Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
CDH6
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "CDH6" in MCE Product Catalog:
Cat. No.: HY-164734
CAS No.: 2610074-57-0
Synonyms: R-DXd; DS-6000
Target:
Research Areas:
Raludotatug Deruxtecan is an antibody-drug conjugate targeting CDH6, with an EC50 of 64.7 ng/mL in humans, 70.4 ng/mL in cynomolgus monkeys, and 228 ng/mL in mice. Raludotatug Deruxtecan specifically binds to CDH6 on the surface of cancer cells, triggers lysosomal internalization, and releases the DXd payload that inhibits TOP1. Raludotatug Deruxtecan induces DNA damage, Chk1 phosphorylation, caspase-3 cleavage, apoptosis, and bystander cell death. Raludotatug Deruxtecan is applicable to research related to serous ovarian cancer and renal cell carcinoma .
Cat. No.: HY-P990028
CAS No.: 2610074-56-9
Research Areas:
Cat. No.: HY-P991108
Synonyms: HKT288 Antibody; LTV977
Target:
Research Areas:
Cat. No.: HY-RS02339
Target:
Research Areas:
CDH6 Human Pre-designed siRNA Set A contains three designed siRNAs for CDH6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17584
Target:
Research Areas:
Cdh6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdh6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24044
Target:
Research Areas:
Cdh6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdh6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P77429
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cadherin-6; Kidney cadherin; K-cadherin; CDH6
Species:
Source:
Cat. No.: HY-P704147
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Cadherin-6; Kidney Cadherin; CDH6
Cat. No.: HY-P701330
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cadherin-6; Cadherin6; K-cadherin; CDH6; CAD6; KCAD;
Cat. No.: HY-P83765
Synonyms: CAD6 antibody;
CADH6_HUMAN antibody;
Cadherin 6 antibody;
Cadherin 6 type 2 antibody;
Cadherin 6 type 2 K cadherin (fetal kidney) antibody;
Cadherin fetal kidney antibody;
Cadherin-6 antibody;
Cadherin6 antibody;
CDH 6 antibody;
CDH6 antibody;
K-cadherin antibody;
KCAD antibody;
Kidney cadherin antibody
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
