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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
CDK16
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "CDK16" in MCE Product Catalog:
41
41 Cited Publications
NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 μM, 0.706 μM, and 0.605 μM, respectively. NVP-2 induces cell apoptosis.
Cat. No.: HY-163170
CAS No.: 2741262-15-5
FMF-04-159-R is a cyclin-dependent kinase CDK14 and CDK16 inhibitor with IC50 values of 5.9 and 139.1 nM .
Target:
PROTACs CDK AAK1 Cyclin G-associated Kinase (GAK) Salt-inducible Kinase (SIK) LIM Kinase (LIMK) Wee1 SnRK
Research Areas:
RSS0680 is a small noncoding RNA (sRNA) targeting the mRNA ribosome binding site (RBS) and a PROTAC. RSS0680 competitively binds to RBS through the conserved CCUCCUCCC anti-Shine-Dalgarno (aSD) sequence and inhibits the translation initiation of target genes. RSS0680 can interact with the DUF1127 protein CcaF1, regulate its own stability and participate in bacterial oxidative stress defense, enhancing the host's resistance to heat shock and oxidative damage by affecting pathways such as C1 metabolism and pyruvate dehydrogenase complex. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used to study diseases or disorders mediated by aberrant kinase activity and regulatory mechanisms of noncoding RNAs in α-proteobacteria[1][2].
Cat. No.: HY-RS02366
Target:
Research Areas:
CDK16 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK16 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02367
Target:
Research Areas:
Cdk16 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdk16 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02368
Target:
Research Areas:
Cdk16 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdk16 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P80612A
Synonyms: PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE
Cat. No.: HY-P702696
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CDK16; PCTAIRE-Motif Protein Kinase 1; Prev. PCTK1; FLJ16665; PCTAIRE1; Testis Secretory Sperm-Binding Protein Li 224n; PCTGAIRE; Serine/Threonine-Protein Kinase; PCTAIRE; PCTAIRE Protein Kinase 1; Serine/Threonine-Protein Kinase PCTAIRE-1; Cyclin-Depende
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P76536
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CDK16; PCTAIRE-Motif Protein Kinase 1; Prev. PCTK1; FLJ16665; PCTAIRE1; Testis Secretory Sperm-Binding Protein Li 224n; PCTGAIRE; Serine/Threonine-Protein Kinase; PCTAIRE; PCTAIRE Protein Kinase 1; Serine/Threonine-Protein Kinase PCTAIRE-1; Cyclin-Depende
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
