9 Results for "

CLDN1

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "CLDN1" in MCE Product Catalog:

Cat. No.: HY-P991200

Target:  

HCV Claudin

Research Areas:  

Infection

OM-7D3-B3 is an antibody-based antiviral agent targeting the tight junction protein CLDN1 (Kd=4 nM). By binding to the first extracellular domain of CLDN1, OM-7D3-B3 disrupts the formation of the CLDN1-CD81 co-receptor complex, thereby effectively inhibiting the entry of hepatitis C virus (HCV). OM-7D3-B3 not only prevents de novo and chronic HCV infections in humanized liver chimeric mice and uPA-SCID mice transplanted with human livers, but also exhibits favorable safety with no toxic effects observed. OM-7D3-B3 serves as a critical tool for research on HCV infection mechanisms and antiviral drug development [1] .
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Cat. No.: HY-P990045
CAS No.: 2749515-10-2
Synonyms: ALE.F02

Target:  

Claudin

Research Areas:  

Endocrinology

Lixudebart (ALE.F02) is a humanized immunoglobulin G1-kappa, anti-CLDN1 monoclonal antibody. Lixudebart disrupts CLDN1 interactions with CD44 and MMP14, reduces renal macrophage infiltration, epithelial activation, and urinary albumin-to-creatinine ratio, and attenuates glomerulosclerosis. Lixudebart can be used for the research of focal segmental glomerulosclerosis [1].
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Cat. No.: HY-RS02762
Research Areas:  

Others

CLDN1 Human Pre-designed siRNA Set A contains three designed siRNAs for CLDN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990984
CAS No.: 2922054-25-7

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

HY-P990984 is an CLDN1-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) [1].
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Cat. No.: HY-RS18807
Research Areas:  

Others

Cldn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cldn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25296
Research Areas:  

Others

Cldn1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cldn1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P86518
Synonyms: CLDN1; CLD1; SEMP1; Claudin-1; Senescence-associated epithelial membrane protein

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P992219

Target:  

Claudin

Research Areas:  

Inflammation/Immunology

Anti-Claudin 1 Antibody is a monoclonal antibody targeting CLDN1/CLD1/SEMP1. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-Claudin 1 Antibody, please refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P702245
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Claudin-1; Senescence-associated epithelial membrane protein
Species:  
Source:  
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