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Cat. No.: HY-W548095

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Anticancer agent 170

Anticancer agent 170 (compound 3a) is a keton derivative of Deguelin (HY-13425), and shows potency anti-cancer activity against A549, with the IC₅₀ of 6.62 μM.

For research use only. We do not sell to patients.

CAS No.: 24126-98-5
Formula: C₁₆H₁₆O₅
Molecular Weight:288.30

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Anticancer agent 170 Chemical Structure

CAS No.: 24126-98-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Anticancer agent 170 (compound 3a) is a keton derivative of Deguelin (HY-13425), and shows potency anti-cancer activity against A549, with the IC₅₀ of 6.62 μM^[1].

IC₅₀ & Target

6.62 μM(A549)^[1]

Chemical Information

CAS No. 24126-98-5
Appearance Solid
Molecular Weight 288.30
Formula C₁₆H₁₆O₅
Color White to off-white
SMILES

COC1=CC=C(CC(C2=CC=C(O)C=C2O)=O)C=C1OC
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. John Alfon P. Francisco, et al. Inhibitory Effects of B-, C-, and E-Ring-Truncated Deguelin Derivatives Against A549, HCT116, and MCF-7 Cancer Cells. ACS Omega 2023, 8, 45, 43109–43117

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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