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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
172 Results for "
DOPE
" in MedChemExpress (MCE) Product Catalog:
Products (172)
172 Results for "DOPE" in MCE Product Catalog:
14
14 Cited Publications
Synonyms: Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
Target:
Liposome Endogenous Metabolite ACSL Family Amino acid Transporter Ferroptosis Glutathione Peroxidase
Forschungsgebiete:
DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .
1
1 Cited Publications
Art. -Nr.: HY-W440827
DOPE-PEG2000-COOH is a PEG polymer containing unsaturated DOPE phospholipids and carboxylic acids. DOPE-PEG2000-COOH can be used to prepare liposomes or other nanoparticles for drug delivery .
Forschungsgebiete:
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
Art. -Nr.: HY-N16025
CAS. Nr.: 2342575-85-1
Synonyms: DOPE-PEG2000-NH2 ammonium
Target:
Forschungsgebiete:
DOPE-PEG2000-Amine (DOPE-PEG2000-NH2) ammonium is a polyethylene glycol-derivatized phospholipid that can be used to construct liposomes and lipid nanoparticles. DOPE-PEG-Amine ammonium is used for non-covalent functionalization of single-walled carbon nanotubes (SWCNTs) to enhance their water dispersibility and biocompatibility. DOPE-PEG-Amine ammonium can be applied in research related to photothermal applications .
Art. -Nr.: HY-W440988
DOPE-mPEG2000 is a phospholipid polydisperse PEG (or DOPE liposome), can be used for preparation of targeted delivery of liposomal drug and giant unilamellar vesicles (GUVs). DOPE-mPEG2000 significantly reduces the pH-sensitivity of the liposome in a concentration dependent manner .
Art. -Nr.: HY-W800805
CAS. Nr.: 2295813-15-7
DOPE-Mal is an N-maleimide-derived phosphatidylethanolamine. DOPE-Mal does not interfere with fatty acyl chains or alter lipid bilayer permeability; it increases lipid bilayer order, reduces fluidity, induces conformational changes in phospholipid polar heads and enhances their hydration. DOPE-Mal can be used as a component to prepare maleimide-displaying liposomes, enabling peptide conjugation via maleimide-thiol coupling. DOPE-Mal can be used to prepare Liposomes for delivering Doxorubicin (HY-15142A) to hepatocytes. DOPE-Mal is applicable to research related to hepatocellular carcinoma and lung cancer .
Art. -Nr.: HY-164035
Target:
Forschungsgebiete:
DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
Art. -Nr.: HY-W440987
DOPE-mPEG1000 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. DOPE-mPEG1000 can be used in drug delivery research .
Art. -Nr.: HY-160272
Target:
Forschungsgebiete:
DOPE-PEG2000-Fluor 488 is a PEG lipid, composed of a DOPE phospholipid and a Fluor 488 fluorophore. DOPE is an unsaturated phospholipid. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm .
Art. -Nr.: HY-160280
Target:
Forschungsgebiete:
DOPE-PEG2000-Fluor 647 is a PEG-lipid-dye conjugate. composed of a DOPE phospholipid and a Fluor 647 dye .
Art. -Nr.: HY-N15995
CAS. Nr.: 2342575-87-3
Target:
Forschungsgebiete:
DOPE-PEG(2000) Carboxylic acid sodium is a stabilizer. DOPE-PEG(2000) Carboxylic acid sodium produce a coating around the ferrofluid droplet chains which are dispersed in 5CB. DOPE-PEG(2000) Carboxylic acid sodium tends to fold, effectively shielding the surrounding LC molecules from the homeotropic anchoring at the droplet interface and leading to smaller deformations and thus also creating a more stable interface .
Art. -Nr.: HY-160273
Target:
Forschungsgebiete:
DOPE-PEG5000-Fluor 488 is a PEG lipid, composed of a DOPE phospholipid and a Fluor 488 dye .
Art. -Nr.: HY-N15803
CAS. Nr.: 2316360-42-4
Category:
Target:
Art. -Nr.: HY-175410
CAS. Nr.: 3081750-70-8
Synonyms: 1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8
DOPE-C8 (1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8) is a zwitterionic phospholipid derived from DOPE that has been used to generate lipid nanoparticles (LNPs) for in vivo delivery of mRNA .
Art. -Nr.: HY-W440991
Synonyms: DOPE-PEG2000-NH2
Target:
Forschungsgebiete:
DOPE-PEG2000-Amine (DOPE-PEG2000-NH2) is a polyethylene glycol-derivatized phospholipid that can be used to construct liposomes and lipid nanoparticles. DOPE-PEG-Amine is used for non-covalent functionalization of single-walled carbon nanotubes (SWCNTs) to enhance their water dispersibility and biocompatibility. DOPE-PEG-Amine can be applied in research related to photothermal applications .
Art. -Nr.: HY-166323
CAS. Nr.: 1246297-94-8
Target:
Forschungsgebiete:
DOPE-N-nonadecanoyl is an ester product.
Art. -Nr.: HY-160276
DOPE-PEG5000-Fluor 555 is consist of a DOPE phospholipid which is an unsaturated phospholipid and a Fluor 555 dye which is a bright orange cyanine dye that can be used in fluorescence microscopy, FRET and other in vivo imaging techniques.
Art. -Nr.: HY-N16036
CAS. Nr.: 2342575-90-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
