3 Results for "

Deguelin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Deguelin" in MCE Product Catalog:

15
Deguelin
Deguelin
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15 Cited Publications
Cat. No.: HY-13425
CAS No.: 522-17-8
Purity:  99.20%
Synonyms: (-)-Deguelin; (-)-cis-Deguelin
Category:  

Flavonoids Isoflavanones Derris trifoliata Lour. Leguminosae Extract Plants Disease Research Fields Biological Pesticide Research Cancer Agricultural Research

Target:  

Akt Autophagy Apoptosis

Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
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Deguelin (Standard)
Deguelin (Standard)
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Cat. No.: HY-13425R
CAS No.: 522-17-8
Synonyms: (-)-Deguelin (Standard); (-)-cis-Deguelin (Standard)
Category:  

Flavonoids Isoflavanones Derris trifoliata Lour. Leguminosae Extract Plants

Target:  

Akt Autophagy Apoptosis Reference Standards

Deguelin (Standard) is the analytical standard of Deguelin. This product is intended for research and analytical applications. Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
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Anticancer agent 170
Anticancer agent 170
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Cat. No.: HY-W548095
CAS No.: 24126-98-5
Target:  

Drug Derivative

Research Areas:  

Cancer

Anticancer agent 170 (compound 3a) is a keton derivative of Deguelin (HY-13425), and shows potency anti-cancer activity against A549, with the IC50 of 6.62 μM .
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