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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
Adamantane
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "Adamantane" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W395779
CAS No.: 1335113-30-8
EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM .
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Natural Products Psidium guajava Linn. Other Diseases Myrtaceae Plants Disease Research Fields
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Cat. No.: HY-W016473
CAS No.: 828-51-3
Cat. No.: HY-W016287
CAS No.: 99181-50-7
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Adamantane-1,3,5-triol is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-W009807
CAS No.: 707-36-8
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1-Chloro-3,5-dimethyladamantane is an Adamantane (HY-N2427) derivative.
Cat. No.: HY-B1044
CAS No.: 20098-14-0
Synonyms: Kemantane; 5-Hydroxy-2-adamantanone
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Idramantone (Kemantane, 5-Hydroxy-2-adamantanone) is an Adamantane derivative. Idramantone is an immunostimulant. Idramantone is a versatile starting material for the synthesis of various adamantine deivatives. Idramantone can be produced using P450cam monooxygenase coupled with NADH regeneration as an oxidation biocatalyst. Idramantone can be studied in research on bronchial pathology .
Cat. No.: HY-118998
CAS No.: 1603845-42-6
TX2-121-1 is a potent and selective Her3 (ErbB3) degrader that contains a hydrophobic adamantane moiety. TX2-121-1 has an IC50 of 49 nM for Her3. TX2-121-1 inhibits Her3-dependent signaling and heterodimerization of Her3. TX2-121-1 has the ability to inhibit cell proliferation. TX2-121-1 can be used in the study of tumors. (Pink: Her3 inhibitor (HY-164988); Black: Linker; Blue: Adamantane (HY-N2427)) .
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IEM-1754, a dicationic adamantane derivative, is a potent blocker of open channels of native ionotropic glutamate receptors including quisqualate-sensitive receptors in insect muscles, NMDAR in cultured rat cortical neurons, and AMPAR in freshly isolated hippocampal cells. IEM-1754 shows anticonvulsant potency in vivo .
Cat. No.: HY-N2427S
CAS No.: 30470-60-1
Cat. No.: HY-W016473S
CAS No.: 33830-12-5
Cat. No.: HY-172769
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CM112 is a selective protein arginine methyltransferase 1 (PRMT1) degrader by tethering hydrophobic tag, adamantane, to MS023 with a 5-PEG linker. CM112 induces the degradation of PRMT1 in various solid cancer cell lines. CM112 can also target the nonenzymatic function of PRMT1 by downregulating the stability of the orphan receptor TR3. CM112 is promising for research of cancers .
Cat. No.: HY-W451406B
CAS No.: 956496-54-1
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NH2-PEG1000-NH2 is a PEG (MW = 1000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
Cat. No.: HY-161933
CAS No.: 2860813-92-7
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1-Adamantane-amide-C7-NH2 is the linker, which can be used for syntheisis of PROTAC GPX4 degrader-3 (HY-161930) .
Cat. No.: HY-W100063
CAS No.: 702-79-4
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1,3-Dimethyladamantane is a impurity of adamantane.
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Adamantane is a compound used in the synthesis of N-Boc-1,2,4-trioxane .
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1-Iodoadamantane is a 1-substituted adamantane derivative. On a silver electrode in aprotic solvents, 1-Iodoadamantane can be reduced to form a mixture of adamantane and 1,1'-biadamantane without insonation, while only adamantane is formed under the action of 10 kHz insonation .
Cat. No.: HY-168682
CAS No.: 31685-38-8
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Adamantane-Butyl alcohol is a selective and persistent degrader targeting the CDK8-cyclin C complex. Adamantane-Butyl alcohol is the linker for LL-K8-22 (PROTAC CDK8-cyclin C, HY-149209) and HyT .
Cat. No.: HY-W674002
CAS No.: 101055-70-3
Synonyms: 1-(2-Phosphaethynyl)Adamantane
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1-Adamantylphosphaethyne (1-(2-Phosphaethynyl)adamantane) is a compound with potential biological activity and can be used as a catalyst in organic synthesis. 1-Adamantylphosphaethyne has shown the ability to induce cell apoptosis in compound development, which helps in anti-tumor inhibition. 1-Adamantylphosphaethyne can also be used as an efficient reaction intermediate to promote the progress of various chemical reactions.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
