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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
CMP-Neu5Ac
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "CMP-Neu5Ac" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: CMP-Neu5Ac sodium salt
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Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
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Cat. No.: HY-E70065
CAS No.: 71124-51-1
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alpha-2,3-Sialyltransferase (PmST2) is a monofunctional α2-3 sialyltransferase that belongs to the GT52 family of Carbohydrate-Active enZymes (CAZy). alpha-2,3-Sialyltransferase (PmST2) catalyzes the transfer of sialic acid from CMP-Neu5Ac to the C3 position of galactose in lactosyl lipids, β1-4 linked galactosyl disaccharide lipids, and β-galactosyl monosaccharide lipids, with its catalytic activity decreasing sequentially toward these substrate classes. The function ofalpha-2,3-Sialyltransferase (PmST2) is independent of divalent metal cations and disulfide bonds, and it retains α2-3 sialyltransferase activity over a pH range of 4.5-10.0, with optimal activity observed at pH 6.0 .
Cat. No.: HY-112942B
CAS No.: 149007-28-3
Synonyms: CMP-Neu5Ac disodium
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CMP-Sialic acid (CMP-Neu5Ac) sodium is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .
Cat. No.: HY-E70019
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alpha-2-3,6-sialidase (BiNanH2) is a sialyltransferase, is often used in biochemical studies. alpha-2-3,6-sialidase (BiNanH2) catalyzes α-2,3/2,6-sialyltransfer from CMP-Neu5Ac to galactoside acceptors .
Cat. No.: HY-188400
CAS No.: 3138013-03-0
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P-SiaFNEtoc is a Sialyltransferase inhibitor that blocks sialic acid capping of glycans. P-SiaFNEtoc forms CMP-SiaFNEtoc, reduces endogenous CMP-Neu5Ac, feedback-inhibits GNE, and depletes sialylation on N-glycans and O-GalNAc glycans. P-SiaFNEtoc decreases cell surface sialoglycan levels, VEGF and DKK-1 secretion, Tn antigen levels, and cell cycle checkpoint/E2F target gene expression, while inducing p27/Kip1 and fucosylation. P-SiaFNEtoc can be used in research on prostate cancer, and melanoma [5].
Cat. No.: HY-RS22126
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Cmas Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cmas gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
