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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
CMKLR1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "CMKLR1" in MCE Product Catalog:
13
13 Publications Verification
Research Areas:
α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC50 of 9 μM. α-NETA is a potent ALDH1A1 (IC50=0.04 µM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibits cholinesterase (ChE; IC50=84 µM) and acetylcholinesterase (AChE; IC50=300 µM). α-NETA has anti-cancer activity [1] .
4
4 Cited Publications
Cat. No.: HY-P1844A
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4
4 Cited Publications
Cat. No.: HY-P1844
CAS No.: 676367-27-4
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CMKLR1 antagonist 1 (compound S-26d) is a potent and orally active chemokine-like receptor 1 (CMKLR1) antagonist, with a pIC50 value of 7.44 in hCMKLR1-transfected CHO cells. CMKLR1 antagonist 1 can be used for psoriasis and metabolic diseases research [1].
Cat. No.: HY-174140
CAS No.: 932973-77-8
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VU0514009 is a competitive chemokine-like receptor 1 (CMKLR1) antagonist (EC50=2 nM). VU0514009 prevents chemerin-9-induced arrestin recruitment and receptor internalization, significantly reducing Ca 2+ flux response in HEK293 cells. VU0514009 is promising for research of inflammatory diseases and metabolic syndrome [1].
Cat. No.: HY-RS02860
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CMKLR1 Human Pre-designed siRNA Set A contains three designed siRNAs for CMKLR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174139
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CMKLR1 antagonist 2 (compound 16) is a full and competitive chemerin/chemokine-like receptor 1 (CMKLR1) antagonist with an IC50 of 37 μM. CMKLR1 antagonist 2 can be used for study of inflammation [1].
Cat. No.: HY-RS16979
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Cmklr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cmklr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23422
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Cmklr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cmklr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702250
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Chemerin-like receptor 1; Chemokine-like receptor 1; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
