84 Results for "

Difluoro

" in MedChemExpress (MCE) Product Catalog:
Products (84)

84 Results for "Difluoro" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-120166
CAS No.: 214491-43-7
Purity:  99.05%
Synonyms: 6,8-Difluoro-4-methylumbelliferyl phosphate
Target:  

Phosphatase

Research Areas:  

Others

DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader .
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1
1 Cited Publications
Cat. No.: HY-111469
CAS No.: 888213-72-7
Purity:  99.14%
Target:  

Phosphatase

Research Areas:  

Metabolic Disease

CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance .
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Cat. No.: HY-138253
CAS No.: 114248-23-6
Purity:  99.87%
Synonyms: dFdU; 2',2'-Difluoro-2'-deoxyuridine
Research Areas:  

Cancer

2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells .
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Cat. No.: HY-153345
CAS No.: 2345733-40-4
Purity:  99.67%
Glucocorticoid receptor agonist-1 phosphate(2,6-difluoro) Ala-Ala-Br is an Drug-linker conjugates for ADC that can be used as a reaction reagent for the synthesis of anti-CD40 antibody agent conjugates (ADCs) .
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Cat. No.: HY-W012725
CAS No.: 367-27-1
2,4-Difluorophenol is a difluoro-substituted phenol that serves as a starting material for the synthesis of 4,6-difluoro-5,7-dihydroxytryptamine .
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Cat. No.: HY-167830
CAS No.: 2242777-37-1
SDM-8 is a difluoro-analog of UCB-J (HY-136873).SDM-8 shows high SV2A binding affinity with a Ki of 0.58 nM. SDM-8 can be used in the study of Alzheimer's disease .
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Cat. No.: HY-138253R
CAS No.: 114248-23-6
Synonyms: dFdU (Standard); 2',2'-Difluoro-2'-deoxyuridine (Standard)
Research Areas:  

Cancer

2′,2′-Difluorodeoxyuridine (Standard) is the analytical standard of 2′,2′-Difluorodeoxyuridine. This product is intended for research and analytical applications. 2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells.
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Cat. No.: HY-138253S
CAS No.: 1233921-75-9
Synonyms: dFdU-13C,15N2; 2',2'-Difluoro-2'-deoxyuridine-13C,15N2
2′,2′-Difluorodeoxyuridine- 13C, 15N2 (dFdU- 13C, 15N2) is a 13C- and 15N-labeled compound. 2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells .
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Cat. No.: HY-W050049
CAS No.: 122111-01-7
2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate is a chemically synthesized fluorinated carbohydrate derivative that can be used in glycobiology research .
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Cat. No.: HY-136595
CAS No.: 73246-30-7
Purity:  98.39%
Target:  

Phosphatase

Research Areas:  

Others

3,5-Difluoro-L-tyrosine is a functional, tyrosinase-resistant mimetic of tyrosine. 3,5-Difluoro-L-tyrosine can be used to analyze the substrate specificity of protein tyrosine phosphatases (PTPs) .
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Cat. No.: HY-P5372A
Research Areas:  

Cancer

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
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Cat. No.: HY-W109864
CAS No.: 655-14-1
Synonyms: 1,4-Benzenedicarboxylicacid,2,5-Difluoro
Target:  

MOFs

Research Areas:  

Others

2,5-Difluoroterephthalic acid (1,4-Benzenedicarboxylicacid,2,5-difluoro) is a metal-organic framework (MOF).
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Cat. No.: HY-135151
CAS No.: 693794-20-6
Synonyms: Fluoroatorvastatin
Target:  

Drug Metabolite

Research Areas:  

Cardiovascular Disease

Difluoro atorvastatin (Fluoroatorvastatin) is an impurity of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively .
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Cat. No.: HY-D1640
CAS No.: 152290-47-6
Research Areas:  

Others

5,5'-Difluoro BAPTA tetrapotassium is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA tetrapotassium shows large 19F NMR chemical shifts upon chelating divalent cations. 5,5'-Difluoro BAPTA tetrapotassium has high selectivity for Ca 2+. 5,5'-Difluoro BAPTA tetrapotassium can inhibit the growth of pollen tube .
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Cat. No.: HY-W039283
CAS No.: 345-24-4
Target:  

MCHR1 (GPR24)

Research Areas:  

Neurological Disease Cancer

MCH-1 antagonist 2 (l-BROMO-2,4-DIFLUORO-5-NITROBEN-ZENE) is a melanin concentrating hormone-1 (MCH1) receptor-selective 4-aryl piperidine. MCH-1 antagonist 2 can be used for the research of depression, anxiety, obesity, urge incontinence, urinary incontinence, major depression, bipolar disorder, agoraphobia, specific phobia, social phobia, obsessive-compulsive disorder, post-traumatic stress disorder, acute stress disorder, urinary frequency, urinary urgency, nocturia, enuresis, bulimia, bulimia nervosa, anorexia nervosa, major depressive disorder, dysthymic disorder, bipolar 1 and 2 disorders, schizoaffective disorder, cognitive disorders with depressed mood, personality disorders, insomnia, hypersomnia, narcolepsy, circadian rhythm sleep disorder, nightmare disorder, sleep terror disorder, sleepwalking disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, overactive bladder .
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Cat. No.: HY-W107372
CAS No.: 1189458-67-0
Target:  

MOFs

Research Areas:  

Others

4,4'-Difluoro-2,2'-bipyridine is a metal-organic framework (MOF).
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Cat. No.: HY-22038
CAS No.: 50889-46-8
Target:  

Drug Intermediate

Research Areas:  

Others

Dimethyl (3,3-difluoro-2-oxoheptyl)phosphonate is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-W041076
CAS No.: 32133-37-2
Research Areas:  

Others

3,5-Difluoro-DL-phenylalanine is a phenylalanine derivative that can be used for amino acids synthesis .
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Cat. No.: HY-W001728
CAS No.: 1864060-27-4
Target:  

PROTAC Linkers

Research Areas:  

Cancer

tert-Butyl 3,3-difluoro-4-((methylsulfonyloxy)methyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
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Cat. No.: HY-W244439
CAS No.: 1258639-00-7
Target:  

PROTAC Linkers

Research Areas:  

Cancer

tert-Butyl 4-(2-ethoxy-1,1-difluoro-2-oxoethyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
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