2 Results for "

ATAC complex

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ATAC complex" in MCE Product Catalog:

Cat. No.: HY-181065
CAS No.: 3099617-79-2
Research Areas:  

Cancer

LS-170 is a YEATS2 YEATS domain inhibitor with an IC50 of 0.14 μM. LS-170 displays selectivity for the YEATS2 YEATS domain over other YEATS domain family members and other epigenetic 'reader' and 'eraser' proteins. LS-170 reduces chromatin occupancy of the Ada-two-A-containing (ATAC) complex, decreases ATAC-dependent histone acetylation levels, and downregulates expression of ATAC-governed genes. LS-170 suppresses tumor growth in a lung cancer mouse model. LS-170 can be used for the research of non-small cell lung cancer .
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Cat. No.: HY-P705550
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KAT14; CSRP2-Binding Protein; Prev. CSRP2BP; Cysteine Rich Protein 2 Binding Protein; CRP2BP; ATAC Component 2 Homolog (Drosophila); ATAC2; ATAC Component 2 Homolog; Cysteine-Rich Protein 2-Binding Protein; CSRP2 Binding Protein; ADA2A-Containing complex
Species:  
Human
Source:  
E. coli
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