2. NF-κB
  3. NF-κB
  4. AM-0216

AM-0216 is a highly selective NF-κB-inducing kinase (NIK) inhibitor with a Ki value of 2 nM. AM-0216 is promising for research of NF-κB-dependent hematologic malignancies (e.g., multiple myeloma) and autoimmune diseases.

For research use only. We do not sell to patients.

AM-0216

AM-0216 Chemical Structure

CAS No. : 1202764-61-1

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AM-0216 Related Antibodies

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Description

AM-0216 is a highly selective NF-κB-inducing kinase (NIK) inhibitor with a Ki value of 2 nM. AM-0216 is promising for research of NF-κB-dependent hematologic malignancies (e.g., multiple myeloma) and autoimmune diseases[1].

Molecular Weight

363.44

Formula

C19H17N5OS
CAS No.
SMILES

C(#C[C@@](C)(O)C1=NC=CS1)C=2C=C3N(CCC3=CC2)C4=NC(N)=NC=C4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AM-0216 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AM-02161202764-61-1AM0216AM 0216NF-κBNuclear factor-κBNuclear factor-kappaBNIKhematologic malignanciesautoimmune diseasesInhibitorinhibitorinhibit

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