeloma, and B-cell malignancies .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
