15 Results for "

C8166

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "C8166" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0842
CAS No.: 174022-42-5
Synonyms: PA-457; MPC-4326; YK FH312
Bevirimat (PA-457, MPC-4326, YK FH312) is an inhibitor of HIV-1 viral particle maturation.Bevirimat specifically inhibits the final rate-limiting step in Gag processing, preventing the release of the mature capsid protein (CA) from its precursor (CA-SP1), resulting in the production of immature non-infectious viral particles. Bevirimat can be used in HIV-1 infection studies .
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Cat. No.: HY-18666
CAS No.: 497836-10-9
Target:  

HIV

Research Areas:  

Infection

D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).
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Cat. No.: HY-N3094
CAS No.: 1025023-04-4
Periglaucine A, a hasubanane-type alkaloid, can be isolated from Pericampylus glaucus. Periglaucine A can inhibits HBV surface antigen (HBsAg) secretion in Hep G2.2.15 cells. Periglaucine A also shows anti-HIV-1 activity in C8166 cells (EC50: 204 μM) .
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Cat. No.: HY-N6048
CAS No.: 850878-47-6
Lancifodilactone F (compound 1) can be isolated from the leaves and stems of Schisandra lancifolia. Lancifodilactone F has anti-HIV activity with EC50=20.69 μg/mL. Lancifodilactone F has cytotoxicity against C8166 cells (CC50 >200 μg/mL) .
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Cat. No.: HY-N0842R
CAS No.: 174022-42-5
Synonyms: PA-457 (Standard); MPC-4326 (Standard); YK FH312 (Standard)
Bevirimat (Standard) is the analytical standard of Bevirimat. This product is intended for research and analytical applications. Bevirimat (PA-457, MPC-4326, YK FH312) is an inhibitor of HIV-1 viral particle maturation.Bevirimat specifically inhibits the final rate-limiting step in Gag processing, preventing the release of the mature capsid protein (CA) from its precursor (CA-SP1), resulting in the production of immature non-infectious viral particles. Bevirimat can be used in HIV-1 infection studies[1][2][3][4].
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Cat. No.: HY-150599
CAS No.: 2493426-43-8
Target:  

HIV DNA/RNA Synthesis

Research Areas:  

Infection

HIV-1 inhibitor-43 is a potent HIV-1 inhibitor with an EC50 of 21.3 nM, 6.2 nM, < 0.7 nM and < 0.7 nM for Y188L, K103N-Y181C, K103N and Y181C, respectively. HIV-1 inhibitor-43 can reduce HIV-1 RNA and protein p24 expression .
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Cat. No.: HY-120075
CAS No.: 1522415-97-9
Purity:  99.83%
Target:  

Apoptosis

Research Areas:  

Cancer

TJ191 is a potent and specific anti-cancer agent that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells. TJ191 has no affects on the proliferation of other cancer cells or normal fibroblasts or immune cells. TJ191 can be used for cancer research .
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Cat. No.: HY-147903
CAS No.: 2459929-46-3
Target:  

DNA/RNA Synthesis HIV

Research Areas:  

Infection

HIV-1 inhibitor-42 (compound 5b) is a potent HIV-1 inhibitor, with an IC50 of 0.06 μM. HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase and DNA-dependent DNA polymerase, with IC50 values of 0.518 and 0.072 μM .
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Cat. No.: HY-147904
CAS No.: 2459929-62-3
Target:  

HIV

Research Areas:  

Infection

HIV-IN-5 (compound 5r) is a potent HIV-1 inhibitor, with an IC50 of 0.16 μM. HIV-IN-5 shows inhibition of HIV DNA-dependent DNA polymerization activity, with an IC50 of 2.18 μM. HIV-IN-5 can bind to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding pocket) .
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Cat. No.: HY-N19826
CAS No.: 883153-36-4
Lancifodilactone N is a nortriterpenoid found in the leaves and stems of Schisandra lancifolia. Lancifodilactone N shows anti-HIV-1 activity and can be used for the research of HIV-1 infection .
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Cat. No.: HY-N17741
CAS No.: 350229-67-3
Melanochromone is an HIV-1 reverse transcriptase inhibitor that exhibits anti-HIV-1 activity. Melanochromone can be used in research related to HIV-1 infection .
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Cat. No.: HY-N19901
CAS No.: 1210051-95-8
Schirubridilactone D is a HIV-1 inhibitor with an EC50 of 80.8 µg/mL. Schirubridilactone D is a nortriterpenoid isolated from the leaves and stems of Schisandra rubriflora. Schirubridilactone D inhibits HIV-1 replication and blocks HIV-1-induced cytopathic effects. Schirubridilactone D is applicable to research related to HIV-1 infection .
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Cat. No.: HY-N17392
CAS No.: 2771017-28-6
Artoheteronin is a prenylated coumarin found in the fruits of Artocarpus heterophyllus. Artoheteronin can inhibit HIV-1 reverse transcriptase activity with an EC50 of 0.18 μM. Artoheteronin shows anti-inflammatory activity and inhibits nitric oxide production. Artoheteronin can be used for the researches of HIV infection and inflammatory disease .
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Cat. No.: HY-126120
CAS No.: 154612-31-4
Target:  

HIV HIV Protease

Research Areas:  

Infection

BILA 1906 BS is a HIV protease inhibitor. BILA 1906 BS prevents HIV-1 replication via inhibition of viral protease-mediated cleavage of Gag and Gag-Pol polyprotein precursors during virion maturation. BILA 1906 BS blocks maturation of p24 proteins in wild-type HIV-1, impairing polyprotein processing and viral maturation. BILA 1906 BS can be used for the research of human immunodeficiency virus type 1 (HIV-1) infection .
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Cat. No.: HY-183926
CAS No.: 384361-09-5
Target:  

HIV Integrase

Research Areas:  

Infection

D719 is an HIV-1 integrase inhibitor. D719 binds to the hydrophobic pocket of HIV-1 integrase CCD dimer, disrupts interaction with LEDGF/P75, and prevents integrase nuclear translocation. D719 reduces HIV-1 p24 antigen production in acute infection of human T cells. D719 can be used for the research of HIV infection .
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