5 Results for "

ApDC

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "ApDC" in MCE Product Catalog:

154
154 Cited Publications
Cat. No.: HY-18738
CAS No.: 5108-96-3
Synonyms: Ammonium pyrrolidinedithiocarbamate; PDTC ammonium; ApDC
Target:  

NF-κB

Research Areas:  

Inflammation/Immunology Cancer

Pyrrolidinedithiocarbamate ammonium (Ammonium pyrrolidinedithiocarbamate) is a selective and blood-brain barrier (BBB) permeable NF-κB inhibitor.
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Cat. No.: HY-102091
CAS No.: 169209-63-6
Synonyms: (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid
Target:  

mGluR

Research Areas:  

Neurological Disease

(2R,4R)-APDC is a group II metabotropic glutamate receptor (mGluR) agonist. (2R,4R)-APDC affects cell proliferation by inhibiting glutamate release, enhancing motor responses produced by D1 receptor activation, or reducing brain-derived neurotrophic factor (BDNF) levels. (2R,4R)-APDC can be used in the study of epilepsy and other neurological diseases .
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Sgc8c-M
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Sgc8c-M
Cat. No.: HY-177571
Synonyms: Sgc8c-VcMMAE
Sgc8c-M is a PTK7-targeted aptamer-drug conjugate (ApDC). Sgc8c-M is composed of the classic PTK7-specific aptamer Sgc8c, a cathepsin B (CTSB)-cleavable valine-citrulline (VC)-based linker, and the potent antimitotic agent Monomethyl auristatin E (MMAE) (HY-15162) as the payload. Sgc8c-M inhibits the growth of PTK7-overexpressing cancer cells. Sgc8c-M can be used for the study of PTK7-expressing advanced solid tumors .
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Cat. No.: HY-169835
CAS No.: 171336-76-8
Target:  

mGluR

Research Areas:  

Neurological Disease

1-Benzyl-APDC acts as an agonist for mGluR6, with an EC50 of 20 μM in CHO cells. 1-Benzyl-APDC is a weak antagonist of mGluR2, with an IC50 of 200 μM .
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Cat. No.: HY-102091A
Purity:  ≥98.0%
Synonyms: (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid hydrate
Target:  

mGluR

Research Areas:  

Neurological Disease

(2R,4R)-APDC hydrate ((2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid hydrate) is a group II metabotropic glutamate receptor (mGluR) agonist. (2R,4R)-APDC hydrate affects cell proliferation by inhibiting glutamate release, enhancing motor responses produced by D1 receptor activation, or reducing brain-derived neurotrophic factor (BDNF) levels. (2R,4R)-APDC hydrate can be used in the study of epilepsy and other neurological diseases .
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