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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Burkitt's lymphoma
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Burkitt's lymphoma" in MCE Product Catalog:
Cat. No.: HY-P99273
CAS No.: 1165740-62-4
Target:
Research Areas:
WDR5-IN-1 is a potent and selective WD repeat domain 5 (WDR5) inhibitor, with a Kd of <0.02 nM. WDR5-IN-1 inhibits MLL1 histone methyltransferase (HMT) activity with an IC50 of 2.2 nM. WDR5-IN-1 diminishes MYC recruitment at WDR5-displaced genes and exhibits potent anti-proliferative effects in CHP-134 (neuroblastoma) and Ramos (Burkitt’s lymphoma) lines .
Cat. No.: HY-50055
CAS No.: 245329-78-6
EtDO-P4 is a nanomolar inhibitor of glycosphingolipid (GSL) synthesis. EtDO-P4 suppresses activation of the EGFR-induced ERK pathway and various receptor tyrosine kinases (RTKs). EtDO-P4 can be used for various types of cancer, including Burkitt’s lymphoma .
Cat. No.: HY-10984A
CAS No.: 202271-89-4
Synonyms: (S)-CC-4047
Target:
Research Areas:
(S)-Pomalidomide ((S)-CC-4047) is an angiogenesis-inhibiting drug with growth-inhibitory activity against B-cell tumors. (S)-Pomalidomide can induce complete tumor regression in BurKitt lymphoma cells. (S)-Pomalidomide serves as an immunomodulator with potential applications in inhibiting hematological malignancies .
Cat. No.: HY-P991057
CAS No.: 2376730-61-7
Target:
Research Areas:
JS25 is a selective and covalent inhibitor of BTK that inactivates BTK with an IC50 value of 5.8 nM by chelating Tyr551. JS25 inhibits cancer cells proliferation, pronounces cell death, and promotes murine xenograft model of Burkitt’s lymphoma. JS25 effectively crosses the blood-brain barrier .
Cat. No.: HY-P992349
Cat. No.: HY-158813
CAS No.: 2364639-42-7
Target:
Research Areas:
S-Geranylgeranyl-L-glutathione is a P2RY8 inhibitor and intercellular signaling molecule that exists endogenously in human bone marrow interstitial fluid. S-Geranylgeranyl-L-glutathione promotes the internalization of P2RY8 and antagonizes chemokine-induced activation of pAkt. S-Geranylgeranyl-L-glutathione negatively regulates the migration of B cells and T cells to the bone marrow, inhibits chemokine-mediated migration of germinal center B cells and follicular helper T cells, participates in lymphocyte guidance regulation, and modulates the germinal center response process. S-Geranylgeranyl-L-glutathione can be used in research related to diffuse large B-cell lymphoma and Burkitt lymphoma .
Cat. No.: HY-P72074
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AICDA; CDA2; Activation Induced Cytidine Deaminase; ARP2; AID; HEL-S-284; Single-Stranded DNA Cytosine Deaminase; Integrated Into Burkitt'S lymphoma Cell Line Ramos; Activation-Induced Cytidine Deaminase; Epididymis Secretory Protein Li 284; Cytidine Amin
Species:
Mouse
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
