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Results for "

Adt pharma ras Inhibitors

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Ras (110) Akt (1) Aminoacyl-tRNA Synthetase (1) Angiotensin Receptor (3) Angiotensin-converting Enzyme (ACE) (3) Antibiotic (2) Apoptosis (23) Autophagy (8) Cyclin G-associated Kinase (GAK) (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) EGFR (1) Endogenous Metabolite (10) ERK (10) Farnesyl Transferase (18) Ferroptosis (1) FLT3 (1) Fungal (1) Glutathione Peroxidase (1) HDAC (3) HIF/HIF Prolyl-Hydroxylase (1) Histone Demethylase (2) ICMT (60) MAGL (1) MAPKAPK2 (MK2) (1) MDM-2/p53 (1) MEK (4) MMP (1) Molecular Glues (1) Monoamine Oxidase (1) NOD-like Receptor (NLR) (1) p38 MAPK (2) Phosphatase (1) Phosphodiesterase (PDE) (4) Phospholipase (2) PI3K (1) PKC (1) PROTAC Linkers (3) PROTACs (5) Raf (9) RET (1) ROR (1) ROS Kinase (1) SHP2 (3) STK33 (1) Target Protein Ligand-Linker Conjugates (6) Tyrosinase (1) Wnt (2) β-catenin (2)
By Research Areas:	Cancer (232) Cardiovascular Disease (10) Endocrinology (2) Infection (9) Inflammation/Immunology (9) Metabolic Disease (2) Neurological Disease (3)
Click Chemistry:	Alkynes (2)

248

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: Ras

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-109582

ADT-OH 1 Publications Verification 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1	Apoptosis	Cancer
ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. ADT-OH has the potential for the research of cancer diseases .

HY-138294

RAS/RAS-RAF-IN-1 1 Publications Verification	Ras Raf	Cancer
RAS/RAS-RAF-IN-1 is a potent *RAS* and *RAS-RAF* inhibitor. RAS/RAS-RAF-IN-1 has a K_D of 5.0 μΜ-15 μΜ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity .

HY-18674

*K-Ras-IN-1*	Ras	Cancer
K-Ras-IN-1 is a *K-Ras* inhibitor. K-Ras-IN-1 binds K-Ras (WT), K-Ras (G12D), K-Ras (G12V), and H-Ras. K-Ras-IN-1 has the potential to be used in research on pancreatic, colon and lung cancer .

HY-157887

ADT-007	Ras	Cancer
ADT-007 is a potent and orally active pan-RAS inhibitor with strong anticancer effects. ADT-007 binds RAS in a nucleotide-free conformation to block GTP activation. ADT-007 potently and selectively inhibits the growth of cancer cells with mutated or hyper-activated wild-type RAS isozymes .

HY-148878

Ras modulator-1

Ras Cancer

Ras modulator-1 is a modulator of Ras. Ras modulator-1 is an active compound extracted from patent US20120302581 .
HY-101295

Pan-RAS-IN-1

5 Publications Verification

Ras Cancer

Pan-RAS-IN-1 is a pan-Ras inhibitor that disrupts the interaction of Ras proteins and their effectors.
HY-P2157

Ras Inhibitory Peptide

Ras Cancer

Ras Inhibitory Peptide (VPPPVPPRRR) is a Ras inhibitor with antitumor activity .

Ras modulator-1	Ras	Cancer
Ras modulator-1 is a modulator of *Ras. Ras* modulator-1 is an active compound extracted from patent US20120302581 .

*Pan-RAS-IN-1* 5 Publications Verification	Ras	Cancer
Pan-RAS-IN-1 is a *pan-Ras* inhibitor that disrupts the interaction of Ras proteins and their effectors.

Ras Inhibitory Peptide	Ras	Cancer
Ras Inhibitory Peptide (VPPPVPPRRR) is a *Ras* inhibitor with antitumor activity .

HY-122862

RAS inhibitor Abd-7 1 Publications Verification	Ras	Cancer
RAS inhibitor Abd-7, a potent RAS-binding compound (K_d=51 nM), is a RAS-effector protein-protein interaction (PPI) inhibitor. RAS inhibitor Abd-7 interacts with RAS inside the cells, prevents RAS-effector interactions and inhibits endogenous RAS-dependent signaling. RAS inhibitor Abd-7 impairs the PPI of various mutant KRAS proteins with PI3K, CRAF and RALGDS as well as NRAS Q61H and HRAS G12V .

HY-156363

K-Ras-IN-2

Ras Cancer

K-Ras-IN-2 (Compound CHI-000-667) is a K-Ras antagonist, and can be used for tumor research .

*K-Ras-IN-2*	Ras	Cancer
K-Ras-IN-2 (Compound CHI-000-667) is a *K-Ras* antagonist, and can be used for tumor research .

HY-115555

*K-Ras-PDEδ-IN-1*	Phosphodiesterase (PDE)	Cancer
K-Ras-PDEδ-IN-1 is a novel and potent competitive *K-Ras-PDEδ* inhibitor. K-Ras-PDEδ-IN-1 binds to the farnesyl binding pocket of PDEδ with a low nanomolar K_d of 8 nM .

HY-129523

*PROTAC K-Ras* Degrader-1** 1 Publications Verification	PROTACs Ras	Cancer
PROTAC K-Ras Degrader-1 (Compound 518) is a PROTAC. PROTAC K-Ras Degrader-1 can effectively degrades *K-Ras* based on Cereblon E3 ligand, exhibits ≥70% degradation efficacy in SW1573 cells .

HY-18605

K-Ras G12C-IN-2

Ras Cancer

K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor.

*K-Ras* G12C-IN-2**	Ras	Cancer
K-Ras G12C-IN-2 is an irreversible covalent *K-Ras* G12C** inhibitor.

HY-129775

*K-Ras* ligand-Linker Conjugate 1**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 1 incorporates a ligand for *K-Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras* ligand-Linker Conjugate 1 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells .

HY-129776

*K-Ras* ligand-Linker Conjugate 2**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 2 incorporates a ligand for *K-Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras* ligand-Linker Conjugate 2 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells .

HY-18606

K-Ras G12C-IN-3

Ras Cancer

K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.

*K-Ras* G12C-IN-3**	Ras	Cancer
K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.

HY-130707

*K-Ras* ligand-Linker Conjugate 3**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells .

HY-130822

*K-Ras* ligand-Linker Conjugate 4**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 4 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 4 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells .

HY-130823

*K-Ras* ligand-Linker Conjugate 5**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 5 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 5 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells .

HY-130991

*K-Ras* ligand-Linker Conjugate 6**	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 6 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 6 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells .

HY-129189

RAS GTPase inhibitor 1	Ras	Cancer
RAS GTPase inhibitor 1 (example 51) is a RAS GTPase inhibitor with anti-tumor activity, extracted from patent WO2018212774A1. RAS GTPase inhibitor 1 (example 51) exhibits an EC₅₀ less than 1 μM for at least one nucleotide exchange and an IC₅₀ less than 1 μM in H727 cells .

HY-12446

K-Ras(G12C) inhibitor 9

Ras Cancer

K-Ras (G12C) inhibitor 9 is an allosteric inhibitor of the K-Ras (G12C) .
HY-18604

K-Ras G12C-IN-1

Ras Cancer

K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1.
HY-18707

K-Ras(G12C) inhibitor 12

Ras Apoptosis Cancer

K-Ras(G12C) inhibitor 12 is a K-Ras(G12C) inhibitor. K-Ras(G12C) inhibitor 12 acts on H1792 cells with an EC50 of 0.32 μM.
HY-107841

K-Ras(G12C) inhibitor 6

Ras Cancer

K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) .

*K-Ras(G12C) inhibitor 9*	Ras	Cancer
K-Ras (G12C) inhibitor 9 is an allosteric inhibitor of the K-Ras (G12C) .

*K-Ras* G12C-IN-1**	Ras	Cancer
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1.

*K-Ras(G12C) inhibitor 12*	Ras Apoptosis	Cancer
K-Ras(G12C) inhibitor 12 is a K-Ras(G12C) inhibitor. K-Ras(G12C) inhibitor 12 acts on H1792 cells with an EC50 of 0.32 μM.

*K-Ras(G12C) inhibitor 6*	Ras	Cancer
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the *K-Ras(G12C)* .

HY-128044

Ftase inhibitor I B581	Farnesyl Transferase	Cancer
Ftase inhibitor I (B581) is a potent, selective and peptidomimetic farnesyl transferase (FTase) inhibitor. Ftase inhibitor I shows selectivity for FTase over geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras) .

HY-148439

RMC-6236

ras-IN-2
Ras Cancer

RMC-6236 (Compound A122) is a potent RAS(ON) ^MULTI inhibitor and can be used for the research of cancer .

RMC-6236 ras-IN-2	Ras	Cancer
RMC-6236 (Compound A122) is a potent RAS(ON) ^MULTI inhibitor and can be used for the research of cancer .

HY-155954

UCM-1336	Apoptosis Autophagy	Cancer
UCM-1336 is a potent ICMT inhibitor, with an IC₅₀ of 2 μM. UCM-1336 induces mislocalization of endogenous Ras, decreases Ras activation and induces cell death by autophagy and apoptosis .

HY-124306

ML-099 2 Publications Verification CID-888706	Ras	Cancer
ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, *Ras, Rab7, and Rab-2A* .

HY-128771

K-Ras G12C-IN-4

Ras Cancer

K-Ras G12C-IN-4, compound 1, is a potent Covalent Inhibitor of KRAS ^G12C .

*K-Ras* G12C-IN-4**	Ras	Cancer
K-Ras G12C-IN-4, compound 1, is a potent Covalent Inhibitor of KRAS ^G12C .

HY-123673

MCP110 1 Publications Verification	Ras Raf	Cancer
MCP110 is an inhibitor of *Ras/Raf-1* interaction. MCP110 blocks the interaction of Ras with Raf. MCP110 disrupts this interaction might can be used for the research of human tumors .

HY-14718

Resminostat ras2410; 4SC-201	HDAC	Cancer
Resminostat (RAS2410; 4SC-201) is a potent inhibitor of HDAC1, HDAC3 and HDAC6, with mean IC₅₀ values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC₅₀ of 877 nM.

HY-147229

GDC-6036-NH

Ras Cancer

GDC-6036-NH is from patent WO2020097537A2, and a precursor of compound 17 a/b. Compound 17 a/b is a RAS inhibitor and can be used in cancer research .

GDC-6036-NH	Ras	Cancer
GDC-6036-NH is from patent WO2020097537A2, and a precursor of compound 17 a/b. Compound 17 a/b is a *RAS* inhibitor and can be used in cancer research .

HY-W048303

L-Azatyrosine	Antibiotic	Infection Cancer
L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes .

HY-129273

L-731735

Farnesyl Transferase Cancer

L-731735 is a selective FPTase inhibitor that can inhibit ras-dependent cell transformation. L-731735 can be used in cancer research .

L-731735	Farnesyl Transferase	Cancer
L-731735 is a selective FPTase inhibitor that can inhibit ras-dependent cell transformation. L-731735 can be used in cancer research .

HY-151566

Antifungal agent 46	Ras Farnesyl Transferase Fungal	Infection
Antifungal agent 46 (compound 2f) is a potent antifungal agent. Antifungal agent 46 prevents *Ras* signaling by inhibiting protein farnesyltransferase .

HY-119264A

PRLX-93936 dihydrochloride	HIF/HIF Prolyl-Hydroxylase Ras	Cancer
PRLX-93936 dihydrochloride (Compound 16) is a HIF-1α inhibitor with anticancer activity. PRLX-93936 can inhibit the activated *Ras* pathway and can be used in the study of relapsed or refractory multiple myeloma .

HY-136579

ASN007 ERK-IN-3	ERK	Cancer
ASN007 (ERK-IN-3) is a potent and orally active inhibitor of ERK. ASN007 inhibits ERK1/2 with low single-digit nM IC₅₀ values. ASN007 can be used for the research of cancers driven by RAS mutations .

HY-136579A

ASN007 benzenesulfonate ERK-IN-3 benzenesulfonate	ERK	Cancer
ASN007 (ERK-IN-3) benzenesulfonate is a potent and orally active inhibitor of ERK. ASN007 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC₅₀ values. ASN007 benzenesulfonate can be used for the research of cancers driven by RAS mutations .

HY-157740

XSJ-10	HDAC	Cancer
XSJ-10 is a HDAC inhibitor containing a RAS/RAF protein interfering unit, with IC_{50_s} of 0.05 and 0.04 μM in PANC-1 cells and HT-29 cells. XSJ-10 can effectively induce the apoptosis of cancer cells and suppress the tumor by strongly inhibiting the RAS-RAF-MEK-ERK signaling pathway and the acetylation level of HDAC3 .

HY-16059

Arglabin (+)-Arglabin	NOD-like Receptor (NLR) Farnesyl Transferase Autophagy	Inflammation/Immunology Cancer
Arglabin ((+)-Arglabin), a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor. Arglabin shows anti-inflammatory and antitumor activities . The antitumor activity of Arglabin proceeds through its inhibition of farnesyl transferase which leads to the activation of RAS proto-oncogene .

HY-156498

RMC-7977	Ras	Cancer
RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.RMC-7977 can lead to tumor regressions and was well tolerated in diverse RAS-addicted preclinical cancer models. RMC-7977 also can inhibit the growth of KRAS ^G12C cancer models .

HY-156500

ICMT-IN-1	ICMT	Cancer
ICMT-IN-1 (compound 75) is an inhibitor of ICMT (IC₅₀=0.0013 μM). ICMT-IN-1 dose-dependently induces ICMT accumulation in the cytoplasm of HCT-116 cells and inhibits the proliferation of multiple cancer cell lines expressing K-Ras and N-Ras .

HY-149705

ICMT-IN-7	ICMT	Cancer
ICMT-IN-7 (compound 74) is an inhibitor of ICMT (IC₅₀=0.015 μM). ICMT-IN-7 dose-dependently induces ICMT accumulation in the cytoplasm of HCT-116 cells and inhibits the proliferation of multiple cancer cell lines expressing K-Ras and N-Ras .

HY-121532

(-)-Rasfonin	Ras Apoptosis Autophagy	Cancer
(-)-Rasfonin is a fungal secondary metabolite and inhibits small G proteins Ras. (-)-Rasfonin induces apoptosis, necrosis and autophagy in ACHN cells (a renal carcinoma cell line) .

HY-106770

Esuprone	Monoamine Oxidase	Neurological Disease
Esuprone is a brain-penetrant, orally active and selective MAO A inhibitor with an IC₅₀ of 7.3 nM. Esuprone can be used for neurological research .

HY-124944

APS6-45

Ras Cancer

APS6-45 is an orally active tumor-calibrated inhibitor (TCI). APS6-45 inhibits RAS/MAPK signaling and exhibits antitumor activity .

APS6-45	Ras	Cancer
APS6-45 is an orally active tumor-calibrated inhibitor (TCI). APS6-45 inhibits RAS/MAPK signaling and exhibits antitumor activity .

HY-113680

KY1022	Apoptosis Ras β-catenin Wnt	Cancer
KY1022 is a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway. KY1022 can inhibit cellular EMT, metastasis and apoptosis. KY1022 can be used for the research of metastatic colorectal cancer .

HY-111671

SOS1 activator 1	Ras	Cancer
SOS1 activator 1 (Compound 64) is a potent activator of SOS1-mediated nucleotide exchange with a K_d of 44 nM. SOS1 is a guanine nucleotide exchange factor that catalyzes the exchange of GDP for GTP on RAS .

HY-142452

Pan-RAF kinase inhibitor 1	Raf	Cancer
Pan-RAF kinase inhibitor 1 is a potent inhibitor of Pan-RAF kinase. Pan-RAF kinase inhibitor 1 regulates MAPK signaling by inhibiting RAF kinase, thereby exerting an effect on the proliferation of RAS-mutant tumor cells. Pan-RAF kinase inhibitor 1 has the potential for the research of cancer diseases (extracted from patent WO2021110141A1, compound 16B) .

HY-149709

ICMT-IN-35	ICMT	Cancer
ICMT-IN-35 (compound 10n) is a FTPA-triazole compound and ICMT inhibitor (IC₅₀=0.8 μM). ICMT-IN-35 is taken up by mammalian cells and can prevent K-Ras membrane localization and induce K-Ras mislocalization. Furthermore, ICMT-IN-35 is selectively cytotoxic against ICMT ^+/+ MEF cells and has low micromolar activity (IC₅₀=0.8 μM) against metastatic pancreatic cancer cell lines .

Cat. No.	Product Name

HY-L077

Anti-Pancreatic Cancer Compound Library

2,713 compounds

Pancreatic cancer is a devastating disease with a low overall survival rate. Chemotherapy is the most common treatment for patients presenting with advanced pancreatic cancer. More recently, the era of targeted therapies has generated a lot of interest in discovering better approaches for patients with pancreatic cancer. Commonly mutated genes in pancreatic cancer include K-ras (in 74-100% of cases), p16INK4a (up to 98%), p53 (43 to 76%), DPC4 (about 50%), HER-2/neu (in about 65%) and FHIT (found in 70% of cases). Other genes involved are notch1, Akt-2, BRCA2 and COX-2. These proteins are important targets of target therapies for pancreatic cancer.

MCE offers a unique collection of 2,713 compounds with identified and potential anti- pancreatic cancer activity. These compounds target K-Ras, p53, HER2, Notch, AKT, etc. MCE anti-pancreatic cancer compound library is a useful tool for anti-pancreatic cancer drugs screening and other related research.

HY-L145

Antihypertensive Compound Library

487 compounds

The majority of hypertensive patients have primary (or essential) hypertension, that is, hypertension in which secondary causes are not present. Management aims to control arterial pressure, prevent end-organ damage (cerebrovascular, cardiovascular, and renal), and reduce the risk of premature death.

Antihypertensive drugs may be divided into two broad groups, the first group being those which directly or indirectly block the renin–angiotensin system (RAS), for example, ACEIs, angiotensin receptor antagonists (ARAs), direct renin inhibitors (DRIs), and to a lesser extent β-blockers. The second group of drugs works by increasing water and sodium excretion, thereby reducing intravascular volume, or by causing vasodilatation through non-RAS pathways, for example, diuretics and calcium channel blockers (CCBs).

MCE offers a unique collection of 487 compounds with identified and potential antihypertensive activity. MCE Antihypertensive Compound Library is critical for antihypertensive drug discovery and development.

Cat. No.	Product Name	Target	Research Area

HY-P2360

G12 ras 5-17	Peptides	Others
G12 (Ras 5-17) is a wild-type Ras peptide consisted of amino acids 5-17 (KLVVVGAGGVGKS). G12 can be used as a control of mutant Ras peptides studies (such V12) .

HY-P2361

S12

Peptides Others

S12 is a mutant RAS peptide containing the Gly (G) to Ser (S12) substitution. The sequence of the peptide is KLVVVGASGVGKS .

HY-12403A

Talfirastide acetate 5+ Cited Publications TXA127 acetate; Angiotensin (1-7) (acetate); Ang-(1-7) (acetate)	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology
Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .

HY-P2360A

G12 TFA ras 5-17 TFA	Peptides	Others
G12 (Ras 5-17) TFA is a wild-type Ras peptide consisted of amino acids 5-17 (KLVVVGAGGVGKS). G12 TFA can be used as a control of mutant Ras peptides studies (such V12) .

HY-P2157

Ras Inhibitory Peptide

Ras Cancer

Ras Inhibitory Peptide (VPPPVPPRRR) is a Ras inhibitor with antitumor activity .
HY-P3277

KRpep-2d

Ras Cancer

KRpep-2d is a potent K-Ras inhibitor and inhibits proliferation of K-Ras-driven cancer cells. KRpep-2d can be used for cancer research .
HY-P3277A

KRpep-2d TFA

Ras Cancer

KRpep-2d (TFA) is a potent K-Ras inhibitor and inhibits proliferation of K-Ras-driven cancer cells. KRpep-2d can be used for cancer research .
HY-P10051

Cyclorasin 9A5

Ras Raf Cancer

Cyclorasin 9A5 is an 11-residue cell-permeable cyclic peptide that orthosterically inhibits the Ras-Raf protein interaction with an IC₅₀ of 120 nM .

HY-110183

Angiotensin A	Peptides	Cardiovascular Disease
Angiotensin A is a renin–angiotensin system (RAS) peptide that causes a vasoconstrictive effect dependent on AT₁ receptors. Angiotensin A elicits pressor and renal vasoconstrictor responses in normotensive and hypertensive rats .

HY-P3108

Alamandine	Angiotensin Receptor Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Alamandine, a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine targets to protect the kidney and heart through anti-hypertensive actions .

HY-12403

Talfirastide 5+ Cited Publications TXA127; Angiotensin (1-7); Ang-(1-7)	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology
Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-16059

Arglabin (+)-Arglabin	Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Source classification Apios americana Medik. Plants Compositae Inflammation/Immunology Disease Research Fields	NOD-like Receptor (NLR) Farnesyl Transferase Autophagy
Arglabin ((+)-Arglabin), a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor. Arglabin shows anti-inflammatory and antitumor activities . The antitumor activity of Arglabin proceeds through its inhibition of farnesyl transferase which leads to the activation of RAS proto-oncogene .

HY-B0660

Eicosapentaenoic Acid Maximum Cited Publications 11 Publications Verification EPA; Timnodonic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Histone Demethylase
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-W048303

L-Azatyrosine	Infection Structural Classification Microorganisms Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Phenols Disease Research Fields	Antibiotic
L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes .

HY-121532

(-)-Rasfonin	Monophenols Microorganisms Classification of Application Fields Source classification Phenols Disease Research Fields Cancer	Ras Apoptosis Autophagy
(-)-Rasfonin is a fungal secondary metabolite and inhibits small G proteins Ras. (-)-Rasfonin induces apoptosis, necrosis and autophagy in ACHN cells (a renal carcinoma cell line) .

HY-W011269

Eicosapentaenoic Acid sodium EPA sodium; Timnodonic acid sodium	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Histone Demethylase
Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-12403A

Talfirastide acetate 5+ Cited Publications TXA127 acetate; Angiotensin (1-7) (acetate); Ang-(1-7) (acetate)	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Endocrinology	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite
Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .

HY-128553

Antineoplaston A10	Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Ras Apoptosis Endogenous Metabolite
Antineoplaston A10, a naturally occurring substance in human body, is a *Ras* inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer .

HY-N6796

Manumycin A	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Other Antibiotics	Farnesyl Transferase Ras Apoptosis Phospholipase
Manumycin A is an antibiotic. Manumycin A acts as a selective, competitive inhibitor of protein farnesyltransferase (FTase) with respect to farnesylpyrophosphate (K_i=1.2 μM), and as a noncompetitive inhibitor with respect to the *Ras* protein. Manumycin A induces apoptosis and exerts antitumor activity . Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling . Manumycin A is a nSMase inhibitor (EC₅₀=0.25 μM) .

HY-116514

(S)-(−)-Perillyl alcohol	Structural Classification Other Monoterpenes other families Classification of Application Fields Terpenoids Labiatae Source classification Peucephyllum schottii A.Gray Plants Endogenous metabolite Disease Research Fields Cancer	Apoptosis Endogenous Metabolite
(S)-(−)-Perillyl alcohol is a monoterpene found in lavender, inhibits farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis. Anti-cancer activity .

HY-112541

21-Hydroxyoligomycin A	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Ras Antibiotic
21-Hydroxyoligomycin A is a potent inhibitor of *K-Ras* PM localization with an IC₅₀** value of 4.82 nM. 21-Hydroxyoligomycin A has cytotoxicity and can be isolated from Streptomyces .

HY-N1374

Magnolin 1 Publications Verification	Structural Classification Classification of Application Fields Source classification Magnoliaceae Lignans Magnolia Liliflora Desr. Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	ERK
Magnolin, a major component of Magnolia liliiflora, inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC₅₀s of 87 nM and 16.5 nM, respectively.

HY-113313

Aldosterone 5 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .

HY-113313R

Aldosterone (Standard)	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Aldosterone (Standard) is the analytical standard of Aldosterone. This product is intended for research and analytical applications. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .

HY-N10503

Norartocarpetin	Structural Classification Flavonoids Flavones Plants Moraceae	Tyrosinase Ras Raf MAPKAPK2 (MK2) Apoptosis
Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC₅₀ value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC₅₀ value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells .

HY-12403

Talfirastide 5+ Cited Publications TXA127; Angiotensin (1-7); Ang-(1-7)	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite
Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .

Species:	Human (58) Virus (1) Rat (2) Mouse (1)
Tag:	His (53) Tag Free (3) Strep (2) Avi (28) GST (3) Fc (3)
Source:	HEK293 (35) E. coli Cell-free (1) Sf9 insect cells (3) P. pastoris (1) E. coli (22)

Cat. No.	Compare	Product Name	Species	Source

HY-P77783

	*HLA-A1101 KRAS G12D Protein, Human (HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12D Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGADGVGK peptide. HLA-A*1101 KRAS G12D Protein, Human (HEK293, His-Avi), has molecular weight of 51-60 kDa.

HY-P77786

	*HLA-A1101 KRAS G12V Complex Protein, Human (HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12V Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*1101 KRAS G12V Complex Protein, Human (HEK293, His-Avi), has molecular weight of 42-46 kDa.

HY-P77781

	*HLA-A0301 KRAS G12V Complex Protein, Human (HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A01:01 and A03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A0301 KRAS G12V Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*0301 KRAS G12V Complex Protein, Human (HEK293, His-Avi), has molecular weight of 55-60 kDa.

HY-P77785

	*HLA-A1101 KRAS G12D Tetramer Protein, Human (HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12D Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGADGVGK peptide. HLA-A*1101 KRAS G12D Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.

HY-P77790

	*HLA-A0301 KRAS WT Protein, Human (Biotinylated, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A01:01 and A03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A0301 KRAS WT Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*0301 KRAS WT Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 52-62 kDa.

HY-P77789

	*HLA-A0301 KRAS WT Protein, Human (HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A01:01 and A03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A0301 KRAS WT Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*0301 KRAS WT Protein, Human (HEK293, His-Avi), has molecular weight of 52-62 kDa.

HY-P700929

	*HLA-A1101 KRAS WT Complex Protein, Human (Biotinylated, VVVGAGGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS WT Complex Protein, Human (Biotinylated, VVVGAGGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*1101 KRAS WT Complex Protein, Human (Biotinylated, VVVGAGGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.

HY-P700930

	*HLA-A1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi), has molecular weight of 52-62 kDa.

HY-P700931

	*HLA-A1101 KRAS WT Complex Tetramer Protein, Human (VVVGAGGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS WT Complex Tetramer Protein, Human (VVVGAGGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*1101 KRAS WT Complex Tetramer Protein, Human (VVVGAGGVGK, HEK293, His-Avi), has molecular weight of 260-265 kDa.

HY-P77791

	*HLA-A0301 KRAS WT Tetramer Protein, Human (HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A01:01 and A03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A0301 KRAS WT Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-His, C-Avi labeled tag and VVVGAGGVGK peptide. HLA-A*0301 KRAS WT Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.

HY-P701974

	RRAS2 Protein, Human Rras2; ras-related protein R-ras2; ras-like protein TC21; Teratocarcinoma oncogene	Human	E. coli
	RRAS2 protein, a GTP-binding with GTPase activity, crucially regulates the MAPK signaling pathway, impacting diverse cellular processes and playing a pivotal role in orchestrating cellular responses. Its influence extends to regulating craniofacial development, emphasizing its multifaceted role in biological pathways essential for proper cellular and developmental outcomes. RRAS2 Protein, Human is the recombinant human-derived RRAS2 protein, expressed by E. coli , with tag free. The total length of RRAS2 Protein, Human is 204 a.a., .

HY-P77782

	*HLA-A0301 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A01:01 and A03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A0301 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*0301 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.

HY-P77784

	*HLA-A1101 KRAS G12D Complex Protein, Human (Biotinylated, VVVGADGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12D Complex Protein, Human (Biotinylated, VVVGADGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGADGVGK peptide. HLA-A*1101 KRAS G12D Complex Protein, Human (Biotinylated, VVVGADGVGK, HEK293, His-Avi), has molecular weight of 51-60 kDa.

HY-P77787

	*HLA-A1101 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*1101 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi), has molecular weight of 51-60 kDa.

HY-P77788

	*HLA-A1101 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*1101 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.

HY-P700919

	*HLA-A1101 KRAS G12A Complex Protein, Human (Biotinylated, VVVGAAGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12A Complex Protein, Human (Biotinylated, VVVGAAGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAAGVGK peptide. HLA-A*1101 KRAS G12A Complex Protein, Human (Biotinylated, VVVGAAGVGK, HEK293, His-Avi), has molecular weight of 52-62 kDa.

HY-P700920

	*HLA-A1101 KRAS G12A Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12A Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAAGVGK peptide. HLA-A*1101 KRAS G12A Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi), has molecular weight of 52-62 kDa.

HY-P700921

	*HLA-A1101 KRAS G12C Complex Protein, Human (Biotinylated, VVVGACGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12C Complex Protein, Human (Biotinylated, VVVGACGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGACGVGK peptide. HLA-A*1101 KRAS G12C Complex Protein, Human (Biotinylated, VVVGACGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.

HY-P700922

	*HLA-A1101 KRAS G12C Complex Protein, Human (VVVGACGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12C Complex Protein, Human (VVVGACGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGACGVGK peptide. HLA-A*1101 KRAS G12C Complex Protein, Human (VVVGACGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.

HY-P700923

	*HLA-A1101 KRAS G12R Complex Protein, Human (Biotinylated, VVVGARGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12R Complex Protein, Human (Biotinylated, VVVGARGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGARGVGK peptide. HLA-A*1101 KRAS G12R Complex Protein, Human (Biotinylated, VVVGARGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.

HY-P700924

	*HLA-A1101 KRAS G12R Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12R Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGARGVGK peptide. HLA-A*1101 KRAS G12R Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.

HY-P700925

	*HLA-A1101 KRAS G12S Complex Protein, Human (Biotinylated, VVVGASGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12S Complex Protein, Human (Biotinylated, VVVGASGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGASGVGK peptide. HLA-A*1101 KRAS G12S Complex Protein, Human (Biotinylated, VVVGASGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.

HY-P700926

	*HLA-A1101 KRAS G12S Complex Protein, Human (VVVGASGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A1101 KRAS G12S Complex Protein, Human (VVVGASGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGASGVGK peptide. HLA-A*1101 KRAS G12S Complex Protein, Human (VVVGASGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.

HY-P700927

	*HLA-A0301 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A01:01 and A03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A0301 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*0301 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi), has molecular weight of 52-60 kDa.

HY-P700928

	*HLA-A0301 KRAS G12V Complex Protein, Human (VVGAVGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A0301 KRAS G12V Complex Protein, Human (VVGAVGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*0301 KRAS G12V Complex Protein, Human (VVGAVGVGK, HEK293, His-Avi), has molecular weight of 56-65 kDa.

HY-P701086

	*HLA-C0304 KRAS G12D Complex Protein, Human (Biotinylated, GADGVGKSAL, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	The HLA-C0304 KRAS G12D Complex, a major histocompatibility complex class I (MHCI) molecule, plays crucial roles in reproduction and antiviral immunity. Teaming up with B2M, it presents self and viral peptides, acting as a dominant ligand for inhibitory and activating killer immunoglobulin receptors (KIRs) on NK cells. In allogeneic contexts, it facilitates trophoblast interactions with NK cells, crucial for placental development. During viral infections, HLA-C0304 may disrupt KIR-mediated inhibition and promote infected cell lysis. In adaptive immunity, it presents viral peptides to CD8-positive T cells, contributing to antigen-specific T cell responses in chronic viral infections. HLA-C0304's fine specificity for antigen recognition and its role in immune surveillance stem from its ability to recognize diverse peptides and specific MHC residues. HLA-C0304 KRAS G12D Complex Protein, Human (Biotinylated, GADGVGKSAL, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-C0304 and B2M/Beta-2-microglobulin Protein, expressed by HEK293* , with C-Avi, C-His labeled tag and GADGVGKSAL peptide. HLA-C*0304 KRAS G12D Complex Protein, Human (Biotinylated, GADGVGKSAL, HEK293, His-Avi), has molecular weight of 55-65 kDa.

HY-P701087

	*HLA-C0304 KRAS G12D Complex Protein, Human (GADGVGKSAL, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	The HLA-C0304 KRAS G12D Complex, a major histocompatibility complex class I (MHCI) molecule, plays crucial roles in reproduction and antiviral immunity. Teaming up with B2M, it presents self and viral peptides, acting as a dominant ligand for inhibitory and activating killer immunoglobulin receptors (KIRs) on NK cells. In allogeneic contexts, it facilitates trophoblast interactions with NK cells, crucial for placental development. During viral infections, HLA-C0304 may disrupt KIR-mediated inhibition and promote infected cell lysis. In adaptive immunity, it presents viral peptides to CD8-positive T cells, contributing to antigen-specific T cell responses in chronic viral infections. HLA-C0304's fine specificity for antigen recognition and its role in immune surveillance stem from its ability to recognize diverse peptides and specific MHC residues. HLA-C0304 KRAS G12D Complex Protein, Human (GADGVGKSAL, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-C0304 and B2M/Beta-2-microglobulin Protein, expressed by HEK293* , with C-Avi, C-His labeled tag and GADGVGKSAL peptide. HLA-C*0304 KRAS G12D Complex Protein, Human (GADGVGKSAL, HEK293, His-Avi), has molecular weight of 55-65 kDa.

HY-P701088

	*HLA-C0304 KRAS G12D Complex Tetramer Protein, Human (GADGVGKSAL, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	The HLA-C0304 KRAS G12D Complex, a major histocompatibility complex class I (MHCI) molecule, plays crucial roles in reproduction and antiviral immunity. Teaming up with B2M, it presents self and viral peptides, acting as a dominant ligand for inhibitory and activating killer immunoglobulin receptors (KIRs) on NK cells. In allogeneic contexts, it facilitates trophoblast interactions with NK cells, crucial for placental development. During viral infections, HLA-C0304 may disrupt KIR-mediated inhibition and promote infected cell lysis. In adaptive immunity, it presents viral peptides to CD8-positive T cells, contributing to antigen-specific T cell responses in chronic viral infections. HLA-C0304's fine specificity for antigen recognition and its role in immune surveillance stem from its ability to recognize diverse peptides and specific MHC residues. HLA-C0304 KRAS G12D Complex Tetramer Protein, Human (GADGVGKSAL, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-C0304 and B2M/Beta-2-microglobulin Protein, expressed by HEK293* , with C-Avi, C-His labeled tag and GADGVGKSAL peptide. HLA-C*0304 KRAS G12D Complex Tetramer Protein, Human (GADGVGKSAL, HEK293, His-Avi), has molecular weight of 260-265 kDa.

HY-P701089

	*FITC labeled HLA-A1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi)** MHC; Kras; K-ras 2; Kras2; C-K-ras; CFC2; K-ras2A; K-ras2B; K-ras4A; K-ras4B; Kras1; Kras2; NS; NS3; rasK2; GTPase Kras; KI-ras; RALD	Human	HEK293
	HLA-A1101as is a key MHCI molecule that presents viral and tumor-derived peptides that direct T cell immune responses against infected or transformed cells. It collaborates with B2M to showcase a diverse peptide library. FITC labeled HLA-A1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293* , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. FITC labeled HLA-A*1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi), has molecular weight of 55-60 kDa.

HY-P701975

	RRAS2 Protein, Human (His, Strep) Rras2; ras-related protein R-ras2; ras-like protein TC21; Teratocarcinoma oncogene	Human	E. coli
	RRAS2 protein, a GTP-binding with GTPase activity, crucially regulates the MAPK signaling pathway, impacting diverse cellular processes and playing a pivotal role in orchestrating cellular responses. Its influence extends to regulating craniofacial development, emphasizing its multifaceted role in biological pathways essential for proper cellular and developmental outcomes. RRAS2 Protein, Human (His, Strep) is the recombinant human-derived RRAS2 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of RRAS2 Protein, Human (His, Strep) is 204 a.a., .

HY-P75998

	RAB7A Protein, Rat (His) ras-related protein Rab-7a; ras-related protein BRL-ras; RAB7A; RAB7	Rat	E. coli
	RAB7A is a dynamic small GTPase that coordinates endolysosomal trafficking by cycling between a GTP-bound state and a GDP-bound state. In its active state, RAB7A interacts with various effectors, affecting endosomal maturation, microtubule directed migration, and endosome-lysosomal trafficking. RAB7A Protein, Rat (His) is the recombinant rat-derived RAB7A protein, expressed by E. coli , with N-His labeled tag. The total length of RAB7A Protein, Rat (His) is 207 a.a., with molecular weight of ~25.7 kDa.

HY-P75998A

RAB7A Protein, Rat (N-His)

ras-related protein Rab-7a; ras-related protein BRL-ras; RAB7A; RAB7
Rat E. coli

HY-P7804

	KRAS Protein, Human (G12C, His) Ki-ras; c-K-ras; Kras2; rasK2	Human	E. coli
	KRAS Protein, Human (G12C, His) expresses in E. coli with a His tag at the N-terminus. KRAS G12C is an oncogenic driver mutation in multiple cancer types.

HY-P7805A

	KRAS Protein, Human (G13V, His) Ki-ras; c-K-ras; Kras2; rasK2	Human	E. coli
	KRAS Protein, a pivotal Ras family member, binds GDP/GTP and possesses intrinsic GTPase activity. Its crucial role in regulating cell proliferation emphasizes its significance in cellular processes. Notably, KRAS plays a prominent role in promoting oncogenic events, particularly in colorectal cancer (CRC), inducing transcriptional silencing of tumor suppressor genes (TSGs) in a ZNF304-dependent manner. This multifaceted functionality underscores KRAS as a key player in cellular dynamics, relevant in both normal and pathological processes. KRAS Protein, Human (G13V, His) is the recombinant human-derived KRAS protein, expressed by E. coli , with N-6*His labeled tag and G13V mutation. The total length of KRAS Protein, Human (G13V, His) is 184 a.a., with molecular weight of ~25 kDa.

HY-P7804A

	KRAS Protein, Human (G13C, His) Ki-ras; c-K-ras; Kras2; rasK2	Human	E. coli
	KRAS protein is a key Ras family member that binds GDP/GTP and has intrinsic GTPase activity. Its critical role in regulating cell proliferation emphasizes its importance in cellular processes. KRAS Protein, Human (G13C, His) is the recombinant human-derived KRAS protein, expressed by E. coli , with N-6*His labeled tag and G13C, , , , mutation. The total length of KRAS Protein, Human (G13C, His) is 184 a.a., with molecular weight of ~25 kDa.

HY-P7805

	KRAS Protein, Human (G12V, His) Ki-ras; c-K-ras; Kras2; rasK2; Kras4B; Kras4B; K-ras4B	Human	E. coli
	KRAS Protein, a pivotal Ras family member, binds GDP/GTP and possesses intrinsic GTPase activity. Its crucial role in regulating cell proliferation emphasizes its significance in cellular processes. Notably, KRAS plays a prominent role in promoting oncogenic events, particularly in colorectal cancer (CRC), inducing transcriptional silencing of tumor suppressor genes (TSGs) in a ZNF304-dependent manner. This multifaceted functionality underscores KRAS as a key player in cellular dynamics, relevant in both normal and pathological processes. KRAS Protein, Human (G12V, His) is the recombinant human-derived KRAS protein, expressed by E. coli , with N-6*His labeled tag and G12V mutation. The total length of KRAS Protein, Human (G12V, His) is 184 a.a., with molecular weight of 25-30 kDa, observed by reducing SDS-PAGE.

HY-P76561

	RAB31 Protein, Human (His) ras-related protein Rab-31; ras-related protein Rab-22B; RAB31; RAB22B	Human	E. coli
	RAB31 protein binds GDP and GTP and participates in processes like protein transport, insulin response, and receptor internalization. It is mainly located in the early endosome, phagocytic vesicle, and trans-Golgi network membrane. RAB31 is also a biomarker for severe acute respiratory syndrome and is broadly expressed in tissues such as the brain, adrenal glands, and 22 others. RAB31 Protein, Human (His) is the recombinant human-derived RAB31 protein, expressed by E. coli , with N-His labeled tag. The total length of RAB31 Protein, Human (His) is 195 a.a., with molecular weight of ~26 kDa.

HY-P70233

	Kras4B Protein, Human (His) rHuGTPase Kras4B, His; Ki-ras; c-K-ras; Kras2; rasK2; CFC2	Human	E. coli
	The Kras4B protein interacts specifically with GPR31, dependent on farnesylation. This binding suggests a regulatory role for Kras4B in association with GPR31, emphasizing the importance of the farnesylation process. Comprehensive exploration into the molecular details of this interaction is crucial to understand the precise mechanisms and functional implications in cellular processes or signaling pathways. Kras4B Protein, Human (His) is the recombinant human-derived Kras4B protein, expressed by E. coli , with N-6*His labeled tag. The total length of Kras4B Protein, Human (His) is 150 a.a., with molecular weight of ~23.0 kDa.

HY-P70153

KRAS Protein, Human (G12S, His)

rHuKras-G12S, His; Ki-ras; c-K-ras; Kras2; rasK2; CFC2
Human E. coli

HY-P76838

	CNKSR3 Protein, Human (sf9, GST) Connector enhancer of kinase suppressor of ras 3; CNK3; Maguin-like protein; MAGI1	Human	Sf9 insect cells
	CNKSR3 protein regulates transepithelial sodium transport by controlling aldosterone-induced ENaC-mediated sodium transport. As a scaffolding protein, CNKSR3 coordinates ENaC regulatory complex (ERC) assembly and directly interacts with ENaC subunits SCNN1A and SCNN1B. CNKSR3 Protein, Human (sf9, GST) is the recombinant human-derived CNKSR3 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of CNKSR3 Protein, Human (sf9, GST) is 352 a.a., with molecular weight of 53-65 kDa.

HY-P71619

	SYNGAP1 Protein, Human (His) DKFZp761G1421 ; KIAA1938; MRD5; Neuronal rasGAP; OTTHUMP00000064825; p135 SynGAP; ras GTPase activating protein SynGAP; Synaptic ras-GAP 1; SYNGAP 1; SYNGAP1	Human	E. coli
	SYNGAP1 protein is a major postsynaptic density component that plays a critical regulatory role in the Ras-cAMP pathway, affecting synaptic function and plasticity. At excitatory synapses, it is part of the NMDAR signaling complex and may influence NMDAR-dependent control of AMPAR potentiation, trafficking, and synaptic plasticity. SYNGAP1 Protein, Human (His) is the recombinant human-derived SYNGAP1 protein, expressed by E. coli , with N-His labeled tag. The total length of SYNGAP1 Protein, Human (His) is 183 a.a., with molecular weight of ~25.5 kDa.

HY-P70232

	Kras4B Protein, Human (G12C, His) rHuGTPase Kras4B-G12C, His; Ki-ras; c-K-ras; Kras2; rasK2; CFC2	Human	E. coli
	The Kras4B protein interacts specifically with GPR31, dependent on farnesylation. This binding suggests a regulatory role for Kras4B in association with GPR31, emphasizing the importance of the farnesylation process. Comprehensive exploration into the molecular details of this interaction is crucial to understand the precise mechanisms and functional implications in cellular processes or signaling pathways. Kras4B Protein, Human (G12C, His) is the recombinant human-derived Kras4B protein, expressed by E. coli , with N-6*His labeled tag and G12C, , , , mutation. The total length of Kras4B Protein, Human (G12C, His) is 169 a.a., with molecular weight of ~23.0 kDa.

HY-P70234

	Kras4B Protein, Human (G12V, His) rHuGTPase Kras4B-G12V, His; Ki-ras; c-K-ras; Kras2; rasK2; CFC2	Human	E. coli
	The Kras4B protein interacts specifically with GPR31, dependent on farnesylation. This binding suggests a regulatory role for Kras4B in association with GPR31, emphasizing the importance of the farnesylation process. Comprehensive exploration into the molecular details of this interaction is crucial to understand the precise mechanisms and functional implications in cellular processes or signaling pathways. Kras4B Protein, Human (G12V, His) is the recombinant human-derived Kras4B protein, expressed by E. coli , with N-6*His labeled tag. The total length of Kras4B Protein, Human (G12V, His) is 150 a.a., with molecular weight of ~24.0 kDa.

HY-P73919

	HRAS Protein, Human (sf9, His) GTPase Hras; Ha-ras; Hras; Hras1	Human	Sf9 insect cells
	HRAS Protein, a key player in initiating Ras protein signal transduction, facilitates the activation of Ras signaling cascades at the molecular level. Under HRAS influence, Ras proteins exhibit GDP/GTP binding and intrinsic GTPase activity, as confirmed by studies. These interactions underscore HRAS's integral role in orchestrating signal transduction dynamics, emphasizing its significance in cellular communication and regulation. HRAS Protein, Human (sf9, His) is the recombinant human-derived HRAS protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of HRAS Protein, Human (sf9, His) is 186 a.a., with molecular weight of ~23 kDa.

HY-P73769

	*NA/Neuraminidase Protein, H3N2 (ADT79152, HEK293, His)* NA; Neuraminidase; NA/Neuraminidase Protein, H3N2 (A/swine/Italy/526/1985, HEK293, His)	Virus	HEK293
	NA/Neuraminidase Protein is a receptor-destroying enzyme that cleaves terminal sialic acids from cellular receptors, potentially facilitating viral invasion of the upper airways by targeting sialic acid moieties on airway epithelial cell mucin. NA plays a pivotal role in viral propagation by catalyzing the removal of terminal sialic acid residues from both viral and cellular glycoconjugates. Moreover, the sialidase activity in late endosome/lysosome traffic appears to enhance virus replication. NA/Neuraminidase Protein, H3N2 (ADT79152, HEK293, His) is the recombinant Virus-derived NA/Neuraminidase protein, expressed by HEK293 , with N-His labeled tag. The total length of NA/Neuraminidase Protein, H3N2 (ADT79152, HEK293, His) is 434 a.a., with molecular weight of ~50.7 kDa.

HY-P73741

	NRAS Protein, Human (His, solution) GTPase Nras; Transforming protein N-ras; Nras; Hras1	Human	E. coli
	NRAS protein is a member of the Ras family that binds GDP/GTP and has intrinsic GTPase activity. This property enables NRAS to actively regulate cellular processes by cycling between a GDP-bound inactive state and a GTP-bound active state. NRAS Protein, Human (His, solution) is the recombinant human-derived NRAS protein, expressed by E. coli , with N-His labeled tag. The total length of NRAS Protein, Human (His, solution) is 186 a.a., with molecular weight of ~24 kDa.

HY-P73741A

	NRAS Protein, Human (N-His) GTPase Nras; Transforming protein N-ras; Nras; Hras1	Human	E. coli
	NRAS protein is a member of the Ras family that binds GDP/GTP and has intrinsic GTPase activity. This property enables NRAS to actively regulate cellular processes by cycling between a GDP-bound inactive state and a GTP-bound active state. NRAS Protein, Human (N-His) is the recombinant human-derived NRAS protein, expressed by E. coli , with N-His labeled tag. The total length of NRAS Protein, Human (N-His) is 186 a.a., with molecular weight of ~23 kDa.

HY-P71260

	RHEB Protein, Human (GST) GTP-Binding Protein Rheb; ras Homolog Enriched in Brain; RHEB; RHEB2	Human	E. coli
	RHEB is an important small GTPase that acts as an allosteric activator of the mTORC1 complex, a key nutrient sensor that controls cell growth and biomass production. In response to signals such as nutrients and growth factors, RHEB activates the MTOR kinase within mTORC1 by inducing conformational changes. RHEB Protein, Human (GST) is the recombinant human-derived RHEB protein, expressed by E. coli , with N-GST labeled tag. The total length of RHEB Protein, Human (GST) is 184 a.a., with molecular weight of ~45.0 kDa.

HY-P74609

RAB2 Protein, Mouse (His)

ras-related protein Rab-2A; Rab2A; Rab2
Mouse E. coli

HY-P75993

	RAB1B Protein, Human (HEK293, Fc) ras-related protein Rab-1B; RAB1B	Human	HEK293
	The RAB1B protein is an important small GTPase that regulates intracellular membrane trafficking by coordinating vesicular processes through cycling between GDP and GTP forms. It recruits downstream effectors to achieve vesicle functions, including formation, movement, and fusion. RAB1B Protein, Human (HEK293, Fc) is the recombinant human-derived RAB1B protein, expressed by HEK293 , with N-hFc labeled tag. The total length of RAB1B Protein, Human (HEK293, Fc) is 199 a.a., with molecular weight of ~58 kDa.

Cat. No.	Product Name	Chemical Structure

HY-113313S1

Aldosterone-d7

Aldosterone-d₇ is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level[1][2].

HY-113313S2

Aldosterone-d4
Aldosterone-d₄ is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by t

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80298

	Ras Antibody	WB, ICC/IF, IP	Human, Rat
	Ras Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 21 kDa, targeting to Ras. It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Rat.

HY-P83335

MRAS Antibody (YA3080)

NS11; M-ras; Rras3; R-ras3
WB, IP Human, Mouse, Rat
HY-P82071

RALB Antibody (YA1816)

ras-related protein Ral-B
WB, IP Human, Mouse
HY-P82047

Rab45 Antibody (YA1792)

ras-related protein Rab-45
WB, ICC/IF Human, Mouse

HY-P83231

	Rab11A Antibody (YA2976) MGC1490; Rab 11; Rab 11A; Rab-11; RAB11 A; RAB11; Rab11a; RAB11A member ras oncogene family; ras related protein Rab 11A; ras related protein Rab11A; ras-related protein Rab-11A; RB11A; YL 8; YL8	WB, IP	Human, Mouse, Rat

HY-P82046

Rab22A Antibody (YA1791)

ras-related protein Rab-22A
WB, IP Human, Mouse, Rat
HY-P83277

IQGAP2 Antibody (YA3022)

ras GTPase-activating-like protein IQGAP2
WB, IHC-P Human
HY-P82085

GTPase NRAS Antibody (YA1830)

NS6; CMNS; NCMS; ALPS4; N-ras; Nras1
WB, IP Human, Mouse, Rat
HY-P82088

GTPase HRAS Antibody (YA1833)

NS6; CMNS; NCMS; ALPS4; N-ras; Nras1
WB, ICC/IF, IP Human, Mouse, Rat

HY-P82076

	Ran Antibody (YA1821) RAN; ARA24; OK/SW-cl.81; GTP-binding nuclear protein Ran; Androgen receptor-associated protein 24; GTPase Ran; ras-like protein TC4; ras-related nuclear protein	WB, ICC/IF, IP	Human, Mouse, Monkey

HY-P82055

Rab9 Antibody (YA1800)

RAB9A; DmRab9; ras related protein Rab 9A
WB, IHC-P Human, Mouse
HY-P82079

RAP1 Antibody (YA1824)

ras-related protein Rap-1b; K-REV; RAL1B
WB, IP Human, Mouse, Rat
HY-P82136

Rab25 Antibody (YA1881)

RAB25; CATX8; ras-related protein Rab-25; CATX-8
WB Human
HY-P82643

IQGAP1 Antibody (YA2388)

IQGAP1; KIAA0051; ras GTPase-activating-like protein IQGAP1; p195
WB, IHC-P, ICC/IF, FC Human, Mouse
HY-P83099

FNTB Antibody (YA2844)

FNTB; Protein farnesyltransferase subunit beta; FTase-beta; CAAX farnesyltransferase subunit beta; ras proteins prenyltransferase subunit beta
WB, IP Human
HY-P82527

Rab4 Antibody (YA2272)

Rab4; RAB4A; HRES 1; RAB4; ras related protein Rab 4A
WB, ICC/IF, FC Human, Mouse, Rat
HY-P82705

CDC25 Antibody (YA2450)

GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1
WB Rat
HY-P82057

Rac3 Antibody (YA1802)

ras-related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac3)
WB, IHC-P Human, Mouse, Rat
HY-P82859

Phospho-Rac1/CDC42 (Ser71) Antibody (YA2604)

CDC42; CDC42Hs; G25K; TKS; MIG5; ras like protein TC25
WB Human

HY-P82687

	G3BP Antibody (YA2432) G3BP1; G3BP; ras GTPase-activating protein-binding protein 1; G3BP-1; ATP-dependent DNA helicase VIII; hDH VIII; GAP SH3 domain-binding protein 1	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat

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