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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Atox1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Atox1" in MCE Product Catalog:
6
6 Cited Publications
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance [1].
Cat. No.: HY-RS01170
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ATOX1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATOX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18509
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Atox1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atox1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184970
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ATOX1 ligand-1 is a copper ion transporter (denoted as Atox1) and can be used for the synthesis of PROTACs, such as DA-PROTAC (HY-147373) [1].
Cat. No.: HY-RS24991
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Atox1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Atox1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-147373
CAS No.: 2488660-12-2
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DA-PROTAC is a potent PROTAC degrader of copper ion-transport proteins Atox1 and CCS. DA-PROTAC can bind both Atox1 and CCS proteins, and the complex can be bound to E3 ligase, leading to increased levels of ubiquitination of Atox1 and CCS and degradation of Atox1 and CCS proteins via the proteasome pathway. DA-PROTAC can be used for triple negative breast cancer research [1].
Cat. No.: HY-181975
CAS No.: 956181-19-4
ATOX1-IN-1 is an inhibitor of ATOX1 (a copper chaperone protein) with a Kd value of 12.5 μM. ATOX1-IN-1 induces intracellular copper accumulation, increases the level of DNA methylation in the NOTCH1 promoter region, and inhibits the NOTCH1/HES1 signaling pathway. ATOX1-IN-1 enhances the sensitivity of hepatocellular carcinoma cells to Cisplatin (HY-17394). ATOX1-IN-1 can be used in hepatocellular carcinoma-related research [1].
Cat. No.: HY-107636R
CAS No.: 497061-48-0
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DC_AC50 (Standard) is the analytical standard of DC_AC50 (HY-107636). This product is intended for research and analytical applications. DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance [1].
Cat. No.: HY-P86777
Synonyms: Atox1 antibody; Atox1_HUMAN antibody; ATX1 antibody; ATX1 antioxidant protein 1 homolog (yeast) antibody; ATX1 antioxidant protein 1 homolog antibody; Copper transport protein antibody; Copper transport protein Atox1 antibody; HAH1 antibody; Metal transport protein antibody; Metal transport protein ATX1 antibody; Atox1 antibody; Atox1_HUMAN antibody; ATX1 antibody; ATX1 antioxidant protein 1 homolog (yeast) antibody; ATX1 antioxidant protein 1 homolog antibody; Copper transport protein antibody; Copper transport protein Atox1 antibody; HAH1 antibody; Metal transport protein antibody; Metal transport protein ATX1 antibody; MGC138453 antibody; MGC138455 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
