11 Results for "

BMP9

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "BMP9" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99353
CAS No.: 1463459-96-2
Synonyms: Anti-ACVRL1 / ALK-1 Reference Antibody (ascrinvacumab); PF-03446962; GT-90001C

Research Areas:  

Cancer

Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a Kd value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC) .
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2
2 Cited Publications
Cat. No.: HY-P700530
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GDF-2; BMP-9; GDF2; BMP9
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1
1 Cited Publications
Cat. No.: HY-P99590A
Synonyms: RAP-011
Sotatercept (mIgG2a) (RAP-011), the murine homolog of Sotatercept (ACE-011) (HY-P99590), is a soluble activin receptor type IIA (ActRIIA) ligand trap. Sotatercept (mIgG2a) inhibits the binding of activin A and other members of the TGF-β superfamily (such as Activin A/B, GDF11 and BMP9/10) to their receptors by combining and neutralizing them, thereby regulating cell proliferation and differentiation. Sotatercept (mIgG2a) mainly inhibits the SMAD2/3 signaling pathway, and can be used in various diseases such as chronic kidney disease. Sotatercept (mIgG2a) reduces the expression of erythropoietic hepcidin (ERFE), regulates iron metabolism, and promotes red blood cell production. Sotatercept (mIgG2a) has a dual effect of promoting bone formation (anabolic) and inhibiting bone resorption (catabolic) .
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1
1 Cited Publications
Cat. No.: HY-P700033AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GDF-2; BMP-9; GDF2; BMP9
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Cat. No.: HY-174781
Target:  

mRNA

Research Areas:  

Cancer

Human ACVRL1 mRNA encodes the human activin A receptor like type 1 (ACVRL1) protein. ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development.
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Cat. No.: HY-P704368
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GDF-2; BMP-9; GDF2; BMP9
Species:  
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Cat. No.: HY-P703981
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GDF-2; GDF2; BMP-9; BMP9
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Cat. No.: HY-RS05353
Research Areas:  

Others

GDF2 Human Pre-designed siRNA Set A contains three designed siRNAs for GDF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-186189
CAS No.: 3059216-68-8
Research Areas:  

Infection Cancer

OPA-S-S-alkyne is a cell surface protein-selective labeling agent. OPA-S-S-alkyne selectively labels hyper-reactive extracellular lysines including ROR2 K382 and ENG K285, blocks ENG-BMP9 interaction, and labels purified human serum albumin with minimal bias. OPA-S-S-alkyne can be used for the research of hematologic and influenza A virus infection .
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Cat. No.: HY-P992008

Target:  

TGF-β Receptor

Research Areas:  

Cardiovascular Disease

PF-07868489 is a recombinant monoclonal antibody targeting GDF2/BMP-9. PF-07868489 can be used for the research of pulmonary arterial hypertension (PAH). Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-RS19136
Research Areas:  

Others

Gdf2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gdf2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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