17 Results for "

Amantadine hydrochloride

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "Amantadine hydrochloride" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-B0402A
CAS No.: 665-66-7
Synonyms: 1-Adamantanamine hydrochloride; 1-Adamantylamine hydrochloride; 1-Aminoadamantane hydrochloride
Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine hydrochloride inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine hydrochloride also has anti-orthopoxvirus and anticancer activity. Amantadine hydrochloride can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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11
11 Publications Verification
Cat. No.: HY-B0402
CAS No.: 768-94-5
Synonyms: 1-Adamantanamine; 1-Aminoadamantane
Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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1
1 Cited Publications
Cat. No.: HY-U00124B
CAS No.: 41544-24-5
Target:  

HSV

Research Areas:  

Infection

Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication .
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Cat. No.: HY-B0402S1
CAS No.: 1219805-53-4
Synonyms: 1-Adamantanamine-d6; 1-Aminoadamantane-d6
Amantadine-d6 is the deuterium labeled Amantadine . Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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Cat. No.: HY-B0402S
CAS No.: 33830-10-3
Synonyms: 1-Adamantanamine-d15; 1-Aminoadamantane-d15
Amantadine-d15 is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent .
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Cat. No.: HY-B0402B
CAS No.: 31377-23-8
Synonyms: 1-Adamantanamine sulfate; 1-Aminoadamantane sulfate
Amantadine (1-Adamantanamine) sulfate is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine sulfate inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine sulfate also has anti-orthopoxvirus and anticancer activity. Amantadine sulfate can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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Cat. No.: HY-B0402AR
CAS No.: 665-66-7
Synonyms: 1-Adamantanamine hydrochloride (Standard); 1-Adamantylamine hydrochloride (Standard); 1-Aminoadamantane hydrochloride (Standard)
Amantadine (hydrochloride) (Standard) is the analytical standard of Amantadine (hydrochloride). This product is intended for research and analytical applications. Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine hydrochloride inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine hydrochloride also has anti-orthopoxvirus and anticancer activity. Amantadine hydrochloride can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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Cat. No.: HY-B0402R1
CAS No.: 768-94-5
Synonyms: 1-Adamantanamine in Methanol (Standard); 1-Aminoadamantane in Methanol (Standard)
Amantadine in Methanol (Standard) is the solution of Amantadine (Standard). This product is intended for research and analytical applications. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research [4] .
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Cat. No.: HY-138573
CAS No.: 880-52-4
Synonyms: 1-Acetamidoadamantane
Target:  

Drug Metabolite

Research Areas:  

Infection Neurological Disease Cancer

N-Acetyl Adamantamine (1-Acetamidoadamantane) is a major metabolite of Amantadine (HY-B0402) [1] .
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Cat. No.: HY-U00124
CAS No.: 53783-83-8
Target:  

HSV

Research Areas:  

Infection

Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication .
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Cat. No.: HY-B0402R
CAS No.: 768-94-5
Synonyms: 1-Adamantanamine (Standard); 1-Aminoadamantane (Standard)
Amantadine (Standard) is the analytical standard of Amantadine. This product is intended for research and analytical applications. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research [4] .
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Cat. No.: HY-W653905
Synonyms: 1-Adamantanamine hydrochloride-d15
Amantadine-d15 hydrochloride is deuterated labeled Amantadine. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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Cat. No.: HY-122261
CAS No.: 34522-38-8
Synonyms: DU-34569 maleate
Target:  

Influenza Virus

Research Areas:  

Infection

Spiroamantadine (DU-34569 maleate) is a compound related to Amantadine (HY-B0402) with anti-influenza virus activity .
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Cat. No.: HY-W210476
CAS No.: 79594-24-4
Target:  

SARS-CoV

Research Areas:  

Infection

Somantadine, an adamantane derivative, is an antiviral agent with high cross-reactivity with anti-amantadine monoclonal antibodies. Somantadine can be used for research of coronavirus-related diseases .
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Cat. No.: HY-155466
CAS No.: 3056144-84-1
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Boc-MIF-1-Am (compound 2) is a human dopamine D2 receptor enhancer (EC50=17.82 nM) and is a bioconjugate of melanostatin (MIF-1) and amantadine. Boc-MIF-1-Am (200 μM) exhibited mild neurotoxicity in SH-SY5Y cells .
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Cat. No.: HY-181885
CAS No.: 3110745-57-5
Research Areas:  

Infection

Antiviral agent 80 is a conjugate of Zanamivir (HY-13210) and Amantadine (HY-13317), acting as a dual inhibitor of influenza virus M2 ion channel/neuraminidase (NA). Antiviral agent 80 exhibits potent inhibitory activity against both wild-type and drug-resistant influenza neuraminidase mutants, with an IC50 value range of 1.50 nM to 120.4 nM. Antiviral agent 80 can be used in influenza-related research .
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Cat. No.: HY-187087
CAS No.: 1231-74-9
Target:  

Influenza Virus

Research Areas:  

Infection

Methyl O-methylpodocarpate is an influenza A virus (H1N1) inhibitor with activity against H1N1 strains resistant to Oseltamivir and Amantadine, with an EC50 of 0.73 μM. Methyl O-methylpodocarpate blocks viral membrane fusion by targeting hemagglutinin (HA). Methyl O-methylpodocarpate shows only weak activity against the H3N2 subtype and exhibits no significant cytotoxicity to MDCK cells. Methyl O-methylpodocarpate can be used in studies related to H1N1 infection .
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