7 Results for "

Complex3

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Complex3" in MCE Product Catalog:

Cat. No.: HY-158726
CAS No.: 2480150-28-3
Complex 3 is a fluorescent dithiocarbazate-copper complex with anticancer activity, which localizes to mitochondria. Complex 3 displays excitation/emission maxima of 455-495/535 nm, respectively. Complex 3 inhibits the growth of BxPC-3, AsPC-1, PANC-1, and WI38 pancreatic cancer cells with IC50 values of 0.74, 0.41, 0.62, and 2.06 µM, respectively. Complex 3 induces lipid peroxidation and mitochondrial rupture and shrinkage in AsPC-1 cells. Complex 3 also induces mitochondrial apoptosis and cytokine-cytokine receptor interaction dysfunction in AsPC-1 cells. Complex 3 reduces tumor volume in an AsPC-1 mouse xenograft model .
loading...
    loading...
Cat. No.: HY-W015329
CAS No.: 702-82-9
Research Areas:  

Others

3-Amino-1-adamantanol is a p38α‑TAB1 interaction inhibitor. 3-Amino-1-adamantanol occupies the non-canonical docking site of p38α, inhibits the phosphorylation of TAB1 by activated pp38α, and disrupts the formation of the p38α‑TAB1 protein complex. 3-Amino-1-adamanol is applicable to research related to myocardial ischemic injury; it also serves as an intermediate for the synthesis of compounds such as Vildagliptin (HY-14291) .
loading...
    loading...
Cat. No.: HY-169957
CAS No.: 3081736-89-9
Research Areas:  

Cancer

ROS-ERS inducer 2 (Complex 3f) triggers intracellular ROS generation and affect the function of mitochondria. promote the release of damage-associated molecular patterns (DAMPs), induce immunogenic cell death (ICD) and activates endoplasmic reticulum stress (ERS). ROS-ERS inducer 2 plays an important role in anti-liver cancer research .
loading...
    loading...
Cat. No.: HY-P82372
Synonyms: AP-3 adaptor Complex mu3A subunit; Adaptor-related protein Complex 3 subunit mu-1; Mu-adaptin 3A; Mu3A-adaptin

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P82372A
Synonyms: AP-3 adaptor Complex mu3A subunit; Adaptor-related protein Complex 3 subunit mu-1; Mu-adaptin 3A; Mu3A-adaptin

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-K6022

MCE ECM Gentle Dissociation Solution is a gentle ECM-degrading enzyme mixture derived from marine bacteria and Bacillus species, specifically formulated for efficient and low-damage digestion of in-vitro cell systems. It selectively degrades extracellular matrix components while minimizing disruption to the cell membrane and intercellular junctions, thereby significantly reducing mechanical stress during dissociation. This product is compatible with a wide range of cell types, including stem cell colonies, primary cells, neural cells, and organoids, and is particularly well suited for gentle yet effective dissociation of brain organoids and other complex 3D structures.

loading...
    loading...
Cat. No.: HY-N21727
CAS No.: 1094030-07-5
3-Hydroxyhericenone F is a neuroprotective agent. Hydroxyhericenone F protects cells against NaN3-induced toxicity, ultrastructural changes, and alterations in mitochondrial respiratory chain complexes. 3-Hydroxyhericenone F decreases intracellular ROS and calcium levels, increases mitochondrial membrane potential and ATP levels, attenuates NaN3 -induced changes in apoptosis-related proteins, and protects neuronal cells from endoplasmic reticulum stress-dependent cell death. 3-Hydroxyhericenone F can be used in research related to cancer, Alzheimer's disease, and neurodegenerative diseases [3].
loading...
    loading...